Patents by Inventor Brian T. Grimberg

Brian T. Grimberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11982638
    Abstract: A diagnostic device is described herein that can be used to perform magneto-optical detection and discernment of crystals within a biofluid sample. A magnetic field can be applied by the diagnostic device in a direction relative to light traveling through the sample. The presence of a crystal can be determined based on the magneto-optical properties of the sample. The detected crystal can be one of two similar crystal types that may be in the biofluid sample. The two similar crystal types can exhibit different magneto-optical properties under a magnetic field in a different direction. Accordingly, the type of crystal can be discerned by applying the magnetic field in the different direction as light travels through the sample. Discernment of the type of crystal can lead to diagnosis of the particular disease condition and subsequent proper treatment of the disease condition.
    Type: Grant
    Filed: June 8, 2022
    Date of Patent: May 14, 2024
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Tanvir Baig, Robert Brown, Robert Deissler, Brian T. Grimberg, Abdullah Amin
  • Publication number: 20230309874
    Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.
    Type: Application
    Filed: June 6, 2023
    Publication date: October 5, 2023
    Inventors: Peter GALEN, Umut Atakan GURKAN, Arwa FRAIWAN, Muhammad Noman Hasan, Daniel E. Grupp, Joshua King Hoyt, James Thorne, Brian T. Grimberg
  • Patent number: 11701039
    Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: July 18, 2023
    Assignee: HEMEX HEALTH, INC.
    Inventors: Peter Galen, Umut Gurkan, Arwa Fraiwan, Muhammad Noman Hasan, Daniel E. Grupp, Joshua King Hoyt, James Thorne, Brian T. Grimberg
  • Patent number: 11656220
    Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as a magneto-optical system that measures a light transmission differential through the patient sample in varying magnetic fields. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disease, infection and/or condition of the patient.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: May 23, 2023
    Assignee: HEMEX HEALTH, INC.
    Inventors: Peter Galen, David John Sayler, Joshua King Hoyt, Daniel E. Grupp, Brian T. Grimberg, Umut Atakan Gurkan
  • Publication number: 20220299475
    Abstract: A diagnostic device is described herein that can be used to perform magneto-optical detection and discernment of crystals within a biofluid sample. A magnetic field can be applied by the diagnostic device in a direction relative to light traveling through the sample. The presence of a crystal can be determined based on the magneto-optical properties of the sample. The detected crystal can be one of two similar crystal types that may be in the biofluid sample. The two similar crystal types can exhibit different magneto-optical properties under a magnetic field in a different direction. Accordingly, the type of crystal can be discerned by applying the magnetic field in the different direction as light travels through the sample. Discernment of the type of crystal can lead to diagnosis of the particular disease condition and subsequent proper treatment of the disease condition.
    Type: Application
    Filed: June 8, 2022
    Publication date: September 22, 2022
    Inventors: Tanvir Baig, Robert Brown, Robert Deissler, Brian T. Grimberg, Abdullah Amin
  • Patent number: 11408854
    Abstract: A diagnostic device is described herein that can be used to perform magneto-optical detection and discernment of crystals within a biofluid sample. A magnetic field can be applied by the diagnostic device in a direction relative to light traveling through the sample. The presence of a crystal can be determined based on the magneto-optical properties of the sample. The detected crystal can be one of two similar crystal types that may be in the biofluid sample. The two similar crystal types can exhibit different magneto-optical properties under a magnetic field in a different direction. Accordingly, the type of crystal can be discerned by applying the magnetic field in the different direction as light travels through the sample. Discernment of the type of crystal can lead to diagnosis of the particular disease condition and subsequent proper treatment of the disease condition.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: August 9, 2022
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Tanvir Baig, Robert Brown, Robert Deissler, Brian T. Grimberg, Abdullah Amin
  • Publication number: 20220146491
    Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient. For example, the data collection and analysis can differentiate between two or more species capable of causing or actually causing a parasitic infection.
    Type: Application
    Filed: April 10, 2020
    Publication date: May 12, 2022
    Inventors: Peter GALEN, James Daren Bledsoe, Robert J. Deissler, D'Arbra Blankenship, Brian T. Grimberg
  • Publication number: 20210311016
    Abstract: A diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease or infection of the patient. For example, the data collection and analysis can determine one or more hemozoin characteristics.
    Type: Application
    Filed: June 22, 2021
    Publication date: October 7, 2021
    Inventors: Peter Galen, James Daren Bledsoe, D'Arbra Blankenship, Robert J. Deissler, Steven M. Goss, Brian T. Grimberg
  • Patent number: 11061014
    Abstract: A diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease or infection of the patient. For example, the data collection and analysis can determine one or more hemozoin characteristics.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: July 13, 2021
    Assignee: HEMEX HEALTH, INC.
    Inventors: Peter Galen, James Daren Bledsoe, D'Arbra Blankenship, Robert J. Deissler, Steven M. Goss, Brian T. Grimberg
  • Publication number: 20200408735
    Abstract: A diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease or infection of the patient. For example, the data collection and analysis can determine one or more hemozoin characteristics.
