Abstract: A method and apparatus for three dimensional (3D) computerized tomographic (CT) imaging of a region-of-interest (ROI) in an object, wherein image reconstruction processing is applied to a plurality of sets of pixels of 2D image data, each set being acquired on a pixelated 2D detector. The image reconstruction processing comprises filtering each of the acquired 2D image data sets for developing a corresponding plurality of filtered 2D images; and then 3D backprojecting the filtered 2D images into a common 3D space, thereby reconstructing in the 3D space a 3D image of the ROI in the object. In the present invention the filtering step comprises dividing the pixels of each set of the acquired 2D image data sets into first and second groups, and separately filtering the image data of each group to develop for each group it's own contribution to the corresponding filtered 2D image.