Patents by Inventor Bruce Richter
Bruce Richter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240025759Abstract: Silica-coated magnetic nanoparticles with greater ability to remain dispersed, and methods of making and using silica-coated magnetic nanoparticles. The magnetic nanoparticles comprise a core and a coating, where the core comprises Fe3O4 or other magnetic material and the coating has a thickness of from about 1.5 nm to about 2 nm. The magnetic nanoparticles are useful for preparing nucleic acids for analysis, by separating nucleic acids from other components and by normalizing nucleic acid concentrations.Type: ApplicationFiled: September 30, 2021Publication date: January 25, 2024Inventors: Jeffrey Carl Braman, Natalia Novoradovskaya, David Long, Bruce Richter, Derick Lucas
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Patent number: 11511257Abstract: In embodiments, a packing material for supported liquid extraction has a sorbent media that includes synthetic silica particles. In embodiments, the synthetic silica particles can have physical properties relating to one or more of particle surface area, shape, size, or porosity. In one embodiment, synthetic silica particles have a surface area less than about 30 m2/g. In another embodiment, the synthetic silica particles have an approximately uniform particle shape. In further examples, synthetic silica particles have a particle size in a range of about 30-150 ?m inclusive or greater than about 200 ?m. In another embodiment, synthetic silica particles are arranged to have a pore size greater than about 500 Angstroms. In an embodiment, an apparatus for supported liquid extraction includes a container and a sorbent media that includes synthetic silica particles. In a further embodiment, a method for extracting target analytes through supported liquid extraction is provided.Type: GrantFiled: April 9, 2020Date of Patent: November 29, 2022Assignee: AGILENT TECHNOLOGIES, INC.Inventors: Kunqiang Jiang, Derick Lucas, Bruce Richter
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Publication number: 20200269213Abstract: In embodiments, a packing material for supported liquid extraction has a sorbent media that includes synthetic silica particles. In embodiments, the synthetic silica particles can have physical properties relating to one or more of particle surface area, shape, size, or porosity. In one embodiment, synthetic silica particles have a surface area less than about 30 m2/g. In another embodiment, the synthetic silica particles have an approximately uniform particle shape. In further examples, synthetic silica particles have a particle size in a range of about 30-150 ?m inclusive or greater than about 200 ?m. In another embodiment, synthetic silica particles are arranged to have a pore size greater than about 500 Angstroms. In an embodiment, an apparatus for supported liquid extraction includes a container and a sorbent media that includes synthetic silica particles. In a further embodiment, a method for extracting target analytes through supported liquid extraction is provided.Type: ApplicationFiled: April 9, 2020Publication date: August 27, 2020Applicant: Agilent Technologies, Inc.Inventors: Kunqiang Jiang, Derick Lucas, Bruce Richter
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Patent number: 10661250Abstract: In embodiments, a packing material for supported liquid extraction has a sorbent media that includes synthetic silica particles. In embodiments, the synthetic silica particles can have physical properties relating to one or more of particle surface area, shape, size, or porosity. In one embodiment, synthetic silica particles have a surface area less than about 30 m2/g. In another embodiment, the synthetic silica particles have an approximately uniform particle shape. In further examples, synthetic silica particles have a particle size in a range of about 30-150 ?m inclusive or greater than about 200 ?m. In another embodiment, synthetic silica particles are arranged to have a pore size greater than about 500 Angstroms. In an embodiment, an apparatus for supported liquid extraction includes a container and a sorbent media that includes synthetic silica particles. In a further embodiment, a method for extracting target analytes through supported liquid extraction is provided.Type: GrantFiled: December 19, 2018Date of Patent: May 26, 2020Assignee: AGILENT TECHNOLOGIES, INC.Inventors: Kunqiang Jiang, Derick Lucas, Bruce Richter
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Patent number: 10564076Abstract: Aspects of the present disclosure include a system for analytical sample preparation. In some embodiments, the system includes a container having disposed therein an analytical sample treatment composition including ?-cyclodextrin and/or an ?-cyclodextrin co-polymer. Also provided is a method of reducing matrix effects in an analytical sample. In some embodiments, the method includes: contacting a sample including a matrix-interfering agent and an analyte with a cyclodextrin composition to produce a matrix-cyclodextrin complex, wherein the cyclodextrin composition comprises an ?-cyclodextrin and/or an ?-cyclodextrin co-polymer; separating the complex from the contacted sample to produce a matrix-reduced composition; and detecting the analyte in the matrix-reduced composition. Kits and compositions for use in the subject systems and methods are also provided.Type: GrantFiled: June 16, 2015Date of Patent: February 18, 2020Assignee: AGILENT TECHNOLOGIES, INC.Inventors: Derick Lucas, Bruce Richter, David Long
