Patents by Inventor Brian Chow

Brian Chow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240085332
    Abstract: Provided herein is a stimulation and measurement device. The stimulation and measurement device includes a microwell plate having a top side, a bottom side, and at least one well extending from the top side towards the bottom side; a first assembly removably positioned on the top side of the microwell plate; a second assembly removably positioned on the bottom side of the microwell plate; and a microcontroller. The first assembly includes a first printed circuit board having at least one pair of stimulating light emitting diodes (LEDs) positioned thereon to align with one of the wells. The second assembly includes a second printed circuit board having at least one photodiode positioned thereon to align with one of the pairs of stimulating LEDs, and at least one excitation LED paired with each of the photodiodes. The microcontroller is configured to control the stimulating LED(s), the photodiode(s), and the excitation LED(s).
    Type: Application
    Filed: September 14, 2023
    Publication date: March 14, 2024
    Inventors: William Benman, Lukasz Bugaj, Brian Chow, Saachi Datta, David Gonzalez-Martinez, Jose Avalos
  • Patent number: 11814412
    Abstract: De novo artificial protein based reporters that may be expressed in eukaryotic (e.g., mammalian) cells and methods of using the same are provided herein.
    Type: Grant
    Filed: June 29, 2021
    Date of Patent: November 14, 2023
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Goutham Kodali, Molly Marie Sheehan, Joshua Mancini, Bohdana Marie Discher, Michael Magaraci, Nathan M. Ennist, Brian Chow, Peter Leslie Dutton, Christopher Moser
  • Publication number: 20220383683
    Abstract: A computer-implemented method, a computer system and a computer program product secure access to a restricted area. The method includes capturing, by a camera, a first image of a face of a first person and a second image of a face of a second person. The method also includes determining whether the face of the first person is included in a database of persons authorized to access the restricted area. The method further includes determining whether the second person is in proximity to the first person. In addition, the method includes determining whether the second person is authorized to access the restricted area. Finally, the method includes transmitting a signal that the second person is authorized to access the restricted area in response to determining that the second person is in proximity to the first person and the second person is authorized to access the restricted area.
    Type: Application
    Filed: May 26, 2021
    Publication date: December 1, 2022
    Inventors: Cristi Nesbitt Ullmann, Brian Chow, Carole Rhoads Corley
  • Patent number: 11514740
    Abstract: A computer-implemented method, a computer system and a computer program product secure access to a restricted area. The method includes capturing, by a camera, a first image of a face of a first person and a second image of a face of a second person. The method also includes determining whether the face of the first person is included in a database of persons authorized to access the restricted area. The method further includes determining whether the second person is in proximity to the first person. In addition, the method includes determining whether the second person is authorized to access the restricted area. Finally, the method includes transmitting a signal that the second person is authorized to access the restricted area in response to determining that the second person is in proximity to the first person and the second person is authorized to access the restricted area.
    Type: Grant
    Filed: May 26, 2021
    Date of Patent: November 29, 2022
    Assignee: International Business Machines Corporation
    Inventors: Cristi Nesbitt Ullmann, Brian Chow, Carole Rhoads Corley
  • Publication number: 20210340183
    Abstract: De novo artificial protein based reporters that may be expressed in eukaryotic (e.g., mammalian) cells and methods of using the same are provided herein.
    Type: Application
    Filed: June 29, 2021
    Publication date: November 4, 2021
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Goutham KODALI, Molly Marie SHEEHAN, Joshua MANCINI, Bohdana Marie DISCHER, Michael MAGARACI, Nathan M. ENNIST, Brian CHOW, Peter Leslie DUTTON, Christopher MOSER
  • Patent number: 11084848
    Abstract: De novo artificial protein based reporters that may be expressed in eukaryotic (e.g., mammalian) cells and methods of using the same are provided herein.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: August 10, 2021
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Goutham Kodali, Molly Marie Sheehan, Joshua Mancini, Bohdana Marie Discher, Michael Magaraci, Nathan M. Ennist, Brian Chow, Peter Leslie Dutton, Christopher Moser
  • Publication number: 20200165301
    Abstract: De novo artificial protein based reporters that may be expressed in eukaryotic (e.g., mammalian) cells and methods of using the same are provided herein.
    Type: Application
    Filed: November 4, 2016
    Publication date: May 28, 2020
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Goutham KODALI, Molly Marie SHEEHAN, Joshua MANCINI, Bohdana Marie DISCHER, Michael MAGARACI, Nathan M. ENNIST, Brian CHOW, Peter Leslie DUTTON, Christopher MOSER
  • Publication number: 20120328061
    Abstract: Method, apparatus, and computer program product example embodiments use native clock timing of a first wireless communications protocol to establish synchronization of a wireless network of a second wireless communications protocol. According to an example embodiment of the invention, a method comprises maintaining a native clock time in a first wireless communications protocol; activating one or more wireless messages in a second wireless communications protocol, based on the native clock time of the first wireless communications protocol; receiving a wireless message in the first wireless communications protocol; and transmitting one or more second wireless messages in the first wireless communications protocol, including information related to the native clock time, to enable a receiving apparatus to synchronize its activation of one or more messages in the second wireless communications protocol, with the one or more wireless messages activated in the second wireless communications protocol.
