Abstract: An apparatus for separating at least two discrete volumes of a composite liquid into at least a first component and a second component, comprising a well provided on a rotor near the axis of rotation for receiving a relatively rare blood component, such as mesenchymal stem cells (MSC), or for receiving a fluid that can be used multiple times, such as a washing solution. The well is placed radially outwardly from the axis of rotation and radially inwardly from cavity, which receives bags containing blood or another biologic fluid. The well is placed in a low centrifugal force region relative to the position of the cavity.

Abstract: An apparatus for separating at least two discrete volumes of a composite liquid into at least a first component and a second component, comprising an asymmetrical junction or manifold in the blood bag and tubing set inhibits errors when the bags and tubes are loaded into the device.

Abstract: A disposable cartridge for use in extracorporeal blood perfusions systems that have a control unit for controlling the flow of fluids. The cartridge has a housing defining a plurality of internal passageways that connect to a cardiopulmonary circuit, a cardioplegia circuit and a suction circuit. The cartridge may be fitted with one or more of a bubble trap, a filter, and a valve.

Abstract: An extracorporeal blood perfusion system includes a disposable assembly and a control unit having a control interface region. The interface region includes pump assemblies for selective pumping of venous blood, arterial blood, cardioplegia solution, suctioned blood and blood removed from the left ventricle. Valve assemblies control the flow of fluids through the assembly and to/from the patient and sensors monitor various fluid parameters including temperature and pressure within the various fluid circuits. The user interface is a functional screen interface for effecting the operation of the control unit and valve assemblies. The screen interface may be a touch screen having objects that corresponds to the component interface region. The display may be selectively controlled to provide graphic depictions of disposable assembly components with corresponding narrative instructions.

Abstract: A disposable cartridge for use in extracorporeal blood perfusions systems that have a control unit for controlling the flow of fluids. The cartridge has a housing defining a plurality of internal passageways that connect to a cardiopulmonary circuit, a cardioplegia circuit and a suction circuit. The cartridge may be fitted with one or more of a bubble trap, a filter, and a valve.

Abstract: A system and method provide for the interconnection of a medical fluid processing system with at least one patient temperature control pad positionable on a patient. Includable in the system is at least one connector interconnected and/or interconnectable to the medical fluid processing system and at least one connector interconnected and/or interconnectable to the at least one temperature control pad, wherein the connectors include an orientation device which provides for interconnection of the connectors at a predetermined orientation.

Abstract: An improved patient temperature exchange system and method is disclosed for use with one or more interconnectable patient contact pads. In one embodiment, the system includes a circulating pump for drawing fluid through the interconnected pad(s) under negative pressure, and for pumping the fluid through one of more heat exchange devices into a circulating reservoir. Also included in the system is a system controller specially configured for controlling the one or more heat exchange devices. The controller is further configured to employ one or more algorithms for adding and removing heat in a predetermined manner. One algorithm may include first and second control terms which provide for a theoretical heat transfer rate as well as instructions for changing temperature in an expedient manner while reducing isolations and overshoots.

Abstract: A connector apparatus employable in a patient temperature control system includes a connection end which is employable for connecting to at least one other connector in the system. Includable in the connection end is an orientation device configured to align the connectors and provide for interconnection only at a predetermined orientation. The connector may be configured as either a male or female style connector and include one or more engagement devices or surfaces for engaging with another connector.

Abstract: An improved patient temperature exchange system and method is disclosed for use with one or more interconnectable patient contact pads. In one embodiment, the system includes a circulating pump for drawing fluid through the interconnected pad(s) under negative pressure, and for pumping the fluid through one of more heat exchange devices into a circulating reservoir. A make-up reservoir may be provided for gravity fluid flow into the circulating reservoir during the filling of the interconnectable pad(s) and for receiving fluid upon emptying of the interconnectable pad(s). During normal heating/cooling operations, the circulated fluid does not pass through the make-up reservoir, thereby yielding a highly responsive system. The make-up and circulatory reservoirs may be directly interconnected, with the make-up reservoir maintained at atmospheric pressure (e.g. via a non-spill vent).

