Abstract: A coiled stent graft, including a thrombolytic agent, is positionable within an AV fistula and optionally into one or both of the artery and the vein (6) to help reduce or eliminate blockages within the blood vessel at the junction between the AV fistula and the blood vessel.

Abstract: A coiled stent graft (10), including a thrombolytic agent, is positionable within an AV fistula (4) and optionally into one or both of the artery (9) and the vein (6) to help reduce or eliminate blockages within the blood vessel at the junction (8) between the AV fistula and the blood vessel.

Abstract: A prosthesis, for use within a hollow body structure of a patient, comprises a coiled body having a radially-extending openings, the coiled body being movable from a radially-contracted state to a radially-expanded state. A material extends along a coiled path along the entire coiled body. A dispensable, biologically active agent is associated with at least one of the coiled body and material. The material may comprise a coiled sleeve of material having inner and outer surfaces, the inner surface defining a sleeve interior containing the coiled body. The dispensable agent may be, for example, on the outer surface of the material, incorporated into the material to create an agent/material matrix, or on the inner surface of the material or within the sleeve interior.

Abstract: A covered, coiled drug delivery stent (145) includes a coiled, radially-expandable stent wall or body (139) with a porous covering overlying the outer surface (139A) of the stent body. A drug (147) may be associated with the porous covering by, for example, being in the form of a porous covering/drug matrix (141) or being a layer above or below the porous covering. Structure may be used to delay the migration of the drug to the patient by, for example, using a protective layer (143) to cover the stent body, porous covering, and drug. The protective layer may be removed by being biodegradable, or by being at least partially pulled off of the structure. The drug may be an integral part of a biodegradable material so that the drug is exposed only when the biodegradable material biodegrades. The drug may also be within biodegradable microencapsulation material.