Abstract: The present disclosure provides aseptic vial piercing and sterilization systems, and methods of assembling, using and sterilizing same. The systems and methods utilize a pre-sterilized primary container including a first end, a first cavity, a second end with an opening in communication with the first cavity, a septum at least partially sealing the opening, and a product within the first cavity. The systems and methods include an injection assembly including a first end portion of a hollow flowpath forming member. The injection assembly and the primary container may be assembled in a non-sterile environment to form a second cavity extending about the first end portion of the flowpath forming member and to the primary container. The second cavity may then be selectively sterilized in a non-deleterious manner to the product to allow the first end portion to aseptically pierce the septum to extend into the first cavity.

Abstract: The present disclosure provides aseptic vial piercing and sterilization systems, and methods of assembling, using and sterilizing same. The systems and methods utilize a pre-sterilized primary container including a first end, a first cavity, a second end with an opening in communication with the first cavity, a septum at least partially sealing the opening, and a product within the first cavity. The systems and methods include an injection assembly including a first end portion of a hollow flowpath forming member. The injection assembly and the primary container may be assembled in a non-sterile environment to form a second cavity extending about the first end portion of the flowpath forming member and to the primary container. The second cavity may then be selectively sterilized in a non-deleterious manner to the product to allow the first end portion to aseptically pierce the septum to extend into the first cavity.

Abstract: The present disclosure provides aseptic vial piercing and sterilization systems, and methods of assembling, using and sterilizing same. The systems and methods utilize a pre-sterilized primary container including a first end, a first cavity, a second end with an opening in communication with the first cavity, a septum at least partially sealing the opening, and a product within the first cavity. The systems and methods include an injection assembly including a first end portion of a hollow flowpath forming member. The injection assembly and the primary container may be assembled in a non-sterile environment to form a second cavity extending about the first end portion of the flowpath forming member and to the primary container. The second cavity may then be selectively sterilized in a non-deleterious manner to the product to allow the first end portion to aseptically pierce the septum to extend into the first cavity.

Abstract: Fuel feed systems capable of providing substantially consistent flow of fuel to a fuel cell and also capable of tolerating varying pressures from a reservoir (also referred to as fuel supply or fuel cell cartridge) and the fuel cell while maintaining substantially consistent control flow to the fuel cell are disclosed.

Abstract: Fuel feed systems capable of providing substantially consistent flow of fuel to a fuel cell and also capable of tolerating varying pressures from a reservoir (also referred to as fuel supply or fuel cell cartridge) and the fuel cell while maintaining substantially consistent control flow to the fuel cell are disclosed.

Abstract: Embodiments of a valve are disclosed that allow for the control and adjustment of a fluid flow between a valve inlet port and a valve output port as a function of the pressure at the valve inlet port, a pressure at a first pressure input port, and a reference pressure.

Abstract: A system-to-reservoir connector is disclosed in which a system-side-sub-connector and a reservoir-side-sub-connector provide for a fluid connection that is resilient to external forces, is substantially leak-proof upon insertion and retraction, and is orientation independent.

Abstract: Fuel feed systems capable of providing substantially consistent flow of fuel to a fuel cell and also capable of tolerating varying pressures from a reservoir (also referred to as fuel supply or fuel cell cartridge) and the fuel cell while maintaining substantially consistent control flow to the fuel cell are disclosed.

Abstract: A system and method for managing gas bubbles in a liquid flow system are described. In particular, according to the system and method, novel techniques reduce a volume of cavities in the liquid flow system and limit a cross-sectional area of the liquid flow system to a maximum cross-sectional area of tolerably sized bubbles. In this manner, by reducing the cavity volumes and limiting cross-sectional areas, the formation of intolerably sized bubbles and the aggregation of tolerably sized bubbles into intolerably sized bubbles are each substantially prevented. Also, bubbles may be removed from the system to reduce the quantity of bubbles that are to be managed.