Abstract: Transdermal, oral and intravenous formulations of 2,3-dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone (coenzyme Q10), containing an effective amount of pulmonary surfactant, also in combination with liposomes, in addition to usual excipients.

Abstract: Lung surfactant compositions are provided which can form a swelling phase when dispersed in a medium containing electrolytes. Hereby, a more active spreading of the lung surfactant into the alveoli can be obtained after administration to the lungs. Further provided are a pharmaceutical composition and a pharmaceutical kit comprising a lung surfactant composition as well as to a method for the treatment, prevention and/or diagnosis of respiratory distress syndrome or other pulmonary diseases that are associated with a deficiency of a lung surfactant.

Abstract: Transdermal, oral and intravenous formulations of 2,3-dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone (coenzyme Q10), containing an effective amount of pulmonary surfactant, also in combination with liposomes, in addition to usual excipients.

Abstract: Lung surfactant compositions are provided which can form a swelling phase when dispersed in a medium containing electrolytes. Hereby, a more active spreading of the lung surfactant into the alveoli can be obtained after administration to the lungs. Further provided are a pharmaceutical composition and a pharmaceutical kit comprising a lung surfactant composition as well as to a method for the treatment, prevention and/or diagnosis of respiratory distress syndrome or other pulmonary diseases that are associated with a deficiency of a lung surfactant.

Abstract: A pulmonary surfactant formulation for instillation and oral application, containing at least 0.1% by weight of 2,3 -dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone in addition to an effective amount of pulmonary surfactant and usual excipients.

Abstract: 2,3-Dimethoxy-5-methyl-6-decaprenyl-1,4-benzoquinone can be used for the topical and oral treatment of diseases of the skin and the mucosae of the mouth, the stomach, the bowels, the vagina and the lung.

Abstract: A method and an apparatus for determining when a partially or completely collapsed lung has been opened are based on the fact that in the course of opening an alveolus by supplying a gas pressure, the alveolus will generate a crackle sound. By listening to the crackle sounds via microphones, an apparatus can determine when the lung is completely open. The apparatus has a filter for filtering out the relevant frequencies for the crackle sounds and a determination unit for identifying the crackles and for determining when the lung is open based on the filtered out sounds.

Abstract: A process for the production of aromatic amines by catalylic hydrogenation.

Abstract: In an artificial ventilation system and a method for controlling the artificial ventilation system for obtaining an optimized artificial ventilation of a lung system of a patient, optimal artificial ventilation is obtained when the blood system of the patient is maximally oxygenated and, at the same time, the negative influence on the cardio-pulmonary system is minimized. The ventilation system has a gas delivery unit for delivering controllable inspiration pulses to a patient, a monitoring unit for measuring at least one parameter related to the function of the lung system, such as a blood gas analyser, and a control unit for determining an optimal peak inspiratory pressure and pressure amplitude for the inspiration pulse based on the measured blood gas parameter.

Abstract: An arrangement for determining an opening pressure of a lung has a regulating unit which can deliver inspiration pulses to a patient's lung system, a blood gas analyzer for measuring the partial pressure of oxygen in the blood of the patient's circulatory system, and a control unit for determining an opening pressure based on the measured P.sub.a O.sub.2. When the measured P.sub.a O.sub.2 exceeds a predetermined threshold, the lung have opened sufficiently and a pressure value is correlated to the measured P.sub.a O.sub.2 and defined as the opening pressure.

Abstract: A breathing apparatus for supplying a supportive inspiration pulse in response to a sensed inhalation effort of a subject connected to the apparatus has a supportive response controlled so that the amplitude of the inspiration pulse displays an inverse relationship to the magnitude of the sensed inhalation effort.

Abstract: In an apparatus and method for determining an optimal opening pressure of a lung system a regulating unit delivers an inspiration pulse having an end pressure which is higher than the start pressure to the lung system. During the delivery of this inspiration pulse respiratory gas flow and pressure are measured by a measuring unit having a flow meter and a pressure gauge. The measured values are supplied to a control unit, in which measured flow and pressure are correlated and inflection points or regions in the flow-pressure-relation are identified. The highest pressure value related to an inflection point or region is defined as an interim opening pressure. By applying several different inspiration pulses, several interim opening pressures can be determined.

Abstract: Supported catalysts containing palladium on a support material are improved by added bases which remain on the material. These supported catalysts are useful for hydrogenating optionally substituted phenols to give the corresponding cyclohexanols as the predominant product.

Abstract: The present invention relates to new benzylidenemalonic or vinylogous benzylidenemalonic acid polyesters containing structural units of the formula (I) ##STR1## their preparation and their use for the UV stabilization of thermoplastics, preferably thermoplastic, aromatic polycarbonates, thermoplastic, aromatic polyesters or thermoplastic polymethylmethacrylates.

Abstract: Self-extinguishing thermoplastic polyamide moulding compositions containing barbituric acid and/or reaction products thereof as flameproofing agent.

Abstract: A process for the hydrogenation of nitrobenzene to aniline is described wherein the nitrobenzene is contacted with hydrogen in the presence of a multi-component supported catalyst containing 1 to 20 grams of noble metal per liter of support and 1 to 20 grams per liter of support of one or more transition metal of the Groups IVa, Va, or VIa of the Periodic Table. The catalyst can contain 1 to 20 grams per liter of support of a further transition group element or of a member of the main group. The catalyst is one which has been prepared by a process involving pretreatment of the support with a base prior to impregnation with the catalytically active substances, followed by drying to a residual moisture content of less than 10 percent of the maximum absorbency of the support.

Abstract: Object of the invention are UV absorbents for numerous polymers which are distinguished by their comparative lack of self-color, high light absorption and good compatibility with the polymers as well as with other additives.

Abstract: Piperidine derivatives of formula ##STR1## can be prepared by reacting 4-amino-piperidine with for example enolic ethers. The compounds obtained may be used as stabilizers.

Abstract: Homopolymers and copolymers based on alkenoyloxybenzylidene-malonic esters of the formula ##SPC1##WhereR.sup.1 is hydrogen or C.sub.1 to C.sub.4 -alkyl;R.sup.2 is C.sub.1 to C.sub.12 -alkyl or cycloalkyl andR.sup.3 is hydrogen, C.sub.1 to C.sub.8 -alkyl, C.sub.1 to C.sub.8 -alkoxy or halogen, and plastics, i.e., polycarbonates, stabilized therewith.