Abstract: Disclosed are dendrimers of formula (I): and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising the dendrimer of formula (I) and methods of using the same for treating cancer.

Abstract: A timing adjustment assembly for a compound archery bow is provided. The timing adjustment assembly is coupled with a pulley assembly and power cable of the archery bow. The timing adjustment assembly includes an adjustable component and a stationary component. The stationary component is attached to either the pulley assembly, the power cable, or the riser of the archery bow. The adjustable component is configured to move in a linear direction between multiple positional arrangements relative to the stationary component. The movement of the adjustable component changes the effective length of the power cable by moving the termination anchor point of the power cable or deflecting the power cable. The timing adjustment assembly adjusts the effective length of the power cable and relative synchronization of the pulley assembly with the archery bow in a brace position through the change in termination anchor point or deflection.

Abstract: An apparatus (10) for preserving biological material. The apparatus (10) has an insert (4) configured to be arranged within an outer insulated tank (2), the insert (4) defining a compartment (6) for receiving biological material. Inflow of a heat exchange fluid into the compartment (6) from the outer insulated tank (2) is at or adjacent one face of the insert (4), while outflow of the heat exchange fluid out of the compartment 6 to the outer insulated tank (2) is at or adjacent said face of the insert (4). The compartment (6) has a wall having a series of apertures to accommodate a continuous heat exchange fluid flow through the apparatus such that, in operation, biological material in the compartment (6) is immersed in the heat exchange fluid to exchange heat with the heat exchange fluid for freezing of said biological material.

Abstract: A distributed database receives an instruction to read or write data. The instruction includes a key. The database includes a key space defined by attoshards. An attoshard is a segment of key space having a size, in keys, proportional to a total number of nodes in the database. The attoshard includes keys for cluster segments at predefined positions in the attoshard. Each cluster segment corresponds to one cluster. A node of the database hashes the key to generate a token. The node performs a modulo operation on the token using the total number of nodes in the database to compute a remainder value. The node determines a cluster segment of an attoshard based on a position in the attoshard defined by the remainder value. The node determines a cluster for the instruction based on the cluster segment and executes the instruction at the determined cluster.

Abstract: A distributed database receives an instruction to read or write data. The instruction includes a key. The database includes a key space defined by attoshards. An attoshard is a segment of key space having a size, in keys, proportional to a total number of nodes in the database. The attoshard includes keys for cluster segments at predefined positions in the attoshard. Each cluster segment corresponds to one cluster. A node of the database hashes the key to generate a token. The node performs a modulo operation on the token using the total number of nodes in the database to compute a remainder value. The node determines a cluster segment of an attoshard based on a position in the attoshard defined by the remainder value. The node determines a cluster for the instruction based on the cluster segment and executes the instruction at the determined cluster.

Abstract: A product testing assembly is described. The product testing assembly may include a substrate, at least one measuring device, and at least one data processing system. The substrate has at least one surface configured to receive an application of a product to be tested. The at least one measuring device is configured to sense measured quantities as product is applied to the substrate and output one or more signals representative of a sequence of forces and/or moments being applied to the surface of the substrate by the application of the product to be tested. The at least one data processing system has one or more processors configured to receive the one or more signals representative of the sequence of forces and/or moments being applied to the surface of the substrate, and to convert the one or more signals into an output signal representative of one or more application performance characteristics of the product to be tested.

Abstract: A train brake tool for engaging and disengaging a train brake, such as a brake wheel or lever, is described. The train brake tool is configured for manual or hand operation and has both a puller portion and pusher portion configured at the end of an elongated member. The puller portion is configured with a hook for insertion into an opening in a brake wheel to allow the user to pull and rotate the wheel. The pusher portion has a hook configured oppositely to the puller, to allow the user to push the wheel. A length extension is described and is configured to be detachably attachable to the train brake tool.

Abstract: A product testing assembly is described. The product testing assembly may include a substrate, at least one measuring device, and at least one data processing system. The substrate has at least one surface configured to receive an application of a product to be tested. The at least one measuring device is configured to sense measured quantities as product is applied to the substrate and output one or more signals representative of a sequence of forces and/or moments being applied to the surface of the substrate by the application of the product to be tested. The at least one data processing system has one or more processors configured to receive the one or more signals representative of the sequence of forces and/or moments being applied to the surface of the substrate, and to convert the one or more signals into an output signal representative of one or more application performance characteristics of the product to be tested.

Abstract: The present invention related to a door jamb finger guard. The finger guard comprises a door lock for preventing closure of the door, a housing for the door lock and a spring activated plate. The spring activated plate is activateable by a door closing obstacle for automatically moving the door lock between an inactive position and an active position. In the inactive position, the door lock is recessed within the housing, while in the active position, the door lock projects from the housing to prevent closure of the door.

