Patents by Inventor Bruce Francis

Bruce Francis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230282375
    Abstract: A Control Neutron Absorber (CNA) assembly for a microreactor that produces nuclear energy is disclosed. The CNA assembly includes a housing, a CNA rod, and a burnable absorber. The housing includes an inner housing and an outer housing. The inner housing is configured to receive a CNA rod. The outer housing extends coaxially with the inner housing and is positioned radially outward and offset from the inner housing defining a cavity therebetween. The CNA rod includes a neutron absorbing rod including a first neutron absorbing material. The neutron absorbing rod is positioned within the inner housing and is configured to move axially relative to the inner housing. The burnable absorber includes a second neutron absorbing material, exhibits a neutron absorbing strength that is less than that of the neutron absorbing rod, is positioned within the inner housing, and is configured to receive the neutron absorbing rod therein.
    Type: Application
    Filed: March 6, 2023
    Publication date: September 7, 2023
    Inventors: Travis L. Lange, Yasir Arafat, Benjamin A. Baker, Stanley Blaine Grover, Jeffrey Donald Jones, Lucas Avery Andrew, Mathew Ryan Floyd, Kyle Bruce Francis, Tarrin Scott Funderburg
  • Patent number: 10710992
    Abstract: The present disclosure relates to substituted pyridinones, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: July 14, 2020
    Assignee: Zenith Epigenetics Ltd.
    Inventors: May Xiaowu Jiang, Bruce Francis Molino, Shuang Liu, Ruifang Wang, Bryan Cordell Duffy, John Frederick Quinn, Gregory Steven Wagner
  • Patent number: 10327818
    Abstract: A spinal adjustment system which includes at least three implant modules, wherein each implant module includes: an engagement apparatus for engaging the implant module with a vertebra; and a semirigid, resilient elongated force application means which in use is secured to said engagement apparatus and extends from one implant module to the or each adjacent implant module; wherein: said force application means in use engages said the or each adjacent implant module such that said force application means can slide relative thereto in the plane of the force application means; each force application means in use applies a lifting force to the corresponding implant module and said at least three implant modules together in use apply a rotational force to said system; and the force application means extending from one implant module to an adjacent implant module extends alongside the force application means extending from said adjacent implant module to said one implant module.
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: June 25, 2019
    Inventor: Bruce Francis Hodgson
  • Patent number: 10179125
    Abstract: The disclosure relates to substituted pyridines, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: January 15, 2019
    Assignee: Zenith Epigenetics Ltd.
    Inventors: May Xiaowu Jiang, Bruce Francis Molino, Shuang Liu, Ruifang Wang, Bryan Cordell Duffy, John Frederick Quinn, Gregory Steven Wagner
  • Patent number: 9861637
    Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: January 9, 2018
    Assignee: Zenith Epigenetics Ltd.
    Inventors: Shuang Liu, Bryan Cordell Duffy, John Frederick Quinn, May Xiaowu Jiang, Ruifang Wang, Gregory Scott Martin, He Zhao, Bruce Francis Molino, Peter Ronald Young
  • Publication number: 20170360765
    Abstract: The disclosure relates to substituted pyridines, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Application
    Filed: December 1, 2015
    Publication date: December 21, 2017
    Inventors: May Xiaowu Jiang, Bruce Francis Molino, Shuang Liu, Ruifang Wang, Bryan Cordell Duffy, John Frederick Quinn, Gregory Steven Wagner
  • Publication number: 20170320866
    Abstract: The present disclosure relates to substituted pyridinones, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Application
    Filed: December 1, 2015
    Publication date: November 9, 2017
    Inventors: May Xiaowu Jiang, Bruce Francis Molino, Shuang Liu, Ruifang Wang, Bryan Cordell Duffy, John Frederick Quinn, Gregory Steven Wagner
  • Publication number: 20170181771
    Abstract: A spinal adjustment system which includes at least three implant modules, wherein each implant module includes: engaging means for engaging the implant module with a vertebra; and a semirigid, resilient elongated force application means which in use is secured to said engaging means and extends from one implant module to the or each adjacent implant module; wherein: said force application means in use engages said the or each adjacent implant to module such that said force application means can slide relative thereto in the plane of the force application means; each force application means in use applies a lifting force to the corresponding implant module and said at least three implant modules together in use apply a rotational force to said system; and the force application means extending from one implant module to an adjacent implant module extends alongside the force application means extending from said adjacent implant module to said one implant module.
    Type: Application
    Filed: March 14, 2017
    Publication date: June 29, 2017
    Inventor: Bruce Francis Hodgson
  • Publication number: 20170143731
    Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Application
    Filed: February 3, 2017
    Publication date: May 25, 2017
    Inventors: Shuang Liu, Bryan Cordell Duffy, John Frederick Quinn, May Xiaowu Jiang, Ruifang Wang, Gregory Scott Martin, He Zhao, Bruce Francis Molino, Peter Ronald Young
  • Patent number: 9598367
    Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: March 21, 2017
    Assignee: Zenith Epigenetics Ltd.
