Abstract: An opaque or transparent panel assembly for a vehicle having a weather and noise seal for an opening in the vehicle. The assembly includes a first panel having a peripheral edge wherein at least portions of the peripheral edge are encased or captured by a molded PVC or reaction injection molded (RIM) urethane gasket. A portion of the gasket is located so as to lie adjacent the opening to receive the seal. A seal carrier is provided and captured within the portion of the gasket adjacent the opening so that a first portion of the carrier is secured within the gasket. A second portion of the carrier includes a flange which extends into the opening by a predetermined distance. A seal is disposed along the flange which is adapted to engage the panel closing the vehicle opening to form the secondary seal. The seal may be a bulb or bubble seal mounted on the flange. Alternatively, the panel closing the vehicle opening may be a door or window. The first panel may be a windscreen, rear light or side window.