Abstract: A device for electronic sequencing of polymers consisting of a tunnel gap that is self-aligned with a nanochannel.

Abstract: A device for electronic sequencing of polymers consisting of a tunnel gap that is self-aligned with a nanochannel.

Abstract: A method to identify a chemical target trapped in a tunnel junction with a high probability of a correct assignment based on, a single read of the tunnel current signal. The method recognizes and rejects background signals produced in the absence of target molecules, and do so accurately without rejecting useful signals from the target molecules. The identity of signals generated by electron tunneling through an analyte is provided and comprises determining a plurality of characteristics of each signal current spike, generating one or more training signals with a set of analytes, where the analytes may comprise a first analyte, and using the training signals to find one or more boundaries in a space of dimension equal to one or more parameters, wherein the space is partitioned such that a signal from the first analyte of interest is separated from a signal from the second analyte of interest.