Patents by Inventor Brian T. Grimberg
Brian T. Grimberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11982638Abstract: A diagnostic device is described herein that can be used to perform magneto-optical detection and discernment of crystals within a biofluid sample. A magnetic field can be applied by the diagnostic device in a direction relative to light traveling through the sample. The presence of a crystal can be determined based on the magneto-optical properties of the sample. The detected crystal can be one of two similar crystal types that may be in the biofluid sample. The two similar crystal types can exhibit different magneto-optical properties under a magnetic field in a different direction. Accordingly, the type of crystal can be discerned by applying the magnetic field in the different direction as light travels through the sample. Discernment of the type of crystal can lead to diagnosis of the particular disease condition and subsequent proper treatment of the disease condition.Type: GrantFiled: June 8, 2022Date of Patent: May 14, 2024Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Tanvir Baig, Robert Brown, Robert Deissler, Brian T. Grimberg, Abdullah Amin
-
Publication number: 20230309874Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.Type: ApplicationFiled: June 6, 2023Publication date: October 5, 2023Inventors: Peter GALEN, Umut Atakan GURKAN, Arwa FRAIWAN, Muhammad Noman Hasan, Daniel E. Grupp, Joshua King Hoyt, James Thorne, Brian T. Grimberg
-
Patent number: 11701039Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.Type: GrantFiled: July 15, 2019Date of Patent: July 18, 2023Assignee: HEMEX HEALTH, INC.Inventors: Peter Galen, Umut Gurkan, Arwa Fraiwan, Muhammad Noman Hasan, Daniel E. Grupp, Joshua King Hoyt, James Thorne, Brian T. Grimberg
-
Patent number: 11656220Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as a magneto-optical system that measures a light transmission differential through the patient sample in varying magnetic fields. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disease, infection and/or condition of the patient.Type: GrantFiled: August 21, 2020Date of Patent: May 23, 2023Assignee: HEMEX HEALTH, INC.Inventors: Peter Galen, David John Sayler, Joshua King Hoyt, Daniel E. Grupp, Brian T. Grimberg, Umut Atakan Gurkan
-
Publication number: 20220299475Abstract: A diagnostic device is described herein that can be used to perform magneto-optical detection and discernment of crystals within a biofluid sample. A magnetic field can be applied by the diagnostic device in a direction relative to light traveling through the sample. The presence of a crystal can be determined based on the magneto-optical properties of the sample. The detected crystal can be one of two similar crystal types that may be in the biofluid sample. The two similar crystal types can exhibit different magneto-optical properties under a magnetic field in a different direction. Accordingly, the type of crystal can be discerned by applying the magnetic field in the different direction as light travels through the sample. Discernment of the type of crystal can lead to diagnosis of the particular disease condition and subsequent proper treatment of the disease condition.Type: ApplicationFiled: June 8, 2022Publication date: September 22, 2022Inventors: Tanvir Baig, Robert Brown, Robert Deissler, Brian T. Grimberg, Abdullah Amin
-
Patent number: 11408854Abstract: A diagnostic device is described herein that can be used to perform magneto-optical detection and discernment of crystals within a biofluid sample. A magnetic field can be applied by the diagnostic device in a direction relative to light traveling through the sample. The presence of a crystal can be determined based on the magneto-optical properties of the sample. The detected crystal can be one of two similar crystal types that may be in the biofluid sample. The two similar crystal types can exhibit different magneto-optical properties under a magnetic field in a different direction. Accordingly, the type of crystal can be discerned by applying the magnetic field in the different direction as light travels through the sample. Discernment of the type of crystal can lead to diagnosis of the particular disease condition and subsequent proper treatment of the disease condition.Type: GrantFiled: August 25, 2017Date of Patent: August 9, 2022Assignee: CASE WESTERN RESERVE UNIVERSITYInventors: Tanvir Baig, Robert Brown, Robert Deissler, Brian T. Grimberg, Abdullah Amin
-
Publication number: 20220146491Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient. For example, the data collection and analysis can differentiate between two or more species capable of causing or actually causing a parasitic infection.Type: ApplicationFiled: April 10, 2020Publication date: May 12, 2022Inventors: Peter GALEN, James Daren Bledsoe, Robert J. Deissler, D'Arbra Blankenship, Brian T. Grimberg
-
Publication number: 20210311016Abstract: A diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease or infection of the patient. For example, the data collection and analysis can determine one or more hemozoin characteristics.Type: ApplicationFiled: June 22, 2021Publication date: October 7, 2021Inventors: Peter Galen, James Daren Bledsoe, D'Arbra Blankenship, Robert J. Deissler, Steven M. Goss, Brian T. Grimberg
-
Patent number: 11061014Abstract: A diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease or infection of the patient. For example, the data collection and analysis can determine one or more hemozoin characteristics.Type: GrantFiled: June 25, 2020Date of Patent: July 13, 2021Assignee: HEMEX HEALTH, INC.Inventors: Peter Galen, James Daren Bledsoe, D'Arbra Blankenship, Robert J. Deissler, Steven M. Goss, Brian T. Grimberg
-
