Patents by Inventor Bruce Ksander

Bruce Ksander has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ABCB5(+) STEM CELLS FOR TREATING OCULAR DISEASE
    Publication number: 20220118024
    Abstract: Various aspects and embodiments of the present invention are directed to methods of treating a subject having an ocular condition, methods of isolating ocular stem cells, methods of selecting and/or producing ocular grafts for transplantation, and methods of promoting ocular cell regeneration as well as to grafts and preparations containing isolated ocular stem cells characterized by the expression of ABCB5 on their cell surface.
    Type: Application
    Filed: September 27, 2021
    Publication date: April 21, 2022
    Applicants: The United States of America as represented by the Department of Veterans Affairs, Schepens Eye Research Institute, Children's Medical Center Corporation
    Inventors: Markus H. Frank, Natasha Y. Frank, Bruce Ksander, Paraskevi Evi Kolovou
  • ABCB5(+) stem cells for treating ocular disease
    Patent number: 11129854
    Abstract: Various aspects and embodiments of the present invention are directed to methods of treating a subject having an ocular condition, methods of isolating ocular stem cells, methods of selecting and/or producing ocular grafts for transplantation, and methods of promoting ocular cell regeneration as well as to grafts and preparations containing isolated ocular stem cells characterized by the expression of ABCB5 on their cell surface.
    Type: Grant
    Filed: October 30, 2017
    Date of Patent: September 28, 2021
    Assignees: Schepens Eye Research Institute, Children's Medical Center Corporation, The United States of America as Represented by the Department of Veterans Affairs
    Inventors: Markus H. Frank, Natasha Y. Frank, Bruce Ksander, Paraskevi Evi Kolovou
  • AAV2-MEDIATED GENE DELIVERY OF SFASL AS A NEUROPROTECTIVE THERAPY IN GLAUCOMA
    Publication number: 20190240353
    Abstract: Methods for treating glaucoma and/or Fas ligand-dependent inflammatory conditions in a subject using soluble Fas ligand (sFasL) or a fragment thereof, which may be rAAV-mediated delivery of sFasL or a fragment thereof to a subject.
    Type: Application
    Filed: July 5, 2017
    Publication date: August 8, 2019
    Applicants: University of Massachusetts, Massachusetts Eye and Ear Infirmary
    Inventors: Ann Marshak-Rothstein, Meredith Gregory-Ksander, Bruce Ksander
  • ABCB5(+) STEM CELLS FOR TREATING OCULAR DISEASE
    Publication number: 20180064762
    Abstract: Various aspects and embodiments of the present invention are directed to methods of treating a subject having an ocular condition, methods of isolating ocular stem cells, methods of selecting and/or producing ocular grafts for transplantation, and methods of promoting ocular cell regeneration as well as to grafts and preparations containing isolated ocular stem cells characterized by the expression of ABCB5 on their cell surface.
    Type: Application
    Filed: October 30, 2017
    Publication date: March 8, 2018
    Applicants: VA Boston Healthcare System, Schepens Eye Research Institute, Children's Medical Center Corporation
    Inventors: Markus H. Frank, Natasha Y. Frank, Bruce Ksander, Paraskevi Evi Kolovou
  • ABCB5(+) stem cells for treating ocular disease
    Patent number: 9801912
    Abstract: Various aspects and embodiments of the present invention are directed to methods of treating a subject having an ocular condition, methods of isolating ocular stem cells, methods of selecting and/or producing ocular grafts for transplantation, and methods of promoting ocular cell regeneration as well as to grafts and preparations containing isolated ocular stem cells characterized by the expression of ABCB5 on their cell surface.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: October 31, 2017
    Assignees: VA Boston Healthcare System, Schepens Eye Research Institute, Children's Medical Center Corporation
    Inventors: Markus H. Frank, Natasha Y. Frank, Bruce Ksander, Paraskevi Evi Kolovou
  • ABCB5(+) STEM CELLS FOR TREATING OCULAR DISEASE
    Publication number: 20150374756
    Abstract: Various aspects and embodiments of the present invention are directed to methods of treating a subject having an ocular condition, methods of isolating ocular stem cells, methods of selecting and/or producing ocular grafts for transplantation, and methods of promoting ocular cell regeneration as well as to grafts and preparations containing isolated ocular stem cells characterized by the expression of ABCB5 on their cell surface.
    Type: Application
    Filed: February 19, 2014
    Publication date: December 31, 2015
    Applicants: VA BOSTON HEALTHCARE SYSTEM, SCHEPENS EYE RESEARCH INSTITUTE, CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Markus H. Frank, Natasha Y. Frank, Bruce Ksander