Patents by Inventor Bruce E. Holbein

Bruce E. Holbein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220002250
    Abstract: Disclosed are chelating co-polymer compositions that are soluble in aqueous media and chelate essential metals, methods of preparation and uses thereof. The chelating compositions are comprised of two or more different monomers, at least one of which possesses metal binding or metal chelating activity. The chelating compositions are synthesized by reversible addition-fragmentation transfer (RAFT) polymerization with the aid of a suitable RAFT-mediating agent. Also described are chelating compositions that comprise hydroxypyridinone chelating groups. The ability of the chelating compositions to bind metals affects the activity of a living cells and organisms, which require the metals for cellular functions.
    Type: Application
    Filed: May 28, 2021
    Publication date: January 6, 2022
    Inventors: Bruce E. Holbein, M. Trisha C. Ang, Dnyaneshwar Vithoba Palaskar, Ganugapati Satyanarayana, Gireesh Mahandru, S. Vijaya Bhaskara Reddy, Sazid Ali
  • Patent number: 11059785
    Abstract: Disclosed are chelating co-polymer compositions that are soluble in aqueous media and chelate essential metals, methods of preparation and uses thereof. The chelating compositions are comprised of two or more different monomers, at least one of which possesses metal binding or metal chelating activity. The chelating compositions are synthesized by reversible addition-fragmentation transfer (RAFT) polymerization with the aid of a suitable RAFT-mediating agent. Also described are chelating compositions that comprise hydroxypyridinone chelating groups. The ability of the chelating compositions to bind metals affects the activity of a living cells and organisms, which require the metals for cellular functions.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: July 13, 2021
    Assignee: CHELATION PARTNERS INCORPORATED
    Inventors: Bruce E. Holbein, M. Trisha C. Ang, Dnyaneshwar Vithoba Palaskar, Ganugapati Satyanarayana, Gireesh Mahandru, S. Vijaya Bhaskara Reddy, Sazid Ali
  • Publication number: 20190169126
    Abstract: Disclosed are chelating co-polymer compositions that are soluble in aqueous media and chelate essential metals, methods of preparation and uses thereof. The chelating compositions are comprised of two or more different monomers, at least one of which possesses metal binding or metal chelating activity. The chelating compositions are synthesized by reversible addition-fragmentation transfer (RAFT) polymerization with the aid of a suitable RAFT-mediating agent. Also described are chelating compositions that comprise hydroxypyridinone chelating groups. The ability of the chelating compositions to bind metals affects the activity of a living cells and organisms, which require the metals for cellular functions.
    Type: Application
    Filed: August 25, 2017
    Publication date: June 6, 2019
    Inventors: Bruce E. Holbein, M. Trisha C. Ang, Dnyaneshwar Vithoba Palaskar, Ganugapati Satyanarayana, Gireesh Mahandru, S. Vijaya Bhaskara Reddy, Sazid Ali
  • Patent number: 5342449
    Abstract: The present invention relates to the decontamination of soil and the like and, in particular, soils which are contaminated with metal as a result of the activities of human beings. The invention provides a physical and a chemical means for treating soil aggregate so as to obtain a product aggregate having a relatively low metal content. The physical means is characterized by the classification of a soil aggregate into portions of differing size and metal content. The chemical means is characterized by contacting a soil aggregate with an aqueous lixiviant comprising an organic acid component to lift metal from the aggregate. The physical and chemical means may be used in a combined process for decontaminating soil aggregate.
    Type: Grant
    Filed: December 9, 1991
    Date of Patent: August 30, 1994
    Inventors: Bruce E. Holbein, Denis K. Kidby
  • Patent number: 4752398
    Abstract: A method for removing mercury and other related metals such as cadmium, zinc, copper, silver, from a liquid medium. This method comprises the step of contacting the liquid medium with an insoluble composition comprising an suitable insoluble carrier and a cysteine residue covalently fixed at the nitrogen atom thereof to the surface of the carrier.
    Type: Grant
    Filed: March 27, 1987
    Date of Patent: June 21, 1988
    Inventors: Bruce E. Holbein, David Brener, Charles W. Greer, Eric N. C. Browne
  • Patent number: 4654322
    Abstract: An insoluble composition for removing mercury from a liquid medium comprises a suitable insoluble carrier and a cysteine residue convalently fixed at the nitrogen atom thereof to the surface of the carrier.
    Type: Grant
    Filed: August 5, 1985
    Date of Patent: March 31, 1987
    Assignee: DeVoe-Holbein International, N.V.
    Inventors: Bruce E. Holbein, David Brener, Charles Greer, Eric N. C. Browne
  • Patent number: 4626416
    Abstract: The present invention relates to insoluble compositions, which are capable of removing metal (e.g. selectively) from solution (e.g. Fe.sup.3+ from a liquid nutrient medium so as to lower the Fe.sup.3+ content to less than 0.1 .mu.M); the insoluble compositions comprise: a suitable insoluble carrier and organic co-ordinating sites covalently fixed to the surface of said carrier, said co-ordinating sites being capable of chelating Fe.sup.3+, Th.sup.4+ and/or UO.sub.2.sup.2+.
    Type: Grant
    Filed: June 22, 1984
    Date of Patent: December 2, 1986
    Assignee: Devoe-Holbein International, N.V.
    Inventors: Irving W. DeVoe, Bruce E. Holbein
  • Patent number: 4585559
    Abstract: The present invention relates to insoluble compositions, which are capable of removing metal (e.g. selectively) from solution (e.g. Fe.sup.3+ from a liquid nutrient medium so as to lower the Fe.sup.3+ content to less than 0.1 .mu.M); the insoluble compositions comprise: a suitable insoluble carrier and organic co-ordinating sites covalently fixed to the surface of said carrier, said co-ordinating sites being capable of chelating Fe.sup.3+, Th.sup.4+ and/or UO.sub.2.sup.2+.
    Type: Grant
    Filed: June 28, 1984
    Date of Patent: April 29, 1986
    Assignee: DeVoe-Holbein International, N.V.
    Inventors: Irving W. DeVoe, Bruce E. Holbein
  • Patent number: 4530963
    Abstract: The present invention relates to insoluble compositions, which are capable of removing metal (e.g. selectively) from solution (e.g. Fe.sup.3+ from a liquid nutrient medium so as to lower the Fe.sup.3+ content to less than 0.1 .mu.M); the insoluble compositions comprise: a suitable insoluble carrier and organic co-ordinating sites covalently fixed to the surface of said carrier, said co-ordinating sites being capable of chelating Fe.sup.3+, Th.sup.4+ and/or UO.sub.2.sup.2+.
    Type: Grant
    Filed: February 24, 1983
    Date of Patent: July 23, 1985
    Assignee: Devoe-Holbein International, N.V.
    Inventors: Irving W. DeVoe, Bruce E. Holbein