    Type: Application
    Filed: June 25, 2020
    Publication date: December 31, 2020
    Inventors: Peter Galen, James Daren Bledsoe, Brian T. Grimberg, D'Arbra Blankenship, Robert J. Deissler, Steven M. Goss
  • Publication number: 20200378946
    Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as a magneto-optical system that measures a light transmission differential through the patient sample in varying magnetic fields. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disease, infection and/or condition of the patient.
    Type: Application
    Filed: August 21, 2020
    Publication date: December 3, 2020
    Inventors: Peter GALEN, David John SAYLER, Joshua King HOYT, Daniel E. GRUPP, Brian T. GRIMBERG, Umut Atakan GURKAN
  • Patent number: 10768166
    Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as a magneto-optical system that measures a light transmission differential through the patient sample in varying magnetic fields. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disease, infection and/or condition of the patient.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: September 8, 2020
    Assignee: Hemex Health, Inc.
    Inventors: Peter Galen, David John Sayler, Joshua King Hoyt, Daniel E. Grupp, Brian T. Grimberg, Umut Atakan Gurkan
  • Publication number: 20190335696
    Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.
    Type: Application
    Filed: July 15, 2019
    Publication date: November 7, 2019
    Inventors: Peter GALEN, UMUT GURKAN, ARWA FRAIWAN, MUHAMMAD NOMAN HASAN, DANIEL E. GRUPP, JOSHUA KING HOYT, JAMES THORNE, BRIAN T. GRIMBERG
  • Patent number: 10375909
    Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: August 13, 2019
    Assignee: HEMEX HEALTH, INC.
    Inventors: Peter Galen, Umut Gurkan, Arwa Fraiwan, Muhammad Noman Hasan, Daniel E. Grupp, Joshua King Hoyt, James Thorne, Brian T. Grimberg
  • Patent number: 10349589
    Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: July 16, 2019
    Assignee: HEMEX HEALTH, INC.
    Inventors: Peter Galen, Umut Atakan Gurkan, Arwa Fraiwan, Muhammad Noman Hasan, Daniel E. Grupp, Joshua King Hoyt, James Thorne, Brian T. Grimberg
  • Publication number: 20190064113
    Abstract: A diagnostic device is described herein that can be used to perform magneto-optical detection and discernment of crystals within a biofluid sample. A magnetic field can be applied by the diagnostic device in a direction relative to light traveling through the sample. The presence of a crystal can be determined based on the magneto-optical properties of the sample. The detected crystal can be one of two similar crystal types that may be in the biofluid sample. The two similar crystal types can exhibit different magneto-optical properties under a magnetic field in a different direction. Accordingly, the type of crystal can be discerned by applying the magnetic field in the different direction as light travels through the sample. Discernment of the type of crystal can lead to diagnosis of the particular disease condition and subsequent proper treatment of the disease condition.
    Type: Application
    Filed: August 25, 2017
    Publication date: February 28, 2019
    Inventors: Tanvir Baig, Robert Brown, Robert Deissler, Brian T. Grimberg, Abdullah Amin
  • Publication number: 20190053454
    Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.
    Type: Application
    Filed: August 27, 2018
    Publication date: February 21, 2019
    Inventors: PETER GALEN, UMUT GURKAN, ARWA FRAIWAN, MUHAMMAD NOMAN HASAN, DANIEL E. GRUPP, JOSHUA KING HOYT, JAMES THORNE, BRIAN T. GRIMBERG
  • Publication number: 20180067101
    Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as a magneto-optical system that measures a light transmission differential through the patient sample in varying magnetic fields. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disease, infection and/or condition of the patient.
    Type: Application
    Filed: May 18, 2017
    Publication date: March 8, 2018
    Inventors: PETER GALEN, David John Sayler, Joshua King Hoyt, Daniel E. Grupp, Brian T. Grimberg, Umat Atakan Gurkan
  • Publication number: 20180064384
    Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.
    Type: Application
    Filed: September 8, 2017
    Publication date: March 8, 2018
    Inventors: PETER GALEN, UMUT ATAKAN GURKAN, ARWA FRAIWAN, MUHAMMAD NOMAN HASAN, DANIEL E. GRUPP, JOSHUA KING HOYT, JAMES THORNE, BRIAN T. GRIMBERG
  • Patent number: 9778245
    Abstract: A diagnostic device is provided that comprises a light source for transmitting a light beam through a blood sample to a light detector, and a permanent magnet, wherein one of the permanent magnet and blood sample is automatically movable relative to the other between a “HIGH” magnetic state position and a “LOW” magnetic state position, such that a substantially high magnetic field is applied to the blood sample causing any hemozoin in the blood sample to tend toward perpendicular orientation to the substantially magnetic field and the suppression, or enhancement of light based on its polarization, and a zero-to-near-zero magnetic field is applied to the blood sample causing the randomization of any hemozoin in the blood sample and a baseline amount of light to pass through the blood sample in the “LOW” magnetic state position.
    Type: Grant
    Filed: February 6, 2017
    Date of Patent: October 3, 2017
    Assignee: Case Western Reserve University
    Inventors: Brian T. Grimberg, Robert Deissler, William Condit, Robert Brown, Jason Jones, Richard Bihary