Abstract: Described herein are compounds of Formula I, wherein the variables are defined herein, their use as HSD17B13 inhibitors and/or degraders, pharmaceutical compositions containing such compounds and their use to treat, for example, NAFLD and NASH.

Abstract: A method for concurrent execution of multiple protocols using a single radio of a wireless communication device is provided that includes receiving, in a radio command scheduler, a first radio command from a first protocol stack of a plurality of protocol states executing on the wireless communication device, determining a scheduling policy for the first radio command based on a current state of each protocol stack of the plurality of protocol stacks, and scheduling the first radio command in a radio command queue for the radio based on the scheduling policy, wherein the radio command scheduler uses the radio command queue to schedule radio commands received from the plurality of protocol stacks.

Abstract: The present application provides, in some aspects, methods of identifying a condensate of interest associated with a el disease. Also provided are methods of identifying a marker for identifying a condensate of interest associated with a disease. In other aspects, provided herein are methods of identifying a therapeutic agent useful for treating a disease via the identified condensate of interest.

Abstract: The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g.

Abstract: A ceramic waveguide includes: a doped metal oxide ceramic core layer; and at least one cladding layer comprising the metal oxide surrounding the core layer, such that the core layer includes an erbium dopant and at least one rare earth metal dopant being: lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, thulium, ytterbium, lutetium, scandium, or oxides thereof, or at least one non-rare earth metal dopant comprising zirconium or oxides thereof. Also included is a quantum memory including: at least one doped polycrystalline ceramic optical device with the ceramic waveguide and a method of fabricating the ceramic waveguide.

Abstract: A system for detecting Denial-of-Service (DoS) attacks on one or more user profiles collects a number of invalid sign-on attempts on the one or more user profiles during every time interval. The system determines a number of invalid sign-on attempts on every user profile since the start of the first time interval. The system detects a first DoS attack on a particular user profile if a first number of invalid sign-on attempts on the particular user profile exceeds a single-user profile. The system detects a second DoS attack on multiple user profiles during the first time interval if the increase in the total number of invalid sign-on attempts since the last time interval exceeds a scan-level threshold number. The system detects a third DoS attack on multiple user profiles if the total number of invalid sign-on attempts detected during combined time intervals exceeds a third threshold number.

Abstract: A method for concurrent execution of multiple protocols using a single radio of a wireless communication device is provided that includes receiving, in a radio command scheduler, a first radio command from a first protocol stack of a plurality of protocol states executing on the wireless communication device, determining a scheduling policy for the first radio command based on a current state of each protocol stack of the plurality of protocol stacks, and scheduling the first radio command in a radio command queue for the radio based on the scheduling policy, wherein the radio command scheduler uses the radio command queue to schedule radio commands received from the plurality of protocol stacks.

Abstract: An example system includes: a device coupled to a data line, the device configured to: send a first command on the data line, the first command including a first address; after sending the first command, read a first value on the data line, the first value including data from a first target device and a second target device; responsive to reading the first value, send a second command including the first address and data representing the first value on the data line; send a third command on the data line, the third command including the first address; after sending the third command, read a second value on the data line, the second value including data from the first target device and the second target device; responsive to reading the second value, send a fourth command on the data line, the fourth command including the first address.

Abstract: A method for concurrent execution of multiple protocols using a single radio of a wireless communication device is provided that includes receiving, in a radio command scheduler, a first radio command from a first protocol stack of a plurality of protocol states executing on the wireless communication device, determining a scheduling policy for the first radio command based on a current state of each protocol stack of the plurality of protocol stacks, and scheduling the first radio command in a radio command queue for the radio based on the scheduling policy, wherein the radio command scheduler uses the radio command queue to schedule radio commands received from the plurality of protocol stacks.

Abstract: A Flexible LED illumination device, according to the present invention, comprises a translucent positioning strip having a plurality of slots disposed at the center, a plurality of light modules mounted inside of the translucent positioning strip, a plurality of power conductors in communication to the plurality of light modules, a translucent housing covering the plurality of light modules, an elongated light diffuser tube disposed at the top of the translucent housing, and wherein said elongated light diffuser tube is configured to refract light from the plurality of light modules, a potting glue disposed at the bottom of the plurality of power conductors, and exposed power conductors extruding in between the plurality of light modules. The flexible LED illumination device is constructed with flexible material to allow bending to any shapes, and weatherproofing.

Abstract: A method for concurrent execution of multiple protocols using a single radio of a wireless communication device is provided that includes receiving, in a radio command scheduler, a first radio command from a first protocol stack of a plurality of protocol states executing on the wireless communication device, determining a scheduling policy for the first radio command based on a current state of each protocol stack of the plurality of protocol stacks, and scheduling the first radio command in a radio command queue for the radio based on the scheduling policy, wherein the radio command scheduler uses the radio command queue to schedule radio commands received from the plurality of protocol stacks.

