Patents by Inventor Brian Poligone

Brian Poligone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF PREVENTING DEVELOPMENT OF PSORIATIC LESIONS
    Publication number: 20140296154
    Abstract: The present invention relates to a method of inhibiting onset of or preventing development of a psoriatic lesion in a patient having psoriasis. The method comprises administering to a patient having psoriasis an effective amount of an agent that inhibits NF-?B activity under conditions effective to inhibit onset of or prevent development of psoriatic lesions. Another aspect of the invention relates to a method of treating an early stage psoriatic lesion on a patient by contacting the early stage psoriatic lesion of a patient with an effective amount of an agent that inhibits NF-?B activity, whereby said contacting inhibits development of the early stage psoriatic lesion. Both transgenic and nontransgenic approaches are contemplated.
    Type: Application
    Filed: May 7, 2012
    Publication date: October 2, 2014
    Applicants: YALE UNIVERSITY, UNIVERSITY OF ROCHESTER
    Inventors: Brian Poligone, Sankar Ghosh
  • Methods for preventing GVHD
    Publication number: 20040166095
    Abstract: Methods are provided for administering alloreactive T cells to transplant recipients such that the risk of graft-versus-host disease is reduced.
    Type: Application
    Filed: February 25, 2003
    Publication date: August 26, 2004
    Inventors: Bruce R. Blazar, Matthew J. O'Shaughnessy, Christine Vogtenhuber, Jonathan S. Serody, Albert S. Baldwin, Brian Poligone