Patents by Inventor Brian Down

Brian Down has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydraulic Turbine Between Middle and Cold Bundles of Natural Gas Liquefaction Heat Exchanger
    Publication number: 20180283773
    Abstract: A system and method for liquefying a natural gas stream, including a liquefaction heat exchanger having at least three cooling bundles and arranged such that the natural gas stream passes sequentially therethrough. A first cooling bundle condenses heavy hydrocarbon components in the natural gas stream. A second cooling bundle liquefies the natural gas stream. A third cooling bundle sub-cools the LNG stream. A hydraulic turbine has an inlet operationally connected to an outlet of the second cooling bundle, and an outlet operationally connected to an inlet of the third cooling bundle. The hydraulic turbine cools the LNG stream and reduces the pressure of the LNG stream to form a reduced-pressure LNG stream.
    Type: Application
    Filed: February 23, 2018
    Publication date: October 4, 2018
    Inventors: Suhas P. Mondkar, O. Angus Sites, Steve Wright, Brian Downs
  • Granule formation
    Patent number: 8007830
    Abstract: The present invention relates to oral granules of montelukast sodium.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: August 30, 2011
    Assignee: Merck Frosst Canada & Co.
    Inventor: Brian Down
  • Granule formation
    Publication number: 20080131516
    Abstract: The present invention relates to oral granules of montelukast sodium.
    Type: Application
    Filed: February 7, 2008
    Publication date: June 5, 2008
    Inventor: Brian Down
  • Granule formulation
    Publication number: 20030096840
    Abstract: The present invention relates to oral granules of montelukast sodium.
    Type: Application
    Filed: October 24, 2002
    Publication date: May 22, 2003
    Inventor: Brian Down
  • Amorphous (quinolin-2-ylmethoxy)indole compounds useful for treating inflammatory diseases
    Patent number: 5321033
    Abstract: A form of 3-[N-(p-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl]- 2,2-dimethylpropanoic acid sodium salt, obtained by freeze or spray drying, is more soluble in water than the crystalline form thereof. The compound is useful as an anti-asthmatic, anti-allergic, anti-inflammatory, or cytoprotective agent. It is also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.
    Type: Grant
    Filed: July 26, 1993
    Date of Patent: June 14, 1994
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Brian Down, John H. Hutchinson
  • Amorphous (quinolin-2-ylmethoxy)indole compounds which have useful pharmaceutical utility
    Patent number: 5254567
    Abstract: A form of 3-[N-(p-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl]- 2,2-dimethylpropanoic acid sodium salt, obtained by freeze or spray drying, is more soluble in water than the crystalline form thereof. The compound is useful as an anti-asthmatic, anti-allergic, anti-inflammatory, or cytoprotective agent. It is also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.
    Type: Grant
    Filed: November 9, 1992
    Date of Patent: October 19, 1993
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Brian Down, John H. Hutchinson