Patents by Inventor Britta Siekmann
Britta Siekmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230124105Abstract: The present invention relates to pharmaceutical compositions having improved stability.Type: ApplicationFiled: July 12, 2022Publication date: April 20, 2023Applicant: Ferring B.V.Inventors: Anders Nilsson, Mattias Malm, Kazimierz Wisniewski, Britta Siekmann
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Publication number: 20170106043Abstract: The present invention relates to pharmaceutical compositions having improved stability.Type: ApplicationFiled: December 28, 2016Publication date: April 20, 2017Inventors: Anders Nilsson, Mattias Malm, Kazimierz Wisniewski, Britta Siekmann
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Publication number: 20170106044Abstract: The present invention relates to pharmaceutical compositions having improved stability.Type: ApplicationFiled: December 28, 2016Publication date: April 20, 2017Inventors: Anders Nilsson, Mattias Malm, Kazimierz Wisniewski, Britta Siekmann
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Patent number: 9566311Abstract: The present invention relates to pharmaceutical compositions having improved stability.Type: GrantFiled: September 29, 2011Date of Patent: February 14, 2017Assignee: Ferring B.V.Inventors: Britta Siekmann, Mattias Malm, Anders Nilsson, Kazimierz Wisniewski
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Patent number: 9522377Abstract: The present invention provides a method for forming a dispersion comprising non-lamellar amphiphile particles having improved phase behavior, particle size distribution and/or storage stability, said method comprising forming a dispersion of lamellar and optionally non-lamellar particles comprising at least one structuring agent in a polar solvent, heating said particles to an elevated temperature, followed by cooling, wherein said heating is to a temperature and for a period sufficient to provide, after cooling, a measurable improvement in phase behavior, particle size distribution and/or storage stability.Type: GrantFiled: August 4, 2004Date of Patent: December 20, 2016Assignee: CAMURUS ABInventors: Gert Wörle, Fredrik Tiberg, Markus Johnsson, Heike Bunjes, Britta Siekmann, Justas Barauskas
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Publication number: 20130210746Abstract: The present invention relates to pharmaceutical compositions having improved stability.Type: ApplicationFiled: September 29, 2011Publication date: August 15, 2013Applicant: FERRING B.V.Inventors: Britta Siekmann, Mattias Malm, Anders Nilsson, Kazimierz Wisniewski
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Publication number: 20100266683Abstract: The present invention claims and discloses a pharmaceutical composition suitable for oral administration, in form of an emulsion pre-concentrate, comprising (i) a compound of the formula (I) (ii) one or more surfactants; (iii) optionally an oil or semi-solid fat; said composition forming an in-situ oil-in-water emulsion upon contact with aqueous media such as gastrointestinal fluids. The composition may optionally also comprise one or more short-chain alcohols. The pharmaceutical composition is useful in the treatment of pain and inflammation.Type: ApplicationFiled: April 28, 2010Publication date: October 21, 2010Applicant: NICOX S.A.Inventors: Christina HOLMBERG, Britta Siekmann
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Patent number: 7736666Abstract: The present invention claims and discloses a pharmaceutical composition suitable for oral administration, in form of an emulsion pre-concentrate, comprising (i) a compound of formula (I); (ii) one or more surfactants; (iii) optionally an oil or semi-solid fat; said composition forming an in-situ oil-in-water emulsion upon contact with aqueous media such as gastrointestinal fluids. The composition may optionally also comprise one or more short-chain alcohols. The pharmaceutical composition is useful in the treatment of pain and inflammation.Type: GrantFiled: March 6, 2001Date of Patent: June 15, 2010Assignee: Nicox S.A.Inventors: Christina Holmberg, Britta Siekmann
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Publication number: 20070134336Abstract: The present invention provides a method for forming a dispersion comprising non-lamellar amphiphile particles having improved phase behaviour, particle size distribution and/or storage stability, said method comprising forming a dispersion of lamellar and optionally non-lamellar particles comprising at least one structuring agent in a polar solvent, heating said particles to an elevated temperature, followed by cooling, wherein said heating is to a temperature and for a period sufficient to provide, after cooling, a measurable improvement in phase behaviour, particle size distribution and/or storage stability.Type: ApplicationFiled: August 4, 2004Publication date: June 14, 2007Applicant: CAMURUS ABInventors: Gert Worle, Frederik Tiberg, Markus Johnsson, Heike Bunjes, Britta Siekmann, Justas Barauskas
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Publication number: 20040096494Abstract: A new pharmaceutical composition in the form of lipoglobules which comprises (a) one or more NO-releasing NSAID(s); (b) one or more surfactant(s); and (c) an aqueous phase, as well as a process for the preparation of such composition and the use of such composition in the treatment of pain and inflammation.Type: ApplicationFiled: September 9, 2003Publication date: May 20, 2004Inventors: Britta Siekmann, Barbo Thoring
