Patents by Inventor Brian T Holmes

Brian T Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of difunctional oxyethylene-based compounds
    Patent number: 7923584
    Abstract: A method of reacting a toluenesulfonyl-terminated polyoxyethylene compound having the formula CH3—C6H4—SO2—(O—CH2—CH2)n—O—R1 with an ammonium salt having the formula NR24X to form a compound having the formula X—CH2—CH2—(O—CH2—CH2)n-1—R3. The value n is a positive integer. X is a halogen, cyanide, cyanate, thiocyanate, or azide. R1 is a terminating group. Each R2 is hydrogen or an alkyl group. —R3 is —O—R1 or —X.
    Type: Grant
    Filed: January 23, 2009
    Date of Patent: April 12, 2011
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Brian T Holmes, Arthur W Snow
  • SYNTHESIS OF DIFUNCTIONAL OXYETHYLENE-BASED COMPOUNDS
    Publication number: 20090187037
    Abstract: A method of reacting a toluenesulfonyl-terminated polyoxyethylene compound having the formula CH3—C6H4—SO2—(O—CH2—CH2)n—O—R1 with an ammonium salt having the formula NR24X to form a compound having the formula X—CH2—CH2—(O—CH2—CH2)n-1—R3. The value n is a positive integer. X is a halogen, cyanide, cyanate, thiocyanate, or azide. R1 is a terminating group. Each R2 is hydrogen or an alkyl group. —R3 is —O—R1 or —X.
    Type: Application
    Filed: January 23, 2009
    Publication date: July 23, 2009
    Inventors: Brian T. Holmes, Arthur W. Snow
  • Thioacetate deprotection
    Patent number: 7173156
    Abstract: A method of thioacetate deprotection by providing a compound of the formula R1—S—CO—R2, and reacting the compound with a quaternary ammonium cyanide salt in the presence of a protic solvent in an inert atmosphere to convert the compound to a product of the formula R1—SH. R1 is an organic group in which the bonding to sulfur is through a saturated carbon, and R2 is an aliphatic group.
    Type: Grant
    Filed: April 10, 2006
    Date of Patent: February 6, 2007
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Brian T Holmes, Arthur W Snow