Patents by Inventor Bruno Miroux

Bruno Miroux has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fusion proteins comprising coiled-coil structures derived of bovine IF1 ATPase inhibitor protein
    Patent number: 6498020
    Abstract: The present invention relates to a fusion protein comprising a first amino acid sequence comprising the sequence of the C-terminal 40 amino acids of bovine IF1 ATPase inhibitor protein, and a second amino acid sequence not naturally associated with the first region. The invention further relates to methods for preparing an immunoglobulin comprising immunizing an animal with the fusion protein and recovering immunoglobulin specific for a region of the fusion protein.
    Type: Grant
    Filed: December 27, 1999
    Date of Patent: December 24, 2002
    Assignee: Medical Research Council
    Inventors: John Walker, Bruno Miroux
  • Over-expression of proteins
    Patent number: 6361966
    Abstract: The invention describes a method for selecting host cell mutants which are resistant to expression system toxicity, comprising the steps of growing an expression system comprising host cells transformed with an expression vector, inducing the expression system such that a toxic effect is observed, and selecting viable cells in which the expression vector continues to function. Cells thus obtained are useful for the expression of polypeptide gene products in microorganisms.
    Type: Grant
    Filed: September 15, 1999
    Date of Patent: March 26, 2002
    Assignee: Medical Research Council
    Inventors: John Ernest Walker, Bruno Miroux