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Publication number: 20030161846Abstract: The present invention claims and discloses a pharmaceutical composition suitable for oral administration, in form of an emulsion pre-concentrate, comprisingType: ApplicationFiled: September 5, 2002Publication date: August 28, 2003Inventors: Christina Holmberg, Britta Siekmann
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Publication number: 20030077303Abstract: The present invention claims and discloses a pharmaceutical composition suitable for oral administration, in form of an emulsion pre-concentrate, comprising (i) a compound of formula (I); (ii) one or more surfactants; (iii) optionally an oil or semi-solid fat; said composition forming an in-situ oil-in-water emulsion upon contact with aqueous media such as gastrointestinal fluids. The composition may optionally also comprise one or more short-chain alcohols. The pharmaceutical composition is useful in the treatment of pain and inflammation.Type: ApplicationFiled: September 5, 2002Publication date: April 24, 2003Inventors: Christina Holmberg, Britta Siekmann
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Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
Patent number: 6207178Abstract: The present invention is in the area of administration forms and delivery systems for drugs, vaccines and other biologically active agents. More specifically the invention is related to the preparation of suspensions of colloidal solid lipid particles (SLPs) of predominantly anisometrical shape with the lipid matrix being in a stable polymorphic modification and of suspensions of micron and submicron particles of bioactive agents (PBAs); as well as to the use of such suspensions or the lyophilizates thereof as delivery systems primarily for the parenteral administration of preferably poorly water-soluble bioactive substances, particularly drugs, and to their use in cosmetic, food and agricultural products. SLPs and PBAs are prepared by the following emulsification process: (1) A solid lipid or bioactive agent or a mixture of solid lipids or bioactive agents is melted.Type: GrantFiled: December 3, 1998Date of Patent: March 27, 2001Assignee: Kabi Pharmacia ABInventors: Kirsten Westesen, Britta Siekmann -
Patent number: 6197349Abstract: Particles comprising (a) a supercooled melt of a poorly water-soluble substance and (b) a stabilizing agent, which have a mean particle size of between 30 and 500 nm, and disperse compositions containing them, as administration forms and delivery systems for drugs, vaccines and other biologically active agents such as herbicides, pesticides, insecticides, fungicides, fertilizers, vitamins, nutrition additives and cosmetics.Type: GrantFiled: November 6, 1997Date of Patent: March 6, 2001Assignee: Knoll AktiengesellschaftInventors: Kirsten Westesen, Britta Siekmann
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Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
Patent number: 5885486Abstract: The present invention is in the area of administration forms and delivery systems for drugs, vaccines and other biologically active agents. More specifically the invention is related to the preparation of suspensions of colloidal solid lipid particles (SLPs) of predominantly anisometrical shape with the lipid matrix being in a stable polymorphic modification and of suspensions of micron and submicron particles of bioactive agents (PBAs); as well as to the use of such suspensions or the lyophilizates thereof as delivery systems primarily for the parenteral administration of preferably poorly water-soluble bioactive substances, particularly drugs, and to their use in cosmetic, food and agricultural products.SLPs and PBAs are prepared by the following emulsification process:(1) A solid lipid or bioactive agent or a mixture of solid lipids or bioactive agents is melted.Type: GrantFiled: December 2, 1996Date of Patent: March 23, 1999Assignee: Pharmaciaand Upjohn ABInventors: Kirsten Westesen, Britta Siekmann -
Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof
Patent number: 5785976Abstract: The present invention is in the area of administration forms and delivery systems for drugs, vaccines and other biologically active agents. More specifically the invention is related to the preparation of suspensions of colloidal solid lipid particles (SLPs) of predominantly anisometrical shape with the lipid matrix being in a stable polymorphic modification and of suspensions of micron and submicron particles of bioactive agents (PBAs); as well as to the use of such suspensions or the lyophilizates thereof as delivery systems primarily for the parenteral administration of preferably poorly water-soluble bioactive substances, particularly drugs, and to their use in cosmetic, food and agricultural products.SLPs and PBAs are prepared by the following emulsification process:(1) A solid lipid or bioactive agent or a mixture of solid lipids or bioactive agents is melted.Type: GrantFiled: April 12, 1994Date of Patent: July 28, 1998Assignee: Pharmacia & UpJohn ABInventors: Kirsten Westesen, Britta Siekmann