Patents by Inventor Brigitte Angres

Brigitte Angres has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190367869
    Abstract: A 3D culture system based on chemically defined hydrogel scaffolds for the cultivation and expansion of pancreas-type organoids from isolated pancreatic cells in vitro.
    Type: Application
    Filed: May 30, 2019
    Publication date: December 5, 2019
    Inventors: Brigitte ANGRES, Nadine RISCHERT, Helmut WURST
  • Patent number: 8968543
    Abstract: The present invention provides an apparatus and a method to assemble organotypical tissues which can then be perfused and investigated under preferably physiological conditions.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: March 3, 2015
    Assignee: NMI Naturwissenschaftliches und Medizinisches Institut an der Universitaet Tuebingen
    Inventors: Martin Stelzle, Brigitte Angres, Massimo Kubon, Julia Schuette, Britta Hagmeyer, Felix Holzner
  • Patent number: 8268152
    Abstract: A microfluidic system (12) for assembling and subsequently investigating complex cell arrangements has a three-dimensional microstructure (11) in which the cell culture is assembled, cultivated and investigated. At least two microchannel segments (16, 17) through which the microstructure (11) can be perfused from outside with a medium (21, 22) run in the microstructure (11), whereby the microchannel segments (16, 17) run at least in sections approximately parallel or equidistant to one another. The two microchannel segments (16, 17) are separated from one another by a wall structure (25) in which at least one aperture (26) connecting the two microchannel segments (16, 17) is provided. An electrode arrangement (27) is provided in or on the microstructure (11) in order to generate an inhomogeneous electric field (28) in the region of the at least one aperture (26).
    Type: Grant
    Filed: October 1, 2010
    Date of Patent: September 18, 2012
    Assignee: NMI Naturwissenschaftliches und Medizinisches Institut an der Universitaet Tuebingen
    Inventors: Martin Stelzle, Brigitte Angres, Massimo Kubon, Julia Schuette, Britta Hagmeyer, Felix Holzner
  • Publication number: 20120199487
    Abstract: The present invention provides an apparatus and a method to assemble organotypical tissues which can then be perfused and investigated under preferably physiological conditions.
    Type: Application
    Filed: March 22, 2012
    Publication date: August 9, 2012
    Applicant: NMI Naturwissenschaftliches und Medizinisches Institute an der Universitaet Tuebingen
    Inventors: Martin STELZLE, Brigitte Angres, Massimo Kubon, Julia Schuette, Britta Hagmeyer, Felix Holzner
  • Publication number: 20110079513
    Abstract: A microfluidic system (12) for assembling and subsequently investigating complex cell arrangements has a three-dimensional microstructure (11) in which the cell culture is assembled, cultivated and investigated. At least two microchannel segments (16, 17) through which the microstructure (11) can be perfused from outside with a medium (21, 22) run in the microstructure (11), whereby the microchannel segments (16, 17) run at least in sections approximately parallel or equidistant to one another. The two microchannel segments (16, 17) are separated from one another by a wall structure (25) in which at least one aperture (26) connecting the two microchannel segments (16, 17) is provided. An electrode arrangement (27) is provided in or on the microstructure (11) in order to generate an inhomogeneous electric field (28) in the region of the at least one aperture (26).
    Type: Application
    Filed: October 1, 2010
    Publication date: April 7, 2011
    Inventors: Martin Stelzle, Brigitte Angres, Massimo Kubon, Julia Schuette, Britta Hagmeyer, Felix Holzner
  • Patent number: 7455816
    Abstract: The invention relates to a method for coating a support plate for carrying out functional tests on biological cells, to a support plate for carrying out functional tests on biological cells and to the use of corresponding support plates for carrying out functional tests on biological cells.
    Type: Grant
    Filed: February 9, 2007
    Date of Patent: November 25, 2008
    Assignee: NMI Naturwissenschaftliches und Medizinisches Institut an der Universitaet Tuebingen
    Inventors: Heiko Steuer, Markus Templin, Britta Kanzok, Cornelia Kuschel, Brigitte Angres
  • Publication number: 20070218546
    Abstract: The invention relates to a method for coating a support plate for carrying out functional tests on biological cells, to a support plate for carrying out functional tests on biological cells and to the use of corresponding support plates for carrying out functional tests on biological cells.
    Type: Application
    Filed: February 9, 2007
    Publication date: September 20, 2007
    Applicant: NMI Naturwissenschaftliches und Medizinisches Institut an der Universitat Tubingen
    Inventors: Heiko Steuer, Markus Templin, Britta Kanzok, Cornelia Kuschel, Brigitte Angres