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Publication number: 20190314786Abstract: In embodiments, a packing material for supported liquid extraction has a sorbent media that includes synthetic silica particles. In embodiments, the synthetic silica particles can have physical properties relating to one or more of particle surface area, shape, size, or porosity. In one embodiment, synthetic silica particles have a surface area less than about 30 m2/g. In another embodiment, the synthetic silica particles have an approximately uniform particle shape. In further examples, synthetic silica particles have a particle size in a range of about 30-150 ?m inclusive or greater than about 200 ?m. In another embodiment, synthetic silica particles are arranged to have a pore size greater than about 500 Angstroms. In an embodiment, an apparatus for supported liquid extraction includes a container and a sorbent media that includes synthetic silica particles. In a further embodiment, a method for extracting target analytes through supported liquid extraction is provided.Type: ApplicationFiled: December 19, 2018Publication date: October 17, 2019Applicant: Agilent Technologies, Inc.Inventors: Kunqiang Jiang, Derick Lucas, Bruce Richter
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Patent number: 10436684Abstract: Aspects of the present disclosure include a solid phase sorbent for preparation of analytical samples. The solid phase sorbent includes particles that are surface modified with an ?-cyclodextrin moiety. Also provided is a method of reducing matrix effects in an analytical sample. In some embodiments, the method includes contacting a sample comprising a matrix-interfering agent and an analyte with ?-cyclodextrin modified particles to produce a contacted sample wherein the matrix-interfering agent binds to the ?-cyclodextrin modified particles; separating the ?-cyclodextrin modified particles from the contacted sample to produce a matrix-reduced composition; and detecting the analyte in the matrix-reduced composition. Systems for practicing the subject methods are provided that include the subject solid phase sorbent.Type: GrantFiled: September 19, 2016Date of Patent: October 8, 2019Assignee: AGILENT TECHNOLOGIES, INC.Inventors: Bruce Richter, Derick Lucas, David Long, Limian Zhao
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Publication number: 20180080858Abstract: Aspects of the present disclosure include a solid phase sorbent for preparation of analytical samples. The solid phase sorbent includes particles that are surface modified with an ?-cyclodextrin moiety. Also provided is a method of reducing matrix effects in an analytical sample. In some embodiments, the method includes contacting a sample comprising a matrix-interfering agent and an analyte with ?-cyclodextrin modified particles to produce a contacted sample wherein the matrix-interfering agent binds to the ?-cyclodextrin modified particles; separating the ?-cyclodextrin modified particles from the contacted sample to produce a matrix-reduced composition; and detecting the analyte in the matrix-reduced composition. Systems for practicing the subject methods are provided that include the subject solid phase sorbent.Type: ApplicationFiled: September 19, 2016Publication date: March 22, 2018Inventors: Bruce Richter, Derick Lucas, David Long, Limian Zhao
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Publication number: 20160370357Abstract: Aspects of the present disclosure include a system for analytical sample preparation. In some embodiments, the system includes a container having disposed therein an analytical sample treatment composition including ?-cyclodextrin and/or an ?-cyclodextrin co-polymer. Also provided is a method of reducing matrix effects in an analytical sample. In some embodiments, the method includes: contacting a sample including a matrix-interfering agent and an analyte with a cyclodextrin composition to produce a matrix-cyclodextrin complex, wherein the cyclodextrin composition comprises an ?-cyclodextrin and/or an ?-cyclodextrin co-polymer; separating the complex from the contacted sample to produce a matrix-reduced composition; and detecting the analyte in the matrix-reduced composition. Kits and compositions for use in the subject systems and methods are also provided.Type: ApplicationFiled: June 16, 2015Publication date: December 22, 2016Inventors: Derick Lucas, Bruce Richter, David Long
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Patent number: 9063045Abstract: A method for pretreating and extracting a liquid sample by sorbing an aqueous liquid sample, including an organic analyte and an acid or a base, in a solid sorbent material, and at least partially neutralizing the acid or base by reaction with neutralizing ions retained on a support surface, and contacting the liquid sample-sorbed sorbent material at elevated temperature and pressure with an organic solvent to extract the analyte into said solvent, preferably in a vessel having an extraction chamber with a zirconium metal interior surface.Type: GrantFiled: August 5, 2013Date of Patent: June 23, 2015Assignee: Dionex CorporationInventors: Kannan Srinivasan, Bruce Richter, Christopher A. Pohl, Brett Murphy, Brian Dorich, SM Rahmat Ullah
