Patents by Inventor Brijesh Kumar Singh

Brijesh Kumar Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240156913
    Abstract: Methods of treating and preventing metabolic disease through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods.
    Type: Application
    Filed: October 6, 2023
    Publication date: May 16, 2024
    Applicants: Singapore Health Services PTE LTD., National University of Singapore
    Inventors: Stuart Alexander Cook, Sebastian Schaefer, Brijesh Kumar Singh, Anissa Widjaja
  • Publication number: 20230399393
    Abstract: The present disclosure relates to the diagnosis, treatment and prophylaxis of age-related diseases, and increasing healthspan. Provided are methods of treating or preventing an age-related disease/condition, and in particular of treating or preventing frailty, comprising administering a therapeutically or prophylactically effective amount of an agent capable of inhibiting interleukin 11 (IL-11)-mediated signalling to a subject. Also provided are agents capable of inhibiting interleukin 11 (IL-11)-mediated signalling for use in such a method. Further provided is the use of agents capable of inhibiting interleukin 11 (IL-11)-mediated signalling in the manufacture of a medicament for use in such a method.
    Type: Application
    Filed: October 29, 2021
    Publication date: December 14, 2023
    Applicants: National University of Singapore, Singapore Health Services PTE LTD.
    Inventors: Benjamin Corden, Anissa Widjaja, Sebastian Schaeffer, Stuart Cook, Brijesh Kumar Singh
  • Patent number: 11813311
    Abstract: Methods of treating and preventing metabolic disease through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: November 14, 2023
    Assignees: Singapore Health Services PTE LTD., National University of Singapore
    Inventors: Stuart Alexander Cook, Sebastian Schaefer, Brijesh Kumar Singh, Anissa Widjaja
  • Publication number: 20220275400
    Abstract: The present invention relates to high throughput in vitro genetic manipulation. In particular, it relates to scalable CRISPR gene insertions in mammalian cells.
    Type: Application
    Filed: August 31, 2020
    Publication date: September 1, 2022
    Inventors: Alejandro Chavez, Brijesh Kumar Singh
  • Publication number: 20210177940
    Abstract: Methods of treating and preventing metabolic disease through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods.
    Type: Application
    Filed: May 1, 2020
    Publication date: June 17, 2021
    Applicants: Singapore Health Services PTE LTD., National University of Singapore
    Inventors: Stuart Alexander Cook, Sebastian Schaefer, Brijesh Kumar Singh, Anissa Widjaja