Patents by Inventor Byung-Hwa Hyun

Byung-Hwa Hyun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6562866
    Abstract: 0A method for treating or preventing an elevated blood lipid level-related disease in a mammal, which comprises administering thereto an effective amount of rutin, quercetin or a mixture thereof.
    Type: Grant
    Filed: August 28, 2000
    Date of Patent: May 13, 2003
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Ki-Hwan Bae, Yong-Bok Park, Myung-Sook Choi, Surk-Sik Moon, Yong-Kook Kwon, Eun-Sook Lee, Byung-Hwa Hyun, Yang-Kyu Choi, Chul-Ho Lee, Sae-Bom Lee, Young-Bae Park, Hyo-Soo Kim
  • Patent number: 6509372
    Abstract: A method for treating or preventing an elevated blood lipid level-related disease in a mammal, which comprises administering thereto an effective amount of rutin, quercetin or a mixture thereof.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: January 21, 2003
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Ki-Hwan Bae, Yong-Bok Park, Myung-Sook Choi, Surk-Sik Moon, Yong-Kook Kwon, Eun-Sook Lee, Byung-Hwa Hyun, Yang-Kyu Choi, Chul-Ho Lee, Sae-Bom Lee, Young-Bae Park, Hyo-Soo Kim
  • Patent number: 6465019
    Abstract: The present invention relates to a spice composition comprising 1 to 30 % by weight of garlic, 10 to 50% by weight of onion, 0.2 to 10% by weight of ginger, 5 to 40% by weight of jujube, and 10 to 50% by weight of citrus peel or an extract thereof or 1 to 20% by weight of naringin or hesperidin.
    Type: Grant
    Filed: October 5, 2000
    Date of Patent: October 15, 2002
    Assignee: Korea Institute of Science and Technology
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Ki-Hwan Bae, Yong-Bok Park, Myung-Sook Choi, Yong-Kook Kwon, Byung-Hwa Hyun, Yang-Kyu Choi, Chul-Ho Lee, Surk-Sik Moon
  • Patent number: 6455577
    Abstract: A compound of formula (I) treating or preventing an elevated blood lipid level-related disease and inhibiting the activities of acyl-CoA:cholesterol-O-acyltransferase(ACAT) and 3-hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase: wherein, R1 is R5 R6CO group; R2 is H or R6CO group; R3 is H, CH3, R5 or R6CO group; R4 is H, OH, OR5 or R6COO group; R5 is a C2-5 alkyl group substituted with a phenyl group optionally having one or more substituents selected from the group consisting of C1-3 alkyl, OH, Cl and NO2; a C1-5 alkyl group substituted with a naphthyl group optionally having one or more substituents selected from the group consisting of C1-3 alkyl, OH, Cl and NO2; a C10-18 alkyl; or a C10-18 alkenyl group; and R6 is a C10-18 alkenyl group; or an aryl group optionally having one or more substituents selected from the group consisting of C1-3 alkyl, OH, Cl or NO2.
    Type: Grant
    Filed: January 24, 2001
    Date of Patent: September 24, 2002
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Sang-Ku Lee, Ju-Ryong Kim, Surk-Sik Moon, Myung-Sook Choi, Byung-Hwa Hyun, Chul-Ho Lee, Yang-Kyu Choi
  • Patent number: 6313171
    Abstract: A method for treating or preventing an elevated blood lipid level-related disease such as hyperlipidemia, arteriosclerosis, angina pectoris, stroke and hepatic diseases in a mammal, which comprises administering thereto an effective amount of a cinnamic acid derivative of formula Ia or Ib, or a pharmaceutically acceptable salt thereof: wherein, R1, R2, R3, R4 and R5 are independently H, OH or C1-4 alkoxy; and R6 is H, C1-4 alkyl group, or C5-7 cycloalkyl group having one or more substituents selected from the group consisting of OH, alkoxy and carboxy groups.
    Type: Grant
    Filed: September 15, 1999
    Date of Patent: November 6, 2001
    Assignee: Korea Research Institute of Bioscience & Biotechnology
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Ki-Hwan Bae, Yong-Bok Park, Myung-Sook Choi, Surk-Sik Moon, Yong-Kook Kwon, Eun-Sook Lee, Byung-Hwa Hyun, Yang-Kyu Choi, Chul-Ho Lee, Sae-Bom Lee, Young-Bae Park, Hyo-Soo Kim
  • Publication number: 20010014357
    Abstract: Methods for inhibiting the activity of acyl CoA-cholesterol-o-acyltransferase, inhibiting the accumulation of macrophage-lipid complex on the arterial endothelium, and preventing or treating hepatic diseases in a mammal comprise administering a citrus peel extract thereto.
    Type: Application
    Filed: February 12, 2001
    Publication date: August 16, 2001
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Ki-Hwan Bae, Yong-Bok Park, Myung-Sook Choi, Surk-Sik Moon, Yong-Kook Kwon, Eun-Sook Lee, Byung-Hwa Hyun, Yang-Kyu Choi, Chul-Ho Lee, Jun-Sung Lee, Kwang-Hee Son, Byoung-Mog Kwon, Young-Kook Kim, Doil Choi, Sung-Uk Kim, Ingyu Hwang, Jung-Ah Ahn, Young-Bae Park, Hyo-Soo Kim, Seong-Choon Choe
  • Publication number: 20010014669
    Abstract: A method for treating or preventing an elevated blood lipid level-related disease in a mammal, which comprises administering thereto an effective amount of rutin, