Patents by Inventor Bruce E. Kimmel

Bruce E. Kimmel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antigen-binding polypeptides and their uses
    Patent number: 9175083
    Abstract: Novel antigen-binding polypeptides (ABP) and uses thereof are provided.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: November 3, 2015
    Assignee: AMBRX, INC.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Troy E. Wilson, Thomas P. Cujec, Feng Tian, Anna-Maria A. Hays, Bruce E. Kimmel, Lillian Ho
  • Antibodies and methods for making and using them
    Patent number: 8945550
    Abstract: The invention provides antibodies, including chimeric human antibodies, recombinant antibodies, synthetic anti-bodies, and the nucleic acids encoding them, and methods for making and using these immunoglobulins. The invention provides recombinant and synthetic polypeptide and nucleic acid embodiments of these polypeptides and/or antibodies. The invention also provides polypeptides comprising, or consisting of, consensus human framework regions, or “Independently Consensused Frameworks (ICFs)”, nucleic acids encoding them, and libraries and kits comprising these ICFs and/or antibodies of the invention, individually and in combinatorial libraries and combinations.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: February 3, 2015
    Assignee: MMRGlobal, Inc.
    Inventors: Gerhard Frey, Bruce E. Kimmel, Abraham Anderson
  • Novel Prodrug Containing Molecule Compositions and Their Uses
    Publication number: 20150018530
    Abstract: Novel prodrug compositions and uses thereof are provided.
    Type: Application
    Filed: February 28, 2013
    Publication date: January 15, 2015
    Applicant: AMBRX, INC.
    Inventors: Zhenwei Miao, Ho Sung Cho, Bruce E. Kimmel
  • ANTIBODIES AND METHODS FOR MAKING AND USING THEM
    Publication number: 20130287766
    Abstract: The invention provides antibodies, including chimeric human antibodies, recombinant antibodies, synthetic anti-bodies, and the nucleic acids encoding them, and methods for making and using these immunoglobulins. The invention provides recombinant and synthetic polypeptide and nucleic acid embodiments of these polypeptides and/or antibodies. The invention also provides polypeptides comprising, or consisting of, consensus human framework regions, or “Independently Consensused Frameworks (ICFs)”, nucleic acids encoding them, and libraries and kits comprising these ICFs and/or antibodies of the invention, individually and in combinatorial libraries and combinations.
    Type: Application
    Filed: April 19, 2013
    Publication date: October 31, 2013
    Inventors: Gehard Frey, Bruce E. Kimmel, Abraham Anderson
  • Biosynthetic Polypeptide Fusion Inhibitors
    Publication number: 20130237474
    Abstract: Modified biosynthetic polypeptide fusion inhibitors, methods for manufacturing, and uses thereof are provided.
    Type: Application
    Filed: November 13, 2012
    Publication date: September 12, 2013
    Applicant: AMBRX, INC.
    Inventors: Roberto Mariani, Bruce E. Kimmel
  • Antibodies and methods for making and using them
    Patent number: 8465741
    Abstract: The invention provides antibodies, including chimeric human antibodies, recombinant antibodies, synthetic antibodies, and the nucleic acids encoding them, and methods for making and using these immunoglobulins. The invention provides recombinant and synthetic polypeptide and nucleic acid embodiments of these polypeptides and/or antibodies. The invention also provides polypeptides comprising, or consisting of, consensus human framework regions, or “Independently Consensused Frameworks (ICFs)”, nucleic acids encoding them, and libraries and kits comprising these ICFs and/or antibodies of the invention, individually and in combinatorial libraries and combinations.
    Type: Grant
    Filed: September 14, 2007
    Date of Patent: June 18, 2013
    Assignee: MMRGlobal, Inc.
    Inventors: Gerhard Frey, Bruce E. Kimmel, Abraham Anderson
  • Biosynthetic Polypeptide Fusion Inhibitors
    Publication number: 20120142890
    Abstract: Modified biosynthetic polypeptide fusion inhibitors, methods for manufacturing, and uses thereof are provided.
    Type: Application
    Filed: October 30, 2007
    Publication date: June 7, 2012
    Applicant: AMBRX, INC.
    Inventors: Roberto MARIANI, Bruce E. KIMMEL
  • Pegylated human interferon polypeptides
    Patent number: 8093356
    Abstract: Modified human interferon polypeptides and uses thereof are provided, including PEGylated human interferon polypeptides with one or more non-naturally encoded amino acids.
    Type: Grant
    Filed: October 26, 2007
    Date of Patent: January 10, 2012
    Assignee: Ambrx, Inc.
    Inventors: Anna-Maria A. Hays, Bruce E. Kimmel, Ho Sung Cho, Bee-Cheng Sim, David C. Litzinger, Roberto Mariani, Vadim Kraynov, Nick Knudsen, Thomas O. Daniel, Alan Koder, Stuart Bussell, Junjie Liu, Zhenwei Miao, Theresa Morrow
  • Human Interferon Molecules and Their Uses
    Publication number: 20100135959
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: June 2, 2006
    Publication date: June 3, 2010
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria A. Hays Putnam, Bruce E. Kimmel, Ho Sung Cho, Bee-Cheng Sim, David C. Litzinger, Roberto Mariani, Vadim Kraynov, Nick Knudsen, Thomas O. Daniel, Alan Koder, Stuart Bussell, Junjie Liu, Zhenwei Miao, Theresa Morrow
  • ANTIBODIES AND METHODS FOR MAKING AND USING THEM
    Publication number: 20100104553
    Abstract: The invention provides antibodies, including chimeric human antibodies, recombinant antibodies, synthetic antibodies, and the nucleic acids encoding them, and methods for making and using these immunoglobulins. The invention provides recombinant and synthetic polypeptide and nucleic acid embodiments of these polypeptides and/or antibodies. The invention also provides polypeptides comprising, or consisting of, consensus human framework regions, or “Independently Consensused Frameworks (ICFs)”, nucleic acids encoding them, and libraries and kits comprising these ICFs and/or antibodies of the invention, individually and in combinatorial libraries and combinations.
