Patents by Inventor Byron T. Ballou

Byron T. Ballou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for selection of primate tumor-associated antigens suitable as in vivo targets for antibodies
    Patent number: 5049373
    Abstract: The present invention is a process for the selection of antigens which are suitable targets for in vivo antibody localization in human tumors or other altered (or diseased) tissue. The process provides a simplified and rapid technique for discovering useful in vivo targets for antibodies and is useful in cancer detection and therapy in humans or other primates, whether or not the antigens are specific to tumors. More specifically, the invention relates to a process for the selection of antigens suitable as targets for antibodies which localize in a tumor in vivo in which antibodies are first prepared distinguishable from those present in the animal in which biofiltration is to occur and that bind to antigens present in the tumor to be targeted. These antibodies are then injected into a non-tumor-bearing primate, into a tumor-bearing animal, and into a non-tumor bearing animal of the same species as the tumor-bearing animal to permit biofiltration of the antibodies.
    Type: Grant
    Filed: July 13, 1990
    Date of Patent: September 17, 1991
    Assignee: University of Pittsburgh
    Inventor: Byron T. Ballou
  • Novel method for selection of primate tumor-associated antigens suitable as in vivo targets for antibodies
    Patent number: 4978520
    Abstract: The present invention is a process for the selection of antigens which are suitable targets for in vivo antibody localization in human tumors or other altered (or diseased) tissue. The process provides a simplified and rapid technique for discovering useful in vivo targets for antibodies and is useful in cancer detection and therapy in humans or other primates, whether or not the antigens are specific to tumors. More specifically, the invention relates to a process for the selection of antigens suitable as targets for antibodies which localize in a tumor in vivo in which antibodies are first prepared distinguishable from those present in the animal in which biofiltration is to occur and that bind to antigens present in the tumor to be targeted. These antibodies are then injected into a non-tumor-bearing primate, into a tumor-bearing animal, and into a non-tumor bearing animal of the same species as the tumor-bearing animal to permit biofiltration of the antibodies.
    Type: Grant
    Filed: January 11, 1989
    Date of Patent: December 18, 1990
    Assignee: University of Pittsburgh
    Inventor: Byron T. Ballou
  • Method for selection of antigens suitable as in vivo targets for antibodies
    Patent number: 4798719
    Abstract: The present invention is a process for the selection of antigens which are suitable targets for in vivo antibody localization in tumors or other altered (or diseased) tissue. The process provides a simplified and rapid technique for discovering useful in vivo targets for antibodies and is useful in cancer detection and therapy in humans or animals, whether or not the antigens are specific to tumors.
    Type: Grant
    Filed: September 11, 1986
    Date of Patent: January 17, 1989
    Assignee: University of Pittsburgh
    Inventor: Byron T. Ballou