Patents by Inventor Brian Matthew Hoyland

Brian Matthew Hoyland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorescent conjugates of metal-chelating nitrogen heterocycles
    Patent number: 6013802
    Abstract: The present invention describes a family of fluorescent indicators for metal cations. The indicators are fluorophore conjugates of pyridyl-based metal ion chelators. The indicators are very sensitive detection as quantification reagents for a variety of metals, in a variety of oxidation states, even in the presence of high concentrations of Ca.sup.2+, Na.sup.+, or K.sup.+ or other ions, such as is found in seawater, making them highly useful for assaying physiological samples, biological samples, or environmental samples.
    Type: Grant
    Filed: February 7, 1997
    Date of Patent: January 11, 2000
    Assignee: Molecular Probes, Inc.
    Inventors: Brian Matthew Hoyland, Michael A. Kuhn, Richard P. Haugland
  • Methods of sensing with fluorescent conjugates of metal-chelating nitrogen heterocycles
    Patent number: 5648270
    Abstract: The present invention describes the use of a family of fluorescent indicators for metal cations. The indicators are fluorophore conjugates of pyridyl-based metal ion chelators. The indicators are very sensitive detection as quantification reagents for a variety of metals, in a variety of oxidation states, even in the presence of high concentrations of Ca.sup.2+, Na.sup.+, or K.sup.+ or other ions, such as is found in seawater, making them highly useful for assaying physiological samples, biological samples, or environmental samples.
    Type: Grant
    Filed: February 6, 1995
    Date of Patent: July 15, 1997
    Assignee: Molecular Probes, Inc.
    Inventors: Michael A. Kuhn, Richard P. Haugland, Brian Matthew Hoyland