Patents by Inventor Bruna Parma

Bruna Parma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090269586
    Abstract: The present invention relates to multimicrolamellar membranes of collagen of several types and structures (e.g. collagen type I, type II, type III, etc.), of only one type or two types in association, but more particularly of type I and type II collagen and/or of their mixture. The multimolecular arrangement is obtained by preparing the membrane in several steps involving the sequential addition of collagen gel layers. Membranes look thin, with a variable rough surface depending on the type of collagen used. Such membranes show a parallel horizontal lamellar microstructure and they can be soaked with different fluids, act as three-dimensional scaffold for cultured cells and are apt to be infiltrated and colonized by cells in vivo, therefore working as support suitable for direct, guided tissue regeneration. Moreover, the present invention relates to the preparation of said membranes from collagen gels and to the optimization of the preparation of collagen gel from tissues.
    Type: Application
    Filed: April 3, 2007
    Publication date: October 29, 2009
    Applicant: Opocrin S.p.A.
    Inventors: Bruna Parma, Antonio Gigante
  • Publication number: 20090149423
    Abstract: The present invention relates to the use of heparin oligosaccharides having a molecular weight?5050 Da and an anti-factor Xa activity?80 IU/mg, or their sodium salts, for preparing a medicament for the prevention and treatment of osteoporosis and associated pathologies and for preparing a medicament effective for the prevention and treatment of cerebral ischemia and pathologies related thereto whose treatment necessitates drugs able to cross the blood-brain barrier.
    Type: Application
    Filed: October 27, 2005
    Publication date: June 11, 2009
    Applicant: OPOCRIN S.P.A.
    Inventors: Pietro Bianchini, Giuseppe Mascellani, Bruna Parma
  • Publication number: 20040013712
    Abstract: The present invention concerns doublke sided colagen membranes, one of which is porous, suitable for the adhesion and/or growth of cells, and a smooth one characterized in that the collagen fibres are arranged at macromolecular level. Moreover, the process for the preparation of such membranes is described and their use as supports for the adhesion and/or growth of mammalian cells in vitro and as matrices for tissue reconstruction.
    Type: Application
    Filed: August 4, 2003
    Publication date: January 22, 2004
    Inventor: Bruna Parma