Patents by Inventor Brian R. C. Theobald

Brian R. C. Theobald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Invitroinhibition of the HIV virus with ionic tungstoniobate compounds
    Patent number: 5512305
    Abstract: Tungstoniobate compounds containing an ion of general formulaA.sub.x W.sub.y Nb.sub.a O.sub.b !.sup.p- Iwhere A=P, Si, Ge, x=0 or an integer from 1 to 10, y is an integer from 1 to 10, y is an integer from 1 to 40, a is an integer from 1 to 8, b is an integer from 15 to 150, and p is an integer dependent upon the nature and oxidation state of element A, have been found to be active against viruses including especially HIV and Herpes Simplex. Pharmaceutical compositions and methods of treatment are disclosed.
    Type: Grant
    Filed: August 26, 1993
    Date of Patent: April 30, 1996
    Inventors: Michael J. Abrams, Gerald E. Bossard, Craig L. Hill, Raymond F. Schinazi, Brian R. C. Theobald
  • Method of treating HIV infection using polyoxometallates
    Patent number: 5093134
    Abstract: Compounds of the formula,A.sub.x [D'(MW.sub.11 O.sub.39).sub.2 ].multidot.yH.sub.2 Oin which A is a cation, x is an integer, M is B, Si or P, D is metal and D' is a lanthanide in oxidation state 3 or 4, L is a neutral or anionic ligand, and y is an interger, have anti-viral activity in a standard screen, and may be used to produce compositions and also coated articles and devices for treatment or prophylactic treatment of patients at risk.
    Type: Grant
    Filed: March 14, 1990
    Date of Patent: March 3, 1992
    Assignee: Johnson Matthey Public Limited Company
    Inventors: Barry A. Murrer, Brian R. C. Theobald, Paul D. Savage