Patents by Inventor Bruno Rene Andre

Bruno Rene Andre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL METHOD
    Publication number: 20140315277
    Abstract: The present invention relates to a method for degrading host cell nucleic acids associated with a virus or a viral antigen thereof produced by cell culture, the method comprising at least two steps of nucleic acids degradation with a compound selected from i) an endonuclease and ii) a DNA alkylating agent.
    Type: Application
    Filed: February 20, 2014
    Publication date: October 23, 2014
    Applicant: GlaxoSmithKline Biologicals s. a.
    Inventors: Bruno Rene ANDRE, Benoit Paul Suzanne Champluvier, Benedicte Van Der Hayden
  • NOVEL METHOD
    Publication number: 20130039943
    Abstract: A method for inactivating an orthomyxovirus propagated in cell culture and/or inactivating contaminating adventitious agents, comprising at least the following steps: (a) treating an orthomyxovirus-containing fluid with an alkykating agent, and (b) irradiating the orthomyxovirus-containing fluid with UV light.
    Type: Application
    Filed: April 28, 2011
    Publication date: February 14, 2013
    Inventors: Bruno Rene Andre, Benoit Paul Suzanne Champluvier
  • METHOD FOR PRODUCING VIRUS FROM CELL CULTURE INVOLVING HOMOGENIZATION
    Publication number: 20120058145
    Abstract: A method of purifying a virus, or a viral antigen thereof, from a culture of infected cells comprising at least the steps of: (a) collecting the virus-containing cell culture medium, and (b) purifying the virus, wherein at least one homogenization step is implemented during the purification to obtain a virus homogenate.
    Type: Application
    Filed: May 6, 2010
    Publication date: March 8, 2012
    Inventors: Bruno Rene Andre, Benoit Paul Suzanne Champluvier
  • NOVEL METHOD
    Publication number: 20110293660
    Abstract: The present invention relates to a method for purifying a virus, or a viral antigen thereof, comprising at least the following steps: a) obtaining a fluid comprising the virus, or a viral antigen thereof, and b) purifying the fluid by at least one density gradient ultracentrifugation step, wherein the ratio of the amount of virus, or viral antigen thereof, present in the fluid over the density gradient volume is less than 1, less than 0.8, less than 0.6 and less than 0.4.
    Type: Application
    Filed: February 4, 2010
    Publication date: December 1, 2011
    Inventors: Bruno Rene Andre, Benoit Paul Suzanne Champluvier
  • NOVEL METHOD
    Publication number: 20110217330
    Abstract: The present invention relates to a method for degrading host cell nucleic acids associated with a virus or a viral antigen thereof produced by cell culture, the method comprising at least two steps of nucleic acids degradation with a compound selected from i) an endonuclease and ii) a DNA alkylating agent.
    Type: Application
    Filed: November 3, 2009
    Publication date: September 8, 2011
    Inventors: Bruno Rene Andre, Benoit Paul Suzanne Champluvier, Bénédicte Van Der Heyden