Patents by Inventor Bruce E. DeSimas
Bruce E. DeSimas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9482652Abstract: Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.Type: GrantFiled: September 10, 2013Date of Patent: November 1, 2016Assignee: Applied Biosystems, LLCInventors: Bruce E. DeSimas, Leslie A. Dow
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Publication number: 20150080256Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.Type: ApplicationFiled: October 15, 2014Publication date: March 19, 2015Inventors: Michael R. GAMBINI, Jeff A. Levi, John C. Voyta, John G. Atwood, Bruce E. DeSimas, II, Edward J. Lakatos, Israel Metal, George Sabak, Yongdong Wang
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Patent number: 8865473Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. A detecting apparatus may be configured so that light from luminescent samples pass through a collimator, a first lens, a filter, and a camera lens, whereupon an image is created by the optics on the charge-coupled device (CCD) camera. The detecting apparatus may further include central processing control of all operations, multiple wavelength filter wheel, and/or a robot for handling of samples and reagents.Type: GrantFiled: August 13, 2012Date of Patent: October 21, 2014Assignee: Applied Biosystems, LLCInventors: Michael Gambini, Jeff Levi, John Voyta, Bruce E. DeSimas, II, Edward Lakatos, Israel Metal, George Sabak, Yongdong Wang, Susan A. Atwood-Stone
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Publication number: 20140122006Abstract: Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.Type: ApplicationFiled: September 10, 2013Publication date: May 1, 2014Applicant: APPLIED BIOSYSTEMS, LLCInventors: Bruce E. DeSimas, Leslie A. Dow
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Patent number: 8452562Abstract: Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.Type: GrantFiled: January 27, 2012Date of Patent: May 28, 2013Assignee: Applied Biosystems, LLCInventors: Bruce E. DeSimas, Leslie A. Dow
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Publication number: 20120309103Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.Type: ApplicationFiled: August 13, 2012Publication date: December 6, 2012Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Michael Gambini, John C. Voyta, John Atwood, Susan A. Atwood-Stone, Bruce E. DeSimas, II, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
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Publication number: 20120197571Abstract: Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.Type: ApplicationFiled: January 27, 2012Publication date: August 2, 2012Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Bruce E. DeSimas, Leslie A. Dow
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Publication number: 20110231758Abstract: The workflow application integrates with a research software application associated with a laboratory instrument to provide a user with step-by-step instructions on how to follow the workflow steps of a laboratory experiment. The instructions are dynamically tailored, according to the nature of the workflow, the samples being experimented upon and/or the operating states of the instrument and/or the research software application. The workflow application significantly reduces the learning curve to operate sophisticated laboratory instruments. In a genetic testing instrument the workflow application can prescribe the need for control samples and can optimize the layout of samples within the instrument's sample receiving plate or fixture.Type: ApplicationFiled: March 23, 2011Publication date: September 22, 2011Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Bruce E. DeSIMAS, Leslie A. Dow
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Publication number: 20100248387Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.Type: ApplicationFiled: March 2, 2010Publication date: September 30, 2010Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Michael R. Gambini, John C. Voyta, John Atwood, Susan A. Atwood-Stone, Bruce E. DeSimas, II, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
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Publication number: 20100082279Abstract: Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.Type: ApplicationFiled: December 7, 2009Publication date: April 1, 2010Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Bruce E. DeSimas, Leslie A. Dow
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Patent number: 7670848Abstract: In a luminescence detecting apparatus and method for analyzing luminescent samples, luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, an infrared filter, and a camera lens, whereupon a focused image is created by the optics on the camera. The use of an infrared filter suppresses stray IR radiation resulting from plate phosphorescence (which can result in abnormally high backgrounds and/or alteration of the image received by the camera).Type: GrantFiled: October 18, 2005Date of Patent: March 2, 2010Assignee: Applied Biosystems, LLCInventors: Michael R. Gambini, John C. Voyta, John Atwood, Susan A. Atwood-Stone, legal representative, Bruce E. DeSimas, II, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
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Patent number: 7630849Abstract: Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.Type: GrantFiled: August 31, 2006Date of Patent: December 8, 2009Assignee: Applied Biosystems, LLCInventors: Bruce E. DeSimas, Leslie A. Dow
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Publication number: 20090226916Abstract: The present invention provides a system and methods for deconvoluting mixed DNA samples. Applications developed according to the invention may be used for resolving two or more person mixtures into easy to interpret contributor profiles and to perform automated statistical calculations. An automated analysis approach for mixed samples integrating hardware and software functionalities providing enhanced user convenience and functionality is also provided.Type: ApplicationFiled: February 2, 2009Publication date: September 10, 2009Applicant: Life Technologies CorporationInventors: Bruce E. DeSimas, Ravi Gupta, Lisa M. Calandro
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Publication number: 20030092194Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.Type: ApplicationFiled: December 20, 2002Publication date: May 15, 2003Inventors: Michael R. Gambini, John C. Voyta, John Atwood, Bruce E. DeSimas, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
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Patent number: 6518068Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.Type: GrantFiled: July 21, 2000Date of Patent: February 11, 2003Assignee: Tropix, Inc.Inventors: Michael R. Gambini, John C. Voyta, John Atwood, Bruce E. DeSimas, II, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang