Patents by Inventor Brian M. Cali

Brian M. Cali has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatments for gastrointestinal disorders
    Patent number: 9617305
    Abstract: The present invention provides pharmaceutical compositions and methods of treating lower gastrointestinal disorders, including inflammatory bowel disease (IBD), diverticulitis, colon cancer, an inflammatory disorder, obesity, congestive heart failure, benign prostatic hyperplasia (BPH), pain, salt retention or fluid retention.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: April 11, 2017
    Assignee: Ironwood Pharmaceuticals, Inc.
    Inventors: Mark G. Currie, Daniel P. Zimmer, Angelika Fretzen, Marco Kessler, Brian M. Cali
  • Treatments for gastrointestinal disorders
    Patent number: 9527887
    Abstract: The present invention provides pharmaceutical compositions and methods of treating lower gastrointestinal disorders, including irritable bowel syndrome and constipation.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: December 27, 2016
    Assignee: Ironwood Pharmaceutical, Inc.
    Inventors: Mark G. Currie, Daniel P. Zimmer, Angelika Fretzen, Marco Kessler, Brian M. Cali
  • Treatments for Gastrointestinal Disorders
    Publication number: 20140348942
    Abstract: The present invention provides pharmaceutical compositions and methods of treating lower gastrointestinal disorders, including inflammatory bowel disease (IBD), diverticulitis, colon cancer, an inflammatory disorder, obesity, congestive heart failure, benign prostatic hyperplasia (BPH), pain, salt retention or fluid retention.
    Type: Application
    Filed: June 8, 2012
    Publication date: November 27, 2014
    Applicant: Ironwood Pharmaceuticals, Inc.
    Inventors: Mark G. Currie, Daniel P. Zimmer, Angelika Fretzen, Marco Kassler, Brian M. Cali
  • Treatments for Gastrointestinal Disorders
    Publication number: 20140342996
    Abstract: The present invention provides pharmaceutical compositions and methods of treating lower gastrointestinal disorders, including irritable bowel syndrome and constipation.
    Type: Application
    Filed: June 8, 2012
    Publication date: November 20, 2014
    Applicant: Ironwood Pharmaceuticals, Inc.
    Inventors: Mark G. Currie, Daniel P. Zimmer, Angelika Fretzen, Marco Kessler, Brian M. Cali
  • Useful indole compounds
    Patent number: 7960544
    Abstract: Indoles that have activity as inhibitors of FAAH are described as are indoles and indole derivatives that have activity as inhibitors of DAO.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: June 14, 2011
    Assignee: Ironwood Pharmaceuticals, Inc.
    Inventors: Wilmin Bartolini, Brian M. Cali, Barbara Chen, Yueh-Tyng Chien, Mark G. Currie, G. Todd Milne, James Philip Pearson, John Jeffrey Talley, Jane Yang, Craig Zimmerman, Charles Kim, Kevin Sprott, Timothy Barden, Regina Lundigran, Ara Mermerian
  • USEFUL INDOLE COMPOUNDS
    Publication number: 20090264653
    Abstract: Indoles that have activity as inhibitors of FAAH are described as are indoles and indole derivatives that have activity as inhibitors of DAO.
    Type: Application
    Filed: December 18, 2006
    Publication date: October 22, 2009
    Inventors: Wilmin Bartolini, Brian M Cali, Barbara Chen, Yueh-Tyng Chien, Mark G. Currie, G. Todd Milne, James Philip Pearson, John Jeffrey Talley, Jane Yang, Craig Zimmerman, Charles Kim, Kevin Sprott, Timothy Barden, Regina Lundigran, Ara Mermerian
  • Modulators of CRTH2 activity
    Patent number: 7205329
    Abstract: Modulators of the CRTH2 receptor and their use in the treatment of various disorders, including asthma are described.
    Type: Grant
    Filed: July 18, 2005
    Date of Patent: April 17, 2007
    Assignee: Microbia, Inc.
    Inventors: Yueh-Tyng Chien, G. Todd Milne, Mark G. Currie, John Jeffrey Talley, Brian M. Cali, Barbara Chen, Craig Zimmerman, Jing Jing Yang
  • Isolated nucleic acid molecule encoding a regulator of fungal gene expression
    Patent number: 6806082
    Abstract: The invention relates to regulators of fungal gene expression and their use in commercial and medical applications. More particularly, the invention relates to regulators of fungal genes involved in production of enzymes, secondary metabolites and other useful products, as well as to regulators of genes involved in fungal invasion. The invention provides novel regulators of fungal gene expression, and methods for using regulator genes in commercial and medical applications.
    Type: Grant
    Filed: December 22, 2001
    Date of Patent: October 19, 2004
    Assignee: Microbia, Inc.
    Inventors: Brian M. Cali, Douglas Holtzman, Kevin T. Madden, G. Todd Milne, Amir Sherman, Jeffrey C. Silva, Joshua Trueheart, Lixin Zhang
  • Novel regulators of fungal gene expression
    Publication number: 20020182708
    Abstract: The invention relates to regulators of fungal gene expression and their use in commercial and medical applications. More particularly, the invention relates to regulators of fungal genes involved in production of enzymes, secondary metabolites and other useful products, as well as to regulators of genes involved in fungal invasion. The invention provides novel regulators of fungal gene expression, and methods for using regulator genes in commercial and medical applications.
    Type: Application
    Filed: December 22, 2001
    Publication date: December 5, 2002
    Inventors: Brian M. Cali, Douglas Holtzman, Kevin T. Madden, G. Todd Milne, Amir Sherman, Jeffrey C. Silva, Joshua Trueheart, Lixin Zhang