    Inventors: Shuang Liu, Bryan Cordell Duffy, John Frederick Quinn, May Xiaowu Jiang, Ruifang Wang, Gregory Scott Martin, He Zhao, Bruce Francis Molino, Peter Ronald Young
  • Patent number: 9532501
    Abstract: A conveyor includes a frame, at least two arms at least one of which is movably mounted to the frame, at least two rails wherein each rail is coupled to an end of one of said at least two arms, at least two belts wherein each belt is rotatably mounted on one of said at least two rails such that the belts are capable of engaging plants therebetween and moving the plants along a conveyor axis, and one or more bias members which are configured to bias said at least one movable arm toward the other one of said at least two arms. The conveyor further comprises an expanding mechanism which is configured to exert an outward force on said at least one movable arm upon engagement so that said at least one movable arm move away from another arm.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: January 3, 2017
    Assignee: Weyerhaeuser NR Company
    Inventors: Bruce Francis, William Wells, Jimmy Lee Stokes
  • Patent number: 9483685
    Abstract: A method of classifying ciliary motion includes receiving digital video data representing the ciliary motion generated by an image capture device, wherein the digital video data includes a plurality of frames. The method further includes receiving an indication of a region of interest applicable to each of the frames, wherein the region of interest includes a plurality of pixels in each of the frames, calculating time series elemental motion data for at least one elemental motion parameter for the region of interest based on the digital video data, and using the time series elemental motion data to classify the ciliary motion.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: November 1, 2016
    Assignee: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Chakra S. Chennubhotla, Shannon P. Quinn, John R. Durkin, Maliha Zahid, Richard John Bruce Francis, Cecilia Wen Ya Lo
  • Publication number: 20160130228
    Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Application
    Filed: January 15, 2016
    Publication date: May 12, 2016
    Inventors: Shuang Liu, Bryan Cordell Duffy, John Frederick Quinn, May Xiaowu Jiang, Ruifang Wang, Gregory Scott Martin, He Zhao, Bruce Francis Molino, Peter Ronald Young
  • Patent number: 9271978
    Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: March 1, 2016
    Assignee: Zenith Epigenetics Corp.
    Inventors: Shuang Liu, Bryan Cordell Duffy, John Frederick Quinn, May Xiaowu Jiang, Ruifang Wang, Gregory Scott Martin, He Zhao, Bruce Francis Molino, Peter Ronald Young
  • Publication number: 20150310254
    Abstract: A method of classifying ciliary motion includes receiving digital video data representing the ciliary motion generated by an image capture device, wherein the digital video data includes a plurality of frames. The method further includes receiving an indication of a region of interest applicable to each of the frames, wherein the region of interest includes a plurality of pixels in each of the frames, calculating time series elemental motion data for at least one elemental motion parameter for the region of interest based on the digital video data, and using the time series elemental motion data to classify the ciliary motion.
    Type: Application
    Filed: April 28, 2015
    Publication date: October 29, 2015
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventors: CHAKRA S. CHENNUBHOTLA, SHANNON P. QUINN, JOHN R. DURKIN, MALIHA ZAHID, RICHARD JOHN BRUCE FRANCIS, CECILIA WEN YA LO
  • Publication number: 20150142058
    Abstract: Spinal adjustment system including at least three implant modules, at least one of the implant modules being a first implant module including: means for engaging the first implant module with a first vertebra; and first force application means; characterised in that: the first force application means is adapted to engage with a second implant module engaged with a second vertebra superior to the first vertebra; the first force application means is adapted to also engage with a third implant module engaged with a third vertebra inferior to the first vertebra; and the first implant module includes means of adjusting the force applied to the first vertebra by the first force application means.
    Type: Application
    Filed: June 13, 2013
    Publication date: May 21, 2015
    Inventor: Bruce Francis Hodgson
  • Publication number: 20150096771
    Abstract: A conveyor includes a frame, at least two arms at least one of which is movably mounted to the frame, at least two rails wherein each rail is coupled to an end of one of said at least two arms, at least two belts wherein each belt is rotatably mounted on one of said at least two rails such that the belts are capable of engaging plants therebetween and moving the plants along a conveyor axis, and one or more bias members which are configured to bias said at least one movable arm toward the other one of said at least two arms. The conveyor further comprises an expanding mechanism which is configured to exert an outward force on said at least one movable arm upon engagement so that said at least one movable arm move away from another arm.
    Type: Application
    Filed: October 4, 2013
    Publication date: April 9, 2015
    Applicant: WEYERHAEUSER NR COMPANY
    Inventors: Bruce Francis, William Wells, Jimmy Lee Stokes
  • Publication number: 20140179648
    Abstract: The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
    Type: Application
    Filed: December 19, 2013
    Publication date: June 26, 2014
    Applicant: RVX Therapeutics Inc.
    Inventors: Shuang Liu, Bryan Cordell Duffy, John Frederick Quinn, May Xiaowu Jiang, Ruifang Wang, Gregory Scott Martin, He Zhao, Bruce Francis Molino, Peter Ronald Young
  • Patent number: 7140339
    Abstract: A kick start switch modification kit and method for modifying an electric starter system on a motorcycle to a foot-operated electric starter simulating the classic foot operated kick start mechanism. Novel components which are contained in the modification kit include a foot pedal assembly, a rotating shaft, a switch engaging cam, a limit switch and a cover body having screw holes through which fasteners can pass which fasteners are in turn screwed into the cycle body where the classic kick start mechanism would be located.
    Type: Grant
    Filed: March 21, 2006
    Date of Patent: November 28, 2006
    Inventor: Bruce Francis Smith
  • Patent number: 7113575
    Abstract: An ADSL/POTS filter arrangement includes a filter and a switchable return loss correction circuit coupled to one side of the filter. The switchable return loss correction circuit includes a resistor and an inductor connected in parallel, a polarity insensitive solid state switch, and a capacitor connected in series between the switch and the parallel-connected resistor and inductor. The switchable return loss correction circuit is switched on by the polarity insensitive solid state switch which is controlled by a line sensor depending on whether the POTS telephone is on or off-hook.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: September 26, 2006
    Assignee: Alcatel
    Inventor: Bruce Francis Orr