Abstract: Methods and devices for producing turbulence in vascular blood flow are provided. In practicing the subject methods, a blood flow modulator is positioned on an external site of a blood vessel at a location in relation to, e.g., at least proximal to a branched vascular site in a manner sufficient to produce turbulence in blood flow at a target site, e.g., at or immediately proximal to the branched vascular site. Representative blood flow modulation devices that find use in the subject methods are devices that can be positioned on an external site of a blood vessel to produce an annular structure around the blood vessel, where the annular structure includes an inner surface protuberance of sufficient dimensions to produce turbulence in the blood vessel. Also provided are kits and systems for practicing the subject methods. The subject methods and devices find use in a variety of applications, including applications to reduce the risk of emboli entering branch blood vessels from a main blood vessel.

Abstract: In an electric system that controls electrical or state variable devices through inputs received from device operators such as switches, buttons and the like, where some of the button control or set sequences for the electrical devices and others predefined “presets”, an automatic sequence tracking process monitors the system and adjusts the position of the sequence steps for buttons that are associated therewith, to ensure that they always track the current condition of the electrical devices. Thereby, actuation of sequence generating buttons will always choose the next step in a sequence for the corresponding electrical device.

Abstract: A control system includes a processor transmitting signals to a shade network and a lighting system directing that motorized shades and dimmable loads be set to desired intensity levels. A communication interface having a buffer is connected between the processor and the shade network. The communication interface provides for communication with the processor based on streaming protocol and with the shade network based on event-based protocol. The shade network converts intensity levels into shade positions. The processor may direct the shade network to move a shade in a series of substantially equal steps to simulate a relatively slowly moving shade. The processor may be connected to a timing device for creating a program based on time-based shade position information for directing the shades to be moved to given positions at certain times of day. A computer running user interface software may be be connected to the system to facilitate programming.

Abstract: Methods and devices for selectively removing an agent from a physiological efferent fluid collection site are provided. A feature of the invention is that a non-occlusive aspiration device is employed to selectively remove the target agent from the site only when the target agent is present in the site. Also provided are systems and kits for performing the subject methods. The subject invention finds use in a variety of different applications, including the selective removal of both therapeutic and diagnostic agents from a variety of different physiological sites.

Abstract: The control of fluid introduction into and out of body conduits such as vessels, is of great concern in medicine. As the development of more particular treatments to vessels and organs continues it is apparent that controlled introduction and removal of fluids is necessary. Fluid delivery and removal from such sites, usually referred to as irrigation and aspiration, using fluid exchange devices that control also need to be considerate of potential volume and/or pressure in the vessel or organ are described together with catheter and lumen configurations to achieve the fluid exchange. The devices include several electrically or mechanically controlled embodiments and produce both controlled and localized flow with defined volume exchange ratios for fluid management. The applications in medicine include diagnostic, therapeutic, imaging, and uses for the introduction or removal of concentrations of emboli within body cavities.

Abstract: In an electric system that controls electrical or state variable devices through inputs received from device operators such as switches, buttons and the like, where some of the buttons control or set sequences for the electrical devices and others predefined “presets”, an automatic sequence tracking process monitors the system and adjusts the position of the sequence steps for buttons that are associated therewith, to ensure that they always track the current condition of the electrical devices. Thereby, actuation of sequence generating buttons will always choose the next step in a sequence for the corresponding electrical device.

Abstract: The control of fluid introduction into and out of body conduits such as vessels, is of great concern in medicine. As the development of more particular treatments to vessels and organs continues it is apparent that controlled introduction and removal of fluids is necessary. Fluid delivery and removal from such sites, usually referred to as irrigation and aspiration, using fluid exchange devices that control also need to be considerate of potential volume and/or pressure in the vessel or organ are described together with catheter and lumen configurations to achieve the fluid exchange. The devices include several electrically or mechanically controlled embodiments and produce both controlled and localized flow with defined volume exchange ratios for fluid management. The applications in medicine include diagnostic, therapeutic, imaging, and uses for the introduction or removal of concentrations of emboli within body cavities.

Abstract: Apparatus and methods are described for effective removal of emboli or harmful fluids during vascular procedures, such as angiography, balloon angioplasty, stent deployment, laser angioplasty, atherectomy, intravascular ultrasonography and other therapeutic and diagnostic procedures. A catheter with an occluder mounted at its distal end creates an occlusion proximal to the lesion. The catheter provides a pathway for introducing a treatment catheter. Prior to, during or subsequent to the procedure, suction is activated to establish retrograde flow to remove emboli from the site. Additionally, a thin catheter with a distal fluid ejection nozzle may be introduced distal to the treatment site to rinse emboli from the treatment site. The suction flow and/or ejected fluid flow may be varied in a pulsatile manner to simulate regular blood flow and/or perturb settled emboli into being captured that may otherwise not be collected.