Patents by Inventor Britta Villbrandt

Britta Villbrandt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polymerase chimeras
    Patent number: 7244602
    Abstract: The invention concerns polymerase chimeras which are composed of amino acid fragments representing domains and which combine properties of naturally occurring polymerases that are advantageous with regard to a particular application. It has surprisingly turned out that the domains from the various enzymes are active in the chimeras and exhibit cooperative behavior. In addition the present invention concerns a process for the production of the chimeras according to the invention and the use of these chimeras for the synthesis of nucleic acids e.g. during a polymerase chain reaction. Moreover the present invention concerns a kit which contains the polymerase chimeras according to the invention.
    Type: Grant
    Filed: June 6, 2003
    Date of Patent: July 17, 2007
    Assignee: Roche Diagnostics GmbH
    Inventors: Bruno Frey, Britta Villbrandt, Dietmar Schomburg, Harald Sobek, Waltraud Ankenbauer
  • Polymerase chimeras
    Publication number: 20040058362
    Abstract: The invention concerns polymerase chimeras which are composed of amino acid fragments representing domains and which combine properties of naturally occurring polymerases that are advantageous with regard to a particular application. It has surprisingly turned out that the domains from the various enzymes are active in the chimeras and exhibit cooperative behaviour. In addition the present invention concerns a process for the production of the chimeras according to the invention and the use of these chimeras for the synthesis of nucleic acids e.g. during a polymerase chain reaction. Moreover the present invention concerns a kit which contains the polymerase chimeras according to the invention.
    Type: Application
    Filed: June 6, 2003
    Publication date: March 25, 2004
    Applicant: Roche Diagnostics GmbH
    Inventors: Bruno Frey, Britta Villbrandt, Dietmar Schomburg, Harald Sobek, Waltraud Ankenbauer
  • Polymerase chimeras
    Patent number: 6607883
    Abstract: The invention concerns polymerase chimeras which are composed of amino acid fragments representing domains and which combine properties of naturally occurring polymerases that are advantageous with regard to a particular application. It has surprisingly turned out that the domains from the various enzymes are active in the chimeras and exhibit cooperative behavior. In addition the present invention concerns a process for the production of the chimeras according to the invention and the use of these chimeras for the synthesis of nucleic acids e.g. during a polymerase chain reaction. Moreover the present invention concerns a kit which contains the polymerase chimeras according to the invention.
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: August 19, 2003
    Assignee: Roche Diagnostics GmbH
    Inventors: Bruno Frey, Britta Villbrandt, Dietmar Schomburg, Harald Sobek, Waltraud Ankenbauer