Patents by Inventor Brooke PRINZING

Brooke PRINZING has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC MYD88 RECEPTORS
    Publication number: 20230340040
    Abstract: The present disclosure provides chimeric MyD88 receptors. Also provided are polynucleotides encoding the chimeric MyD88 receptors, vectors comprising the polynucleotides encoding the chimeric MyD88 receptors, and cell compositions comprising the chimeric MyD88 receptors, polynucleotides and/or vectors. Pharmaceutical compositions comprising the polypeptides, polynucleotides, vectors, or cells of the present disclosure, and their uses in treating a disease in a subject are also provided.
    Type: Application
    Filed: April 14, 2021
    Publication date: October 26, 2023
    Applicant: St. Jude Children's Research Hospital, Inc.
    Inventors: Stephen GOTTSCHALK, Brooke PRINZING
  • CHIMERIC ANTIGEN RECEPTORS WITH MYD88 AND CD40 COSTIMULATORY DOMAINS
    Publication number: 20210252058
    Abstract: The application relates to a chimeric antigen receptor that targets Eph receptors and allows activation of co-stimulatory pathways. The application also relates to polynucleotides that encode the chimeric antigen receptor, vectors, and host cells comprising the chimeric antigen receptor. The application also relates to methods for preparing host cells comprising a chimeric antigen receptor in order to improve the in vivo effector function of the chimeric antigen receptor host cells.
    Type: Application
    Filed: May 17, 2019
    Publication date: August 19, 2021
    Applicants: ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC., BAYLOR COLLEGE OF MEDICINE
    Inventors: Stephen GOTTSCHALK, Brooke PRINZING, Giedre KRENCIUTE