Abstract: A method is described for detecting the presence of at least one trichophyton involved in a mycosis of the skin and skin apendages. The method can include a step of determining the presence, in a sample of skin or skin appendage from a human being or an animal that may be infected with a trichophyton, of at least one protease selected from dipeptidyl peptidase V, subtilisin-like protease 6, subtilisin-like protease 7, leucine aminopeptidase 1 and leucine aminopeptidase 2. Also described, is a monoclonal antibody directed against dipeptidyl peptidase V, subtilisin-like protease 6 or leucine aminopeptidase 2 or a fragment of this antibody capable of binding respectively to dipeptidyl peptidase V, subtilisin-like protease 6 or leucine aminopeptidase 2, and a kit including this antibody.

Abstract: The invention provides a cosmetic or pharmaceutical composition comprising, in a physiologically acceptable medium, at least one purified natural or synthetic polypeptide wherein the peptide sequence is represented wholly or partly by at least one sequence selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 16, SEQ ID NO: 25 and SEQ ID NO: 27 and their homologs.

Abstract: A non-invasive method for collecting biological data useful for establishing a diagnosis or a prognosis of a particular cutaneous pathology in a patient, includes: a) obtaining a skin sample containing biological material by applying a layer of adhesive on the skin of such patient, and then removing the adhesive containing such skin sample/biological material, and b) conducting mass spectrometry and detecting, in the sample, at least one protein whose presence, absence, or variation in amount or concentration relative to a standard value is associated with the presence, the development or the absence of a particular cutaneous pathology; the subject methodology is particularly suitable for establishing a diagnosis or a prognosis of psoriasis.

Abstract: The invention provides a cosmetic or pharmaceutical composition comprising, in a physiologically acceptable medium, at least one purified natural or synthetic polypeptide wherein the peptide sequence is represented wholly or partly by at least one sequence selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 16, SEQ ID NO: 25 and SEQ ID NO: 27 and their homologs.

Abstract: The invention provides a cosmetic or pharmaceutical composition comprising, in a physiologically acceptable medium, at least one purified natural or synthetic polypeptide wherein the peptide sequence is represented wholly or partly by at least one sequence selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 16, SEQ ID NO: 25 and SEQ ID NO: 27 and their homologs.

Abstract: The invention provides a cosmetic or pharmaceutical composition comprising, in a physiologically acceptable medium, at least one purified natural or synthetic polypeptide wherein the peptide sequence is represented wholly or partly by at least one sequence selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, SEQ ID NO: 9, SEQ ID NO: 16, SEQ ID NO: 25 and SEQ ID NO: 27 and their homologs.

Abstract: The invention concerns an isolated polypeptide, of the family of calcium-fixing proteins, a mixture of polypeptides derived from proteolysis of the isolated polypeptide, compositions containing them, the uses of said polypeptide and a cosmetic treatment method for dry skin, hyperkeratosis, parakeratosis, psoriasis, ichthyosis, and neoplasia. The invention also concerns a deoxyribonucleic acid sequence coding for said polypeptide and the uses of said deoxyribonucleic sequence.

Abstract: The present invention concerns compositions containing carbohydrate derivatives for enhancing the skin barrier function. The invention further concerns a cosmetic treatment method for enhancing the skin barrier function by applying on the skin compositions comprising carbohydrate derivatives.

Abstract: The invention concerns an isolated polypeptide, of the family of calcium-fixing proteins, a mixture of polypeptides derived from proteolysis of the isolated polypeptide, compositions containing them, the uses of said polypeptide and a cosmetic treatment method for dry skin, hyperkeratosis, parakeratosis, psoriasis, ichthyosis, and neoplasia. The invention also concerns a deoxyribonucleic acid sequence coding for said polypeptide and the uses of said deoxyribonucleic sequence.

Abstract: Hydrolase polypeptides having amidase activity and products capable of modulating the activity thereof are well suited for the treatment of, inter alia, dry skins and/or the signs of skin aging and/or for combating skin desquamation.

Abstract: The invention concerns an isolated polypeptide, of the family of calcium-fixing proteins, a mixture of polypeptides derived from proteolysis of the isolated polypeptide, compositions containing them, the uses of said polypeptide and a cosmetic treatment method for dry skin, hyperkeratosis, parakeratosis, psoriasis, ichthyosis, neoplasia. The invention also concerns a deoxyribonucleic acid sequence coding for said polypeptide and the uses of said deoxyribonucleic sequence.

Abstract: The present invention concerns compositions comprising at least a glycosidase but not a protease to promote scaling. The invention further concerns the use of the compositions for treating dry skin or for preventing or treating skin aging.

Abstract: The present invention concerns compositions containing carbohydrate derivatives for enhancing the skin barrier function. The invention further concerns a cosmetic treatment method for enhancing the skin barrier function by applying on the skin compositions comprising carbohydrate derivatives.

Abstract: The present invention concerns compositions suitable for topical application, comprising glucosylated hydroxystilbenes. It also concerns a method for slowly releasing hydroxystilbenes into the stratum corneum, by applying a composition comprising glucosylated hydroxystilbenes as a precursor. Finally, it concerns the use of glucosylated hydroxystilbenes to combat signs of cutaneous and hair follicle ageing, to improve the radiance of the skin, to smooth the skin of the face, to treat or prevent wrinkles and fine lines in the skin or to stimulate the epidermal renewal process.