Abstract: The present invention provides a continuous solvent free and additive free process for the synthesis of Metformin Hydrochloride in a screw reactor. >90% conversion of the solid substrates without solvent is obtained in a screw reactor to produce Metformin Hydrochloride with at least 90% selectivity.

Abstract: A method and a system for identifying optimal communication mode and health management modules for patient engagement includes receiving patient data from one or more data sources. Upon receiving the patient data, the patient engagement system determines a disease value for each of one or more diseases prevalent in a region, treatment value for each of the one or more diseases and technology value for each of the one or more technologies prevalent in the region. Based on the disease value and the treatment value, the patient engagement system determines one or more patient engagement modules and based on the technology value an optimal communication mode is determined. The one or more modules determined are provided to the patient through the optimal communication mode.

Abstract: The present invention discloses triazine compounds of Formula II and a process to synthesize these compounds. Particularly, the invention provides one pot method to synthesize triazines nucleus, wherein the method comprises amination followed by using Leuckart reaction conditions of pyrrole/indole-2-carboxylates of Formula I to obtain corresponding triazine compounds of Formula II.

Abstract: The present invention discloses triazine compounds of Formula II and a process to synthesize these compounds. Particularly, the invention provides one pot method to synthesize triazines nucleus, wherein the method comprises amination followed by using Leuckart reaction conditions of pyrrole/indole-2-carboxylates of Formula I to obtain corresponding triazine compounds of Formula II.