Patents by Inventor Brian Cunniff

Brian Cunniff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VITAMIN E AND CANCER THERAPEUTIC COMPOSITIONS AND METHODS
    Publication number: 20220080025
    Abstract: The invention relates, in part, to compounds, compositions, and methods useful to treat cancer in cells and subjects. The invention relates, in part, to compounds, compositions, and methods useful to treat cancer in cells and subjects. According to one aspect of the invention, methods for reducing cell viability in a population cells comprising cancer cells are provided, the methods including: contacting a population of cells that include cancer cells with Thiostrepton (TS) and Vitamin E-TPGS, under conditions and for a period of time sufficient for a statistically significant reduction in viability in a plurality of the cancer cells.
    Type: Application
    Filed: January 6, 2020
    Publication date: March 17, 2022
    Inventors: Brian CUNNIFF, Gregory FRYKMAN, Kimberly Johnson NELSON
  • CANCER THERAPEUTIC COMPOSITIONS AND METHODS
    Publication number: 20220072089
    Abstract: The invention relates, in part, to compounds, compositions, and methods comprising Thiostreopton (TS) that are useful to treat cancer in cells and subjects.
    Type: Application
    Filed: December 19, 2019
    Publication date: March 10, 2022
    Applicant: University of Vermont and State Agricultural College
    Inventors: Brian CUNNIFF, Nicholas HEINTZ, Terri MESSIER
  • DIRECT ASSAY OF THIOREDOXIN REDUCTASE ACTIVITY
    Publication number: 20150050682
    Abstract: Provided is a direct method for detecting thioredoxin reductase (TR) activity in test samples. The method can provide a continuous and real-time measurement of TR activity. The method comprises contacting the test sample with NADPH and a diselenide substrate of TR, and then measuring conversion of NADPH to NADP. Also provided are kits for use in the method of direct detection of TR activity.
    Type: Application
    Filed: August 15, 2014
    Publication date: February 19, 2015
    Inventors: Robert J. Hondal, Nicholas H. Heintz, Brian Cunniff, Nicholas Fredette, Gregg W. Snider