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Publication number: 20130316466Abstract: A method for pretreating and extracting a liquid sample by sorbing an aqueous liquid sample, including an organic analyte and an acid or a base, in a solid sorbent material, and at least partially neutralizing the acid or base by reaction with neutralizing ions retained on a support surface, and contacting the liquid sample-sorbed sorbent material at elevated temperature and pressure with an organic solvent to extract the analyte into said solvent, preferably in a vessel having an extraction chamber with a zirconium metal interior surface.Type: ApplicationFiled: August 5, 2013Publication date: November 28, 2013Inventors: Kannan SRINIVASAN, Bruce RICHTER, Christopher A. POHL, Brett MURPHY, Brian DORICH, SM Rahmat ULLAH
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Patent number: 8507292Abstract: A method for pretreating and extracting a liquid sample by sorbing an aqueous liquid sample, including an organic analyte and an acid or a base, in a solid sorbent material, and at least partially neutralizing the acid or base by reaction with neutralizing ions retained on a support surface, and contacting the liquid sample-sorbed sorbent material at elevated temperature and pressure with an organic solvent to extract the analyte into said solvent, preferably in a vessel having an extraction chamber with a zirconium metal interior surface.Type: GrantFiled: July 1, 2011Date of Patent: August 13, 2013Assignee: Dionex CorporationInventors: Kannan Srinivasan, Bruce Richter, Christopher A. Pohl, Brett Murphy, Brian Dorich, S. M. Rahmat Ullah
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Publication number: 20120028368Abstract: A method for pretreating and extracting a liquid sample by sorbing an aqueous liquid sample, including an organic analyte and an acid or a base, in a solid sorbent material, and at least partially neutralizing the acid or base by reaction with neutralizing ions retained on a support surface, and contacting the liquid sample-sorbed sorbent material at elevated temperature and pressure with an organic solvent to extract the analyte into said solvent, preferably in a vessel having an extraction chamber with a zirconium metal interior surface.Type: ApplicationFiled: July 1, 2011Publication date: February 2, 2012Applicant: Dionex CorporationInventors: Kannan Srinivasan, Bruce Richter, Christopher A. Pohl, Brett Murphy, Brian Dorich, S.M. Rahmat Ullah
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Publication number: 20090221079Abstract: A method for pretreating and extracting a liquid sample by sorbing an aqueous liquid sample, including an organic analyte and an acid or a base, in a solid sorbent material, and at least partially neutralizing the acid or base by reaction with neutralizing ions retained on a support surface, and contacting the liquid sample-sorbed sorbent material at elevated temperature and pressure with an organic solvent to extract the analyte into said solvent, preferably in a vessel having an extraction chamber with a zirconium metal interior surface.Type: ApplicationFiled: February 28, 2008Publication date: September 3, 2009Applicant: DIONEX CORPORATIONInventors: Kannan Srinivasan, Bruce Richter, Christopher A. Pohl, Brett Murphy, Brian Dorich, S.M. Rahmat Ullah
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Patent number: 5817394Abstract: This invention relates to a fibrous laminated material wherein a first fibrous layer comprising a plurality of staple fibers or continuous filaments of a thermoplastic material and a second fibrous layer comprising a plurality of staple fibers or continuous filaments of two or more thermoplastic or other materials are bonded together in a spaced apart bonding pattern having apertures formed therein to form a fibrous laminate having improved liquid distribution and management properties as well as enhanced comfort and softness when placed in contact with human skin. Also disclosed are a method and apparatus for making such a fibrous laminate, as well as absorbent articles incorporating such fibrous laminate.Type: GrantFiled: August 10, 1995Date of Patent: October 6, 1998Assignee: Kimberly-Clark CorporationInventors: Mir Inayeth Alikhan, Deborah Lynn Proxmire, Edward Bruce Richter
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Patent number: 5713297Abstract: An adjustable sponson for a watercraft includes a coupling mechanism that allows the angular orientation of the sponson body relative to the hull of the watercraft to be varied by the operator of the watercraft without the use of any tools. The coupling mechanism also secures the sponson to the hull of the watercraft, maintaining the desired orientation of the sponson.Type: GrantFiled: September 5, 1996Date of Patent: February 3, 1998Assignee: Yamaha Hatsudoki Kabushiki KaishaInventors: Satoshi Tani, Toshiaki Ibata, Bruce Richter