Abstract: A connector apparatus employable in a patient temperature control system includes a connection end which is employable for connecting to at least one other connector in the system. Includable in the connection end is an orientation device configured to align the connectors and provide for interconnection only at a predetermined orientation. The connector may be configured as either a male or female style connector and include one or more engagement devices or surfaces for engaging with another connector.

Abstract: A system and method provide for the interconnection of a medical fluid processing system with at least one patient temperature control pad positionable on a patient. Includable in the system is at least one connector interconnected and/or interconnectable to the medical fluid processing system and at least one connector interconnected and/or interconnectable to the at least one temperature control pad, wherein the connectors include an orientation device which provides for interconnection of the connectors at a predetermined orientation.

Abstract: An improved patient temperature exchange system and method is disclosed for use with one or more interconnectable patient contact pads. In one embodiment, the system includes a circulating pump for drawing fluid through the interconnected pad(s) under negative pressure, and for pumping the fluid through one of more heat exchange devices into a circulating reservoir. A make-up reservoir may be provided for gravity fluid flow into the circulating reservoir during the filling of the interconnectable pad(s) and for receiving fluid upon emptying of the interconnectable pad(s). During normal heating/cooling operations, the circulated fluid does not pass through the make-up reservoir, thereby yielding a highly responsive system. The make-up and circulatory reservoirs may be directly interconnected, with the make-up reservoir maintained at atmospheric pressure (e.g. via a non-spill vent).

Abstract: An improved patient temperature exchange system and method is disclosed for use with one or more interconnectable patient contact pads. In one embodiment, the system includes a circulating pump for drawing fluid through the interconnected pad(s) under negative pressure, and for pumping the fluid through one of more heat exchange devices into a circulating reservoir. Also included in the system is a system controller specially configured for controlling the one or more heat exchange devices. The controller is further configured to employ one or more algorithms for adding and removing heat in a predetermined manner. One algorithm may include first and second control terms which provide for a theoretical heat transfer rate as well as instructions for changing temperature in an expedient manner while reducing isolations and overshoots.

Abstract: An improved patient temperature exchange system and method is disclosed for use with one or more interconnectable patient contact pads. In one embodiment, the system includes a circulating pump for drawing fluid through the interconnected pad(s) under negative pressure, and for pumping the fluid through one of more heat exchange devices into a circulating reservoir. A make-up reservoir may be provided for gravity fluid flow into the circulating reservoir during the filling of the interconnectable pad(s) and for receiving fluid upon emptying of the interconnectable pad(s). During normal heating/cooling operations, the circulated fluid does not pass through the make-up reservoir, thereby yielding a highly responsive system. The make-up and circulatory reservoirs may be directly interconnected, with the make-up reservoir maintained at atmospheric pressure (e.g. via a non-spill vent).

Abstract: An improved patient temperature exchange system and method is disclosed for use with one or more interconnectable patient contact pads. In one embodiment, the system includes a circulating pump for drawing fluid through the interconnected pad(s) under negative pressure, and for pumping the fluid through one of more heat exchange devices into a circulating reservoir. A make-up reservoir may be provided for gravity fluid flow into the circulating reservoir during the filling of the interconnectable pad(s) and for receiving fluid upon emptying of the interconnectable pad(s). During normal heating/cooling operations, the circulated fluid does not pass through the make-up reservoir, thereby yielding a highly responsive system. The make-up and circulatory reservoirs may be directly interconnected, with the make-up reservoir maintained at atmospheric pressure (e.g. via a non-spill vent).

Abstract: A system for controlling and monitoring the extracorporeal circulation of fluids, which is particularly useful in controlling and monitoring the circulation of blood and cardioplegia solution in surgical procedures. A set of perfusion assemblies are mounted in a transportable console, each perfusion assembly having a separable pump and control module pod. Virtually all the instrumentation for the monitoring and controlling of the pump and the fluid being pumped by that perfusion assembly are present on the pump and control module pod for that perfusion assembly, without the need for any separate control screen. Further, the perfusion assembly uses removable circuit cards and associated instrumentation strips to custom configure the perfusion assembly for each application. The perfusion assembly thereby provides complete information at a glance and complete control of the perfusion assembly by using dedicated controls that are grouped to each perfusion assembly.