    Type: Application
    Filed: June 27, 2011
    Publication date: December 27, 2012
    Applicant: Nokia Corporation
    Inventor: Brian CHOW
  • Publication number: 20070292943
    Abstract: A molecular shuttle device comprises two or more molecular subunits connected to form a molecular chain, with the subunits defining binding positions along the molecular chain, and a shuttle capable of binding at each of the binding positions, wherein the shuttle moves between binding positions in response to one or more input signals which interact with the molecular subunits. In some embodiments the one or more input signals comprise an input signal sequence that interacts with the molecular chain and the shuttle moves between binding positions in response to the input sequence.
    Type: Application
    Filed: April 9, 2007
    Publication date: December 20, 2007
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Joseph JACOBSON, David MOSLEY, Brian CHOW
  • Publication number: 20070207487
    Abstract: In a method for creating polymer arrays through photoelectrochemically modulated acid/base/radical generation for combinatorial synthesis, electrochemical synthesis is guided by a spatially modulated light source striking a semiconductor in an electrolyte solution. A substrate having at its surface at least one photoelectrode that is proximate to at least one molecule bearing at least one chemical functional group is provided, along with a reagent-generating chemistry co-localized with the chemical functional group and capable of generating reagents when subjected to a potential above a threshold. An input potential is then applied to the photoelectrode that exceeds the threshold in the presence of light and that does not exceed the threshold in the absence of light, causing the transfer of electrons to or from the substrate, and creating a patterned substrate. The process is repeated until a polymer array of desired size is created.
    Type: Application
    Filed: January 25, 2007
    Publication date: September 6, 2007
    Inventors: Christopher Emig, Brian Chow, Joseph Jacobson
  • Patent number: 7181178
    Abstract: A method of controlling the gain of a receiver of a radio device suitable for use in a spread spectrum communication system comprising at least two base stations and a radio device, the method comprising estimating the extent to which received signal strength will decrease at the radio device when a base station ceases transmission and calculating a gain control signal to increase the gain of the receiver on the basis of the estimation.
    Type: Grant
    Filed: June 27, 2002
    Date of Patent: February 20, 2007
    Assignee: Nokia Corporation
    Inventor: Brian Chow
  • Publication number: 20050255477
    Abstract: This invention generally relates to nucleic acid synthesis, in particular DNA synthesis. More particularly, the invention relates to the production of long nucleic acid molecules with precise user control over sequence content. This invention also relates to the prevention and/or removal of errors within nucleic acid molecules.
    Type: Application
    Filed: December 10, 2003
    Publication date: November 17, 2005
    Inventors: Peter Carr, Brian Chow, Joseph Jacobson, David Mosley, Christopher Emig
  • Publication number: 20050227235
    Abstract: This invention generally relates to nucleic acid synthesis, in particular DNA synthesis. More particularly, the invention relates to the production of long nucleic acid molecules with precise user control over sequence content. This invention also relates to the prevention and/or removal of errors within nucleic acid molecules.
    Type: Application
    Filed: December 10, 2003
    Publication date: October 13, 2005
    Inventors: Peter Carr, Brian Chow, Joseph Jacobson, David Mosley, Christopher Emig
  • Publication number: 20040264263
    Abstract: This invention generally relates to solution-based molecular shuttle devices. More particularly, this invention relates to solution-based molecular switches, molecular assemblies, and molecular memory devices and methods for producing the same. In some embodiments the devices are made from molecular chains constructed from molecular subunits which define binding positions and shuttles that are capable of moving along the chains.
    Type: Application
    Filed: July 17, 2003
    Publication date: December 30, 2004
    Applicant: ASSIGNEE-COMPANY-NAME
    Inventors: Joseph M. Jacobson, David W. Mosley, Brian Chow
  • Publication number: 20040185808
    Abstract: A method of controlling the gain of a receiver of a radio device suitable for use in a spread spectrum communication system comprising at least two base stations and a radio device, the method comprising estimating the extent to which received signal strength will decrease at the radio device when a base station ceases transmission and calculating a gain control signal to increase the gain of the receiver on the basis of the estimation.
    Type: Application
    Filed: April 26, 2004
    Publication date: September 23, 2004
    Inventor: Brian Chow
  • Patent number: 6256099
    Abstract: The present invention relates to methods and system for measuring three dimensional spatial coordinates and for external camera calibration necessary for that measurement. A simple pattern of light is projected onto a surface and used as a photogrammetric target. Images of the simple pattern are captured by two or more cameras, and processed by a computer provided with software using conventional algorithms to identify homologous points. Either, these points are used to calculate the external calibration of the cameras, or they are used in conjunction with previously calculated external camera calibration in order to calculate three dimensional spatial coordinates on the surface of an object to be measured.
    Type: Grant
    Filed: October 25, 1999
    Date of Patent: July 3, 2001
    Inventors: Frederick Kaufman, Jeffrey Brian Chow, Robert Newton James, Curtis Earle Lang