Abstract: Disclosed herein are novel chromogenic conjugates, the conjugates comprising at least two detectable moieties.

Abstract: Disclosed are compositions and methods for inactivating one or more enzymes in a biological sample.

Abstract: Disclosed herein are novel chromogenic conjugates, the conjugates comprising at least two detectable moieties.

Abstract: Systems-and methods for automated control of human inhabited characters. In an example, control of human inhabited character may be achieved via a plurality of input devices, including, but not limited to, a microphone, a camera, or a hand-held controller, that can modify and trigger changes in the appearance and/or the behavioral response of a character during the live interactions with humans. In an example, a computing device may include a neural network that receives the input from the microphone and/or the camera and changes the appearance and/or the behavioral response of the character according to the input. Further, input from the hand-held controller may be used to adjust a mood of the character or, in other words, emphasize or deemphasize the changes to the appearance and/or the behavioral response of the character.

Abstract: Disclosed herein are caged haptens and caged hapten-antibody conjugates useful for enabling the detection of targets located proximally to each other in a sample.

Abstract: Applicants have developed an amplification system and methodology for IHC and ISH staining that utilizes “click chemistry” to covalently bind reporter molecules to tissue.

Abstract: Disclosed herein are novel chromogenic conjugates, the conjugates comprising at least two detectable moieties.

Abstract: A control system provides an interface for virtual characters, or avatars, during live avatar-human interactions. A human interactor can select facial expressions, poses, and behaviors of the virtual character using an input device mapped to menus on a display device.

Abstract: Disclosed herein are methods for detecting the presence and/or amount of HER2 protein, HER2 nucleic acid (for example, HER2 genomic DNA), ER protein, and Chromosome 17 centromere DNA in a single sample. Samples stained for HER2 protein, HER2 DNA, ER protein, and Chromosome 17 DNA allow for the identification of various types of cancer cells, for example HER2 protein positive/ER protein positive/HER2 gene positive cells, HER2 protein positive/ER protein negative/HER2 gene positive cells, HER2 protein negative/ER protein positive/HER2 gene positive cells, and HER2 protein negative/ER protein negative/HER2 gene positive cells.

Abstract: Disclosed embodiments concern a composition comprising DAB chromogen, and/or derivative thereof, a stabilizer, and polymer capable of preventing or reducing DAB precipitation relative to a composition that does not comprise the polymer. Also disclosed herein is a method for using the disclosed composition and embodiments of a kit.

Abstract: A method for dispensing a beverage container to a consumer. The method includes receiving in a beverage container dispenser a first beverage container that contains a beverage corresponding to a beverage selection of a user. The method further includes dispensing a second beverage container containing the beverage from a temperature-regulated compartment of the beverage container dispenser. The second beverage container that is dispensed from the temperature-regulated compartment corresponds to the beverage selection of the user.

Abstract: Disclosed embodiments concern a composition comprising DAB chromogen, and/or derivative thereof, a stabilizer, and polymer capable of preventing or reducing DAB precipitation relative to a composition that does not comprise the polymer. Also disclosed herein is a method for using the disclosed composition and embodiments of a kit.

Abstract: Slush beverage dispensers and methods for providing slush beverages to consumers. The method for providing a slush beverage to a consumer may include storing in a temperature regulated compartment a beverage container containing a beverage at a predetermined temperature at or below a freezing point of the beverage without consumer access to the beverage container. The slush beverage dispenser may receive a consumer selection for a beverage. Based on the consumer selection, the slush beverage dispenser may agitate the beverage container such that the beverage within the beverage container undergoes nucleation. After agitation, the slush beverage dispenser may provide the beverage container to the consumer.

Abstract: A control system provides an interface for virtual characters, or avatars, during live avatar-human interactions. A human interactor can select facial expressions, poses, and behaviors of the virtual character using an input device mapped to menus on a display device.

Abstract: A control system provides an interface for virtual characters, or avatars, during live avatar-human interactions. A human interactor can select facial expressions, poses, and behaviors of the virtual character using an input device mapped to menus on a display device.

Abstract: Disclosed herein are caged haptens and caged hapten-antibody conjugates useful for enabling the detection of targets located proximally to each other in a sample.

Abstract: Applicants have developed an amplification system and methodology for IHC and ISH staining that utilizes “click chemistry” to covalently bind reporter molecules to tissue.

Abstract: Disclosed herein are novel chromogenic conjugates, the conjugates comprising at least two detectable moieties.

Abstract: Disclosed herein are novel quinone methide analog precursors and embodiments of a method and a kit of using the same for detecting one or more targets in a biological sample. The method of detection comprises contacting the sample with a detection probe, then contacting the sample with a labeling conjugate that comprises an enzyme. The enzyme interacts with a quinone methide analog precursor comprising a detectable label, forming a reactive quinone methide analog, which binds to the biological sample proximally to or directly on the target. The detectable label is then detected. In some embodiments, multiple targets can be detected by multiple quinone methide analog precursors interacting with different enzymes without the need for an enzyme deactivation step.

Abstract: Disclosed herein are novel quinone methide analog precursors and embodiments of a method and a kit of using the same for detecting one or more targets in a biological sample. The method of detection comprises contacting the sample with a detection probe, then contacting the sample with a labeling conjugate that comprises an enzyme. The enzyme interacts with a quinone methide analog precursor comprising a detectable label, forming a reactive quinone methide analog, which binds to the biological sample proximally to or directly on the target. The detectable label is then detected. In some embodiments, multiple targets can be detected by multiple quinone methide analog precursors interacting with different enzymes without the need for an enzyme deactivation step.