Patents by Inventor Bruce E. DeSimas

Bruce E. DeSimas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9482652
    Abstract: Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: November 1, 2016
    Assignee: Applied Biosystems, LLC
    Inventors: Bruce E. DeSimas, Leslie A. Dow
  • Publication number: 20150080256
    Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.
    Type: Application
    Filed: October 15, 2014
    Publication date: March 19, 2015
    Inventors: Michael R. GAMBINI, Jeff A. Levi, John C. Voyta, John G. Atwood, Bruce E. DeSimas, II, Edward J. Lakatos, Israel Metal, George Sabak, Yongdong Wang
  • Patent number: 8865473
    Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. A detecting apparatus may be configured so that light from luminescent samples pass through a collimator, a first lens, a filter, and a camera lens, whereupon an image is created by the optics on the charge-coupled device (CCD) camera. The detecting apparatus may further include central processing control of all operations, multiple wavelength filter wheel, and/or a robot for handling of samples and reagents.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: October 21, 2014
    Assignee: Applied Biosystems, LLC
    Inventors: Michael Gambini, Jeff Levi, John Voyta, Bruce E. DeSimas, II, Edward Lakatos, Israel Metal, George Sabak, Yongdong Wang, Susan A. Atwood-Stone
  • Publication number: 20140122006
    Abstract: Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.
    Type: Application
    Filed: September 10, 2013
    Publication date: May 1, 2014
    Applicant: APPLIED BIOSYSTEMS, LLC
    Inventors: Bruce E. DeSimas, Leslie A. Dow
  • Patent number: 8452562
    Abstract: Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: May 28, 2013
    Assignee: Applied Biosystems, LLC
    Inventors: Bruce E. DeSimas, Leslie A. Dow
  • Publication number: 20120309103
    Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.
    Type: Application
    Filed: August 13, 2012
    Publication date: December 6, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Michael Gambini, John C. Voyta, John Atwood, Susan A. Atwood-Stone, Bruce E. DeSimas, II, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
  • Publication number: 20120197571
    Abstract: Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.
    Type: Application
    Filed: January 27, 2012
    Publication date: August 2, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Bruce E. DeSimas, Leslie A. Dow
  • Publication number: 20110231758
    Abstract: The workflow application integrates with a research software application associated with a laboratory instrument to provide a user with step-by-step instructions on how to follow the workflow steps of a laboratory experiment. The instructions are dynamically tailored, according to the nature of the workflow, the samples being experimented upon and/or the operating states of the instrument and/or the research software application. The workflow application significantly reduces the learning curve to operate sophisticated laboratory instruments. In a genetic testing instrument the workflow application can prescribe the need for control samples and can optimize the layout of samples within the instrument's sample receiving plate or fixture.
    Type: Application
    Filed: March 23, 2011
    Publication date: September 22, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Bruce E. DeSIMAS, Leslie A. Dow
  • Publication number: 20100248387
    Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.
    Type: Application
    Filed: March 2, 2010
    Publication date: September 30, 2010
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Michael R. Gambini, John C. Voyta, John Atwood, Susan A. Atwood-Stone, Bruce E. DeSimas, II, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
  • Publication number: 20100082279
    Abstract: Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.
    Type: Application
    Filed: December 7, 2009
    Publication date: April 1, 2010
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Bruce E. DeSimas, Leslie A. Dow
  • Patent number: 7670848
    Abstract: In a luminescence detecting apparatus and method for analyzing luminescent samples, luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, an infrared filter, and a camera lens, whereupon a focused image is created by the optics on the camera. The use of an infrared filter suppresses stray IR radiation resulting from plate phosphorescence (which can result in abnormally high backgrounds and/or alteration of the image received by the camera).
    Type: Grant
    Filed: October 18, 2005
    Date of Patent: March 2, 2010
    Assignee: Applied Biosystems, LLC
    Inventors: Michael R. Gambini, John C. Voyta, John Atwood, Susan A. Atwood-Stone, legal representative, Bruce E. DeSimas, II, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
  • Patent number: 7630849
    Abstract: Method and system providing an automated workflow for installing and/or calibrating laboratory equipment. The workflow empowers an end user to perform installation and calibration thereby reducing the costs associated with such activities. The automated workflow taught herein, can greatly reduce the incidence of calibration error by providing for verification of certain events during the calibration process.
    Type: Grant
    Filed: August 31, 2006
    Date of Patent: December 8, 2009
    Assignee: Applied Biosystems, LLC
    Inventors: Bruce E. DeSimas, Leslie A. Dow
  • Publication number: 20090226916
    Abstract: The present invention provides a system and methods for deconvoluting mixed DNA samples. Applications developed according to the invention may be used for resolving two or more person mixtures into easy to interpret contributor profiles and to perform automated statistical calculations. An automated analysis approach for mixed samples integrating hardware and software functionalities providing enhanced user convenience and functionality is also provided.
    Type: Application
    Filed: February 2, 2009
    Publication date: September 10, 2009
    Applicant: Life Technologies Corporation
    Inventors: Bruce E. DeSimas, Ravi Gupta, Lisa M. Calandro
  • Publication number: 20030092194
    Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.
    Type: Application
    Filed: December 20, 2002
    Publication date: May 15, 2003
    Inventors: Michael R. Gambini, John C. Voyta, John Atwood, Bruce E. DeSimas, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang
  • Patent number: 6518068
    Abstract: A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. Luminescent samples are placed in a plurality of sample wells in a tray, and the tray is placed in a visible-light impervious chamber containing a charge coupled device camera. The samples may be injected in the wells, and the samples may be injected with buffers and reagents, by an injector. In the chamber, light from the luminescent samples pass through a collimator, a Fresnel field lens, a filter, and a camera lens, whereupon a focused image is created by the optics on the charge-coupled device (CCD) camera. The use of a Fresnel field lens, in combination with a collimator and filter, reduces crosstalk between samples below the level attainable by the prior art. Preferred embodiments of the luminescence detecting apparatus and method disclosed include central processing control of all operations, multiple wavelength filter wheel, and robot handling of samples and reagents.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: February 11, 2003
    Assignee: Tropix, Inc.
    Inventors: Michael R. Gambini, John C. Voyta, John Atwood, Bruce E. DeSimas, II, Edward Lakatos, Jeff Levi, Israel Metal, George Sabak, Yongdong Wang