Abstract: An expandable light bar system includes a plurality of light bar segments each having an elongated hollow body and a lighting unit. Each lighting unit includes a housing with a plurality of light emitting diodes that are electrically connected to either a subsequent lighting unit or a power source. The housing is secured onto a ridge that is located along the top surface of the elongated body. An expansion adaptor is positioned between two light bar segments and allows the overall length of the joined light bar segments to be adjustable. A spacer is positioned at the center of the adaptor and defines a minimum separation distance between the segments. A pair of endcaps are removably secured to one end of each of the light bar segments and are configured to engage an existing fluorescent high output socket within a light box to support placement of the joined segments.

Abstract: A method for concurrent execution of multiple protocols using a single radio of a wireless communication device is provided that includes receiving, in a radio command scheduler, a first radio command from a first protocol stack of a plurality of protocol states executing on the wireless communication device, determining a scheduling policy for the first radio command based on a current state of each protocol stack of the plurality of protocol stacks, and scheduling the first radio command in a radio command queue for the radio based on the scheduling policy, wherein the radio command scheduler uses the radio command queue to schedule radio commands received from the plurality of protocol stacks.

Abstract: A RGBW LED with integrated lens device includes two RGB LED's that are positioned adjacent to a single-color LED. A backer having a plurality of openings is positioned along the bottom of the LED's, and a plurality of cables are routed through the sides of the backer. A unitary clear lens body having a top wall, and a continuous sidewall extending downward therefrom to form an interior space. Three domes are formed along the top wall of the lens, and a lip is formed along the sidewall within the inside surface of the lens. The backer is positioned within the interior space of the lens along the lip, and each of the LED's are positioned within a single dome. Glue is poured through the plurality of openings to fill the interior space of the lens body to secure the device components in a watertight manner.

Abstract: A RGBW LED with integrated lens device includes two RGB LED's that are positioned adjacent to a single-color LED. A backer having a plurality of openings is positioned along the bottom of the LED's, and a plurality of cables are routed through the sides of the backer. A unitary clear lens body having a top wall, and a continuous sidewall extending downward therefrom to form an interior space. Three domes are formed along the top wall of the lens, and a lip is formed along the sidewall within the inside surface of the lens. The backer is positioned within the interior space of the lens along the lip, and each of the LED's are positioned within a single dome. Glue is poured through the plurality of openings to till the interior space of the lens body to secure the device components in a watertight manner.

Abstract: A method for concurrent execution of multiple protocols using a single radio of a wireless communication device is provided that includes receiving, in a radio command scheduler, a first radio command from a first protocol stack of a plurality of protocol states executing on the wireless communication device, determining a scheduling policy for the first radio command based on a current state of each protocol stack of the plurality of protocol stacks, and scheduling the first radio command in a radio command queue for the radio based on the scheduling policy, wherein the radio command scheduler uses the radio command queue to schedule radio commands received from the plurality of protocol stacks.

Abstract: An expandable light bar system includes a plurality of light bar segments each having an elongated hollow body and a lighting unit. Each lighting unit includes a housing with a plurality of light emitting diodes that are electrically connected to either a subsequent lighting unit or a power source. The housing is secured onto a ridge that is located along the top surface of the elongated body. An expansion adaptor is positioned between two light bar segments and allows the overall length of the joined light bar segments to be adjustable. A spacer is positioned at the center of the adaptor and defines a minimum separation distance between the segments. A pair of endcaps are removably secured to one end of each of the light bar segments and are configured to engage an existing fluorescent high output socket within a light box to support placement of the joined segments.

Abstract: A content recommendation system includes a content recommendation engine, a trender including a first trender interface to a social media platform and a second trender interface to a search engine, wherein the trender includes an ordered chain of term enhancers to enhance trending terms received via the first trender interface into enhanced terms. The search engine is adapted to receive the enhanced terms via the second trender interface and to form a search result set for the enhanced terms, and the search engine is coupled to provide the search result set to the content recommendation engine.

Abstract: A method for concurrent execution of multiple protocols using a single radio of a wireless communication device is provided that includes receiving, in a radio command scheduler, a first radio command from a first protocol stack of a plurality of protocol states executing on the wireless communication device, determining a scheduling policy for the first radio command based on a current state of each protocol stack of the plurality of protocol stacks, and scheduling the first radio command in a radio command queue for the radio based on the scheduling policy, wherein the radio command scheduler uses the radio command queue to schedule radio commands received from the plurality of protocol stacks.

Abstract: A machine system for operating a content recommendation system includes a monitor to detect and identify user actions on network connected digital devices, a first associator to relate the user actions to digital content, a timer operable to control a minimum time period filter on the user actions, a sequencer operable in conjunction with the timer, the minimum time period filter, and a combiner to transform the user actions into aggregate user actions. The content recommendation system is responsive to the aggregate user actions to evolve a computer-stored user profile according to the aggregate user actions.