Publication number: 20200408735Abstract: A diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The sample can be processed for data collection and analysis to provide interpretative results indicative of a disorder, condition, disease or infection of the patient. For example, the data collection and analysis can determine one or more hemozoin characteristics.Type: ApplicationFiled: June 25, 2020Publication date: December 31, 2020Inventors: Peter Galen, James Daren Bledsoe, Brian T. Grimberg, D'Arbra Blankenship, Robert J. Deissler, Steven M. Goss
-
Publication number: 20200378946Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as a magneto-optical system that measures a light transmission differential through the patient sample in varying magnetic fields. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disease, infection and/or condition of the patient.Type: ApplicationFiled: August 21, 2020Publication date: December 3, 2020Inventors: Peter GALEN, David John SAYLER, Joshua King HOYT, Daniel E. GRUPP, Brian T. GRIMBERG, Umut Atakan GURKAN
-
Patent number: 10768166Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as a magneto-optical system that measures a light transmission differential through the patient sample in varying magnetic fields. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disease, infection and/or condition of the patient.Type: GrantFiled: May 18, 2017Date of Patent: September 8, 2020Assignee: Hemex Health, Inc.Inventors: Peter Galen, David John Sayler, Joshua King Hoyt, Daniel E. Grupp, Brian T. Grimberg, Umut Atakan Gurkan
-
Publication number: 20190335696Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.Type: ApplicationFiled: July 15, 2019Publication date: November 7, 2019Inventors: Peter GALEN, UMUT GURKAN, ARWA FRAIWAN, MUHAMMAD NOMAN HASAN, DANIEL E. GRUPP, JOSHUA KING HOYT, JAMES THORNE, BRIAN T. GRIMBERG
-
Patent number: 10375909Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.Type: GrantFiled: August 27, 2018Date of Patent: August 13, 2019Assignee: HEMEX HEALTH, INC.Inventors: Peter Galen, Umut Gurkan, Arwa Fraiwan, Muhammad Noman Hasan, Daniel E. Grupp, Joshua King Hoyt, James Thorne, Brian T. Grimberg
-
Patent number: 10349589Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.Type: GrantFiled: September 8, 2017Date of Patent: July 16, 2019Assignee: HEMEX HEALTH, INC.Inventors: Peter Galen, Umut Atakan Gurkan, Arwa Fraiwan, Muhammad Noman Hasan, Daniel E. Grupp, Joshua King Hoyt, James Thorne, Brian T. Grimberg
-
Publication number: 20190064113Abstract: A diagnostic device is described herein that can be used to perform magneto-optical detection and discernment of crystals within a biofluid sample. A magnetic field can be applied by the diagnostic device in a direction relative to light traveling through the sample. The presence of a crystal can be determined based on the magneto-optical properties of the sample. The detected crystal can be one of two similar crystal types that may be in the biofluid sample. The two similar crystal types can exhibit different magneto-optical properties under a magnetic field in a different direction. Accordingly, the type of crystal can be discerned by applying the magnetic field in the different direction as light travels through the sample. Discernment of the type of crystal can lead to diagnosis of the particular disease condition and subsequent proper treatment of the disease condition.Type: ApplicationFiled: August 25, 2017Publication date: February 28, 2019Inventors: Tanvir Baig, Robert Brown, Robert Deissler, Brian T. Grimberg, Abdullah Amin
-
Publication number: 20190053454Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.Type: ApplicationFiled: August 27, 2018Publication date: February 21, 2019Inventors: PETER GALEN, UMUT GURKAN, ARWA FRAIWAN, MUHAMMAD NOMAN HASAN, DANIEL E. GRUPP, JOSHUA KING HOYT, JAMES THORNE, BRIAN T. GRIMBERG
-
Publication number: 20180067101Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as a magneto-optical system that measures a light transmission differential through the patient sample in varying magnetic fields. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disease, infection and/or condition of the patient.Type: ApplicationFiled: May 18, 2017Publication date: March 8, 2018Inventors: PETER GALEN, David John Sayler, Joshua King Hoyt, Daniel E. Grupp, Brian T. Grimberg, Umat Atakan Gurkan
-
Publication number: 20180064384Abstract: A point-of-care diagnostic system that includes a cartridge and a reader. The cartridge can contain a patient sample, such as a blood sample. The cartridge is inserted into the reader and the patient sample is analyzed. The reader contains various analysis systems, such as an electrophoresis detection system that uses electrophoresis testing to identify and quantify various components of the blood sample. The reader can process data from the various patient sample analysis to provide interpretative results indicative of a disorder, condition, disease and/or infection of the patient.Type: ApplicationFiled: September 8, 2017Publication date: March 8, 2018Inventors: PETER GALEN, UMUT ATAKAN GURKAN, ARWA FRAIWAN, MUHAMMAD NOMAN HASAN, DANIEL E. GRUPP, JOSHUA KING HOYT, JAMES THORNE, BRIAN T. GRIMBERG
-
Patent number: 9778245Abstract: A diagnostic device is provided that comprises a light source for transmitting a light beam through a blood sample to a light detector, and a permanent magnet, wherein one of the permanent magnet and blood sample is automatically movable relative to the other between a “HIGH” magnetic state position and a “LOW” magnetic state position, such that a substantially high magnetic field is applied to the blood sample causing any hemozoin in the blood sample to tend toward perpendicular orientation to the substantially magnetic field and the suppression, or enhancement of light based on its polarization, and a zero-to-near-zero magnetic field is applied to the blood sample causing the randomization of any hemozoin in the blood sample and a baseline amount of light to pass through the blood sample in the “LOW” magnetic state position.Type: GrantFiled: February 6, 2017Date of Patent: October 3, 2017Assignee: Case Western Reserve UniversityInventors: Brian T. Grimberg, Robert Deissler, William Condit, Robert Brown, Jason Jones, Richard Bihary