Patents by Inventor Bruce Hamaker

Bruce Hamaker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10852297
    Abstract: An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: December 1, 2020
    Assignees: Rush University Medical Center, Purdue Research Foundation
    Inventors: Ali Keshavarzian, Sander de Kivit, Bruce Hamaker
  • Publication number: 20190178872
    Abstract: An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided.
    Type: Application
    Filed: February 8, 2019
    Publication date: June 13, 2019
    Applicants: Rush University Medical Center, Purdue Research Foundation
    Inventors: Ali Keshavarzian, Sander de Kivit, Bruce Hamaker
  • Patent number: 10222370
    Abstract: An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: March 5, 2019
    Assignees: Rush University Medical Center, Purdue Research Foundation
    Inventors: Ali Keshavarzian, Sander de Kivit, Bruce Hamaker
  • Publication number: 20170184569
    Abstract: An assay and a method for identifying a prebiotic to treat a subject in need thereof to promote intestinal barrier integrity or to blunt an inflammatory response are provided.
    Type: Application
    Filed: April 6, 2015
    Publication date: June 29, 2017
    Applicants: Rush University Medical Center, Purdue Research Foundation
    Inventors: Ali Keshavarzian, Sander de Kivit, Bruce Hamaker
  • Publication number: 20140212494
    Abstract: A method of treating constipation is disclosed. The method includes administering starch-entrapped microbeads.
    Type: Application
    Filed: September 24, 2012
    Publication date: July 31, 2014
    Inventors: Bruce Hamaker, Ali Keshavarzian, Mark D. Cisneros, Amandeep Kaur, Heather Rasmussen
  • Publication number: 20070196437
    Abstract: Compositions which provide slowly digestible starch and a source of fermentable dietary fiber. Microparticles in which starch is entrapped in a crosslinked matrix to provide dietary benefit. Such microparticles are used to deliver glucose to targeted regions in the small intestine for beneficial physiological effects, and fermentable dietary fiber to the colon to improve colon health and to treat diseases of the colon. Microparticles can be employed to selectively deliver fermentable dietary fiber to targeted portions of the colon. A method for making the microparticles is provided as well as methods for using the microparticles for controlled digestion of starch on ingestion in the small intestine and methods for using the microparticles to deliver dietary fiber. The microparticles with entrapped starch provide a low glycemic index and extended glucose release in food products and food ingredients.
    Type: Application
    Filed: December 6, 2006
    Publication date: August 23, 2007
    Inventors: BRUCE HAMAKER, MAHESH VENKATACHALAM, GENYI ZHANG, ALI KESHAVARZIAN, DEVIN ROSE
  • Publication number: 20060257977
    Abstract: The invention provides processes to make slowly digestible starches from native and commercial starches. Slowly digestible starches are prepared by controlled hydrolysis of gelatinized starch by alpha amylase. The slowly digestible starches have a range of starch digestion rates and fall between normal, untreated commercial and native starch, and commercial resistant starches. The slowly digestible starches provide a range of starch functionalities. These slow digesting starches retain their digestion characteristic after cooling, and can used in a range of processed food products to modulate the rapid glucose release typical of many processed starchy foods. Edible products incorporating slowly digestible starch will exhibit lower glycemic index and increase satiety. The invention provides solid and liquid food, nutritional, and drug preparations containing the slowly digestible starch.
    Type: Application
    Filed: January 28, 2004
    Publication date: November 16, 2006
    Inventors: Bruce Hamaker, Xian-Zhong Han
  • Publication number: 20050106300
    Abstract: A method of processing a starchy plant material to produce a processed material having an increased solubility in alcohol comprising mixing the starchy plant material and a liquid at an elevated temperature to form a mixture and applying shear force to the mixture to produce the processed material. The processed material is one or more or a combination or complex of protein, zein, and oil.
    Type: Application
    Filed: June 30, 2004
    Publication date: May 19, 2005
    Inventors: Li-Fu Chen, Qin Xu, Bruce Hamaker