Patents by Inventor Bruce C. Nisula

Bruce C. Nisula has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Natural human chorionic gonadotropin .beta.-core molecule
    Patent number: 5674983
    Abstract: The present invention relates to the purification of the human chorionic gonadotropin .beta.-core molecule which can then be used as the antigen in the preparation of antibodies to the .beta.-core molecule. The combination of the purified .beta.-core molecule and the antibodies can be used in an immunoassay kit to measure .beta.-core molecules in the presence of structurally similar molecules, i.e., hCG, LH, hCG.beta.-subunit and LH.beta.-subunit. Measurement of the .beta.-core molecule is particularly useful in testing for pregnancy and many malignancies.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: October 7, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Diana L. Blithe, Robert E. Wehmann, Bruce C. Nisula
  • Purification of human chorionic gonadotropin .beta.-core molecule and preparation of antibodies with specificity for same
    Patent number: 5445968
    Abstract: The present invention relates to the purification of the human chorionic gonadotropin .beta.-core molecule which can then be used as the antigen in the preparation of antibodies to the .beta.-core molecule. The combination of the purified .beta.-core molecule and the antibodies can be used in an immunoassay kit to measure .beta.-core molecules in the presence of structurally similar molecules, i.e., hCG, LH, hCG.beta.-subunit and LH.beta.-subunit. Measurement of the .beta.-core molecule is particularly useful in testing for pregnancy and many malignancies.
    Type: Grant
    Filed: November 12, 1991
    Date of Patent: August 29, 1995
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Diana Blithe, Robert E. Wehmann, Bruce C. Nisula