    Type: Application
    Filed: September 14, 2007
    Publication date: April 29, 2010
    Inventors: Gerhard FREY, Bruce E. Kimmel, Abraham Anderson
  • Biosynthetic Polypeptides Utilizing Non-Naturally Encoded Amino Acids
    Publication number: 20100048871
    Abstract: Modified biosynthetic polypeptide molecules, methods for manufacturing, and uses thereof are provided.
    Type: Application
    Filed: November 4, 2009
    Publication date: February 25, 2010
    Applicant: AMBRX, INC.
    Inventors: Ho Sung CHO, Thomas O. DANIEL, Anna-Maria HAYS, Troy E. WILSON, David C. LITZINGER, Roberto MARIANI, Bruce E. KIMMEL, William M. KEEFE
  • Biosynthetic polypeptides utilizing non-naturally encoded amino acids
    Patent number: 7638299
    Abstract: Modified biosynthetic polypeptide molecules, methods for manufacturing, and uses thereof are provided.
    Type: Grant
    Filed: July 21, 2005
    Date of Patent: December 29, 2009
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Anna-Maria Hays, Troy E. Wilson, David C. Litzinger, Roberto Mariani, Bruce E. Kimmel, William M. Keefe
  • Antigen-binding polypeptides and their uses
    Patent number: 7632924
    Abstract: Novel antigen-binding polypeptides (ABP) and uses thereof are provided.
    Type: Grant
    Filed: June 17, 2005
    Date of Patent: December 15, 2009
    Assignee: Ambrx, Inc.
    Inventors: Ho Sung Cho, Thomas O. Daniel, Troy E. Wilson, Thomas P. Cujec, Feng Tian, Anna-Maria Hays, Bruce E. Kimmel, Lillian Ho
  • ANTIBODIES AND METHODS FOR MAKING AND USING THEM
    Publication number: 20090285813
    Abstract: The invention provides antibodies, including chimeric human antibodies, recombinant antibodies, synthetic anti-bodies, and the nucleic acids encoding them, and methods for making and using these immunoglobulins. The invention provides recombinant and synthetic polypeptide and nucleic acid embodiments of these polypeptides and/or antibodies. The invention also provides polypeptides comprising, or consisting of, consensus human framework regions, or “Independently Consensused Frameworks (ICFs)”, nucleic acids encoding them, and libraries and kits comprising these ICFs and/or antibodies of the invention, individually and in combinatorial libraries and combinations.
    Type: Application
    Filed: June 18, 2009
    Publication date: November 19, 2009
    Inventors: GERHARD FREY, BRUCE E. KIMMEL, ABRAHAM ANDERSON
  • Biosynthetic Polypeptide Fusion Inhibitors
    Publication number: 20090088365
    Abstract: Modified biosynthetic polypeptide fusion inhibitors, methods for manufacturing, and uses thereof are provided.
    Type: Application
    Filed: November 1, 2006
    Publication date: April 2, 2009
    Inventors: Roberto Mariani, Bruce E. Kimmel
  • Human Interferon Molecules and Their Uses
    Publication number: 20080132681
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 26, 2007
    Publication date: June 5, 2008
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria A. HAYS, Bruce E. KIMMEL, Ho Sung CHO, Bee-Cheng SIM, David C. LITZINGER, Roberto MARIANI, Vadim KRAYNOV, Nick Knudsen, Thomas O. DANIEL, Alan KODER, Stuart BUSSELL, Junjie LIU, Zhenwei MIAO, Theresa MORROW
  • Human Interferon Molecules and Their Uses
    Publication number: 20080119640
    Abstract: Modified human interferon polypeptides and uses thereof are provided.
    Type: Application
    Filed: October 26, 2007
    Publication date: May 22, 2008
    Applicant: AMBRX, INC.
    Inventors: Anna-Maria A. HAYS, Bruce E. KIMMEL, Ho Sung CHO, Bee-Cheng SIM, David C. LITZINGER, Roberto MARIANI, Vadim KRAYNOV, Nick Knudsen, Thomas O. DANIEL, Alan KODER, Stuart BUSSELL, Junjie LIU, Zhenwei MIAO, Theresa MORROW
  • Biosynthetic Polypeptide Fusion Inhibitors
    Publication number: 20080113408
    Abstract: Modified biosynthetic polypeptide fusion inhibitors, methods for manufacturing, and uses thereof are provided.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 15, 2008
    Applicant: AMBRX, INC.
    Inventors: Roberto MARIANI, Bruce E. KIMMEL
  • Biosynthetic Polypeptide Fusion Inhibitors
    Publication number: 20080112943
    Abstract: Modified biosynthetic polypeptide fusion inhibitors, methods for manufacturing, and uses thereof are provided.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 15, 2008
    Applicant: AMBRX, INC.
    Inventors: Roberto MARIANI, Bruce E. KIMMEL
  • Method to diagnose hereditary hemochromatosis
    Patent number: 5753438
    Abstract: New genetic markers for the presence of a mutation in the common hereditary hemochromatosis (HH) gene are disclosed. The multiplicity of markers permits definition of genotypes characteristic of carriers and homozygotes containing this mutation in their genomic DNA.
    Type: Grant
    Filed: May 8, 1995
    Date of Patent: May 19, 1998
    Assignee: Mercator Genetics, Inc.
    Inventors: Dennis T. Drayna, John N. Feder, Andreas Gnirke, Bruce E. Kimmel, Winston J. Thomas, Roger K. Wolff