Patents by Inventor Bruce M. Williams

Bruce M. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080069805
    Abstract: Transplant of donor perfectly matched HLA hematopoietic stem cell to cure Sickle cell anemia and other anemia such as leukemia. Sterilized In vivo transplantation of clinically adequate quantities of antibiotic protected HLA vector/or insertion corrected chimera stem cells, and switching protein. Stem cells can be transfected for Hbg SS, and other proteins such as minor HLA type that may cause Graft versus host disease (GvHD) or Host versus Graft disease (HvGD Universal donor blood, Rh-negative of any HLA type can be corrected to perfectly match that of any recipient. Batch universal stem calls are grown and selectively transformed to a chimera stem cell. The chimera stem cells are incubated in a bio-reactor in growth medium also containing human growth and maturation promotion polypeptide factors. The harvest is then prepared for clinical use and transplantation into the matching recipient. Recipient's stem cells are transformed by transfection or insertion of the beta hemoglobin gene.
    Type: Application
    Filed: May 18, 2005
    Publication date: March 20, 2008
    Inventor: Bruce M. Williams
  • Patent number: 5190225
    Abstract: An apparatus wherein a blower motor mounted within a housing includes an outlet conduit fixedly mounted to the housing, with a further outlet conduit including a flexible interconnection between the outlet conduit to provide for selective aiming of granular material directed through the conduit structure. A hopper is mounted in operative association with the outlet conduit to include a valve assembly selectively opened by use of a remote cable to direct granular material into a metering tube diametrically directed through the outlet conduit. Harness structure is provided to provide for securement of the organization to a torso portion of an individual.
    Type: Grant
    Filed: July 18, 1991
    Date of Patent: March 2, 1993
    Inventor: Bruce M. Williams