Abstract: Conflict resolution of web application keyboard shortcuts implementation includes a web application being loaded in a web browser and application keyboard shortcuts for the web application are registered with the web browser. The web browser identifies application keyboard shortcuts for the web application that conflict with keyboard shortcuts for the web browser. Then the web browser resolves each conflict.

Abstract: In an embodiment, a sentence is created that describes a walk of a graph. The graph includes a set of nodes and a set of edges that are incident to the nodes. The sentence includes label words that describe the nodes and relationship words that describe the edges. The walk is an alternating sequence of a subset of the nodes and of the edges. Each of the edges in the walk is incident to two of the nodes that precede and follow the respective edge. The sentence is created by determining a parent node associated with a selected label word, determining the child nodes of the parent node, determining the edges that are incident to the parent nodes and the child nodes, determining relationship words that describe the edges that are incident to the parent nodes and the child nodes, and determining child label words that describe the child nodes. A selected relationship word and a selected child label word are then added to the sentence. In this way, a walk of the graph may be more easily understood.

Abstract: A method, apparatus and computer program product are provided for implementing enhanced install performance of a computer system. A user request for an update to be installed is identified. The update to be installed is described by metadata. An installer is provided for installing one or multiple updates. Predefined information for each update to be installed, including any pre-installation operation and post-installation operation required by each update, is processed to provide enhanced install performance.

Abstract: An apparatus and method are described for displaying a topological graph that allows a user to navigate through a history of previous topology displays to increase the user's understanding and awareness of the state of the topology. In a preferred embodiment, a topology display mechanism receives state changes to a topology of a computer network and stores a sequence of graphs that reflect the changes that are made to the topology. The topology display mechanism also allows the user to step through the sequence of stored topology graphs using “video” type controls to change the display of the topology graphs. In other embodiments, the topology display mechanism displays the changes in the topology as a sequence of graphs that form an animation to give the user a graphical visualization of the changes from one topology graph in the sequence to the next.

Abstract: A page is received, which includes elements. A tree represents the page. A subset of the elements are displayed. In response to selection of an important element, a subtree is created, which includes a path from a root element of the tree to the important element. A changed page is received, which is represented by a changed tree. A second path in the changed tree is found, where a leaf element of the second path is different from the important element in the first path, and where all other elements in the first path and the second path match. A message is displayed, which indicates that the important element was changed. In various embodiments, the message is presented in audio, magnified, or touch form. In this way, the user is notified of changes to the page that the user has selected as important.

Abstract: The present invention relates to a door jamb finger guard. The finger guard comprises a door lock for preventing closure of the door, a housing for the door lock and an activating means. The activating means is activateable by a door closing obstacle for automatically moving the door lock between an inactive position and an active position. In the inactive position, the door lock is recessed within the housing, while in the active position, the door lock projects from the housing to prevent closure of the door.

Abstract: Conflict resolution of web application keyboard shortcuts implementation includes a web application being loaded in a web browser and application keyboard shortcuts for the web application are registered with the web browser. The web browser identifies application keyboard shortcuts for the web application that conflict with keyboard shortcuts for the web browser. Then the web browser resolves each conflict.

Abstract: An apparatus and method are described for displaying a topological graph that allows a user to navigate through a history of previous topology displays to increase the user's understanding and awareness of the state of the topology. In a preferred embodiment, a topology display mechanism receives state changes to a topology of a computer network and stores a sequence of graphs that reflect the changes that are made to the topology. The topology display mechanism also allows the user to step through the sequence of stored topology graphs using “video” type controls to change the display of the topology graphs. In other embodiments, the topology display mechanism displays the changes in the topology as a sequence of graphs that form an animation to give the user a graphical visualization of the changes from one topology graph in the sequence to the next.

Abstract: A method of operating an imaging apparatus having a duplexer and a perforation device for processing a sheet of media having a first surface and a second surface opposite to the first surface includes forming an image on the first surface of the sheet of media; advancing the sheet of media through the duplexer; and forming a plurality of close-spaced perforations on the sheet of media from the second surface toward the first surface.

Abstract: An apparatus for perforating a sheet of media includes a perforation forming mechanism including at least one perforation device. The perforation forming mechanism is configured to drive the perforation device through the sheet of media to extend through the sheet of media by a distance.

Abstract: An apparatus for perforating a sheet of media includes a perforation forming mechanism including at least one perforation device. The perforation forming mechanism is configured to drive the perforation device through the sheet of media to extend through the sheet of media by a distance.