Abstract: Antibodies that bind SARS-CoV spike protein, SARS-CoV-2 spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2.

Abstract: The present disclosure provides ammonium compounds, e.g., compounds according to Formula I as set forth herein, which are useful as antimicrobial agents. Methods for the treatment of bacterial infections and associated conditions, e.g., gastrointestinal conditions, are also described, as well as methods for altering the microbiome of subjects such as humans.

Abstract: Systems, methods, and computer-readable media are described for compact radar systems. In some examples, a compact radar system can include a first set of transmit antennas, a second set of receive antennas, one or more processors, and at least one computer-readable storage medium storing computer-executable instructions which, when executed by the one or more processors, cause the radar system to coordinate digital beam steering of the first set of transmit antennas and the second set of receive antennas, and coordinate digital beam forming with one or more of the second set of receive antennas to detect one or more objects within a distance of the radar system.

Abstract: The present disclosure provides ammonium compounds, e.g., compounds according to Formula I as set forth herein, which are useful as antimicrobial agents. Methods for the treatment of bacterial infections and associated conditions, e.g., gastrointestinal conditions, are also described, as well as methods for altering the microbiome of subjects such as humans.

Abstract: Compositions and methods for isolating biologically active polypeptides (e.g., bacterial pro-growth polypeptides) are provided. In some aspects, bacterial cell populations are provided that express a surface-displayed library of candidate polypeptide sequences under the control of an inducible promoter.

Abstract: In an electronic device, plural circuit boards are plugged into respective connectors, or sockets, in a common backplane circuit board. The backplane maintains the flat circuit boards in fixed relation to one another. Each circuit board is provided with a respective optical transmitter and/or receiver to allow for the transmission of (typically digital) information via a high speed carrier in a light beam through unobstructed free space between the circuit boards. The circuit boards may also be provided with optical splitters and/or combiners as well as apertures to permit light signals to pass through the board's substrate to allow for communication between plural circuit boards. The circuit boards may further include small lenses and/or opaque elements to provide an optical path having selected physical characteristics.

Abstract: The invention relates to a process for the preparation of certain quinoline derivatives, in particular, 8-[(4-amino-1-methylbutyl)amino]-2,6-dimethoxy-4-methyl-5-(3-trifluoromethylphenoxy)quinoline succinate.

Abstract: An accurate position of a mobile receiver is determined using a received positional signal having relatively low and high frequency noise components corrupting the positional accuracy of the positional signal. A low frequency error associated with a detected turn of the mobile receiver is derived and applied as a low frequency correction factor to positions of the receiver derived after the turn is detected. Resulting corrected positions are applied along with associated high frequency correction factors representative of the high frequency noise component to a predictive filter to derive predicted positions substantially free of the low and high frequency noise components.

Abstract: The present invention relates generally to automatic vehicle navigational systems, and more particularly, to an automatic vehicle routing and recommendation system. Even more particularly, the present invention is directed to a system for choosing one of a plurality of potential vehicles in a fleet for routing the fleet vehicle over the shortest distance and/or time from a current location to a target point such as a fire or a passenger for a taxicab.

Abstract: The present invention relates generally to automatic vehicle navigational systems, and more particularly, to an automatic vehicle routing and recommendation system. Even more particularly, the present invention is directed to a system for choosing one of a plurality of potential vehicles in a fleet for routing the fleet vehicle over the shortest distance and/or time from a current location to a target point such as a fire or a passenger for a taxicab.

Abstract: An accurate position of a mobile receiver is determined using a received positional signal having relatively low and high frequency noise components corrupting the positional accuracy of the positional signal. A low frequency error associated with a detected turn of the mobile receiver is derived and applied as a low frequency correction factor to positions of the receiver derived after the turn is detected. Resulting corrected positions are applied along with associated high frequency correction factors representative of the high frequency noise component to a predictive filter to derive predicted positions substantially free of the low and high frequency noise components.

Abstract: Disclosed is a method for displaying a topology having topological features on a display. The method includes dividing the topological region into tessellations. An object-based database is accessed which comprises geometrical objects representing the topological features with each geometrical object associated with a particular tessellation. The geometrical objects are one of a polygon object, a polyline object and a point object representing the topological features. A tessellation is selected to be displayed. The geometrical objects are fetched which are associated with the tessellations to be displayed. The fetched geometrical objects are drawn on the display.

Abstract: The present invention is a GIS system in which topological information is classified as geometrical objects and uses a region identifier and a geometry attribute to reconstruct each topological feature. The present invention starts from the geometrical objects representing topological features. Each geometrical object has an entry including a region identifier attribute and a geometry attribute defining the geometry of a complete representation of the feature. These geometrical objects are complete in that an entry of the object attribute includes a record for a geometry attribute defining the complete geometry of a complete representation of a topological feature. These complete geometrical objects need not inherit attributes from other objects. The objects are classified as either a polygon object, polyline object, point object or raster object and stored in a respective object-based database.

Abstract: A method and system are disclosed for providing a more accurate position of a mobile receiver even though a signal received by the mobile receiver indicating the position of the mobile receiver is inaccurate. The received signal is used as an estimated indication of the position of the mobile receiver. A database comprises geometrical objects representing navigable routes. The geometrical objects include a geometry attribute defining the geometry of a complete representation of the navigable route. A geometrical object representing a navigable route is determined where the mobile receiver is probably located. The estimated position of the mobile receiver can then be compared against the geometry of the navigable route and against the previous positions in which the mobile receiver was located. The estimated position of the mobile receiver can be adjusted if necessary to provide a more probable position of the mobile receiver.

Abstract: A system and method for defining a process structure for performing a task. The system comprises a computer, having a data storage memory, a keyboard for inputting data and a screen. A user inputs a first process definition which comprises a verb word and an object word defining the task for which a structure is to be created. The user is then able to define subsequent process definitions which are a predicted consequence of executing the first process definition or a predicted constituent step in executing the first process definition. By analyzing each process definition at each stage a complete process structure for performing the task can be built up and refined. The user is also able to specify particular object words falling within the meaning of the object word of a particular process definition which can be called up in tabular form on the screen, overwriting the display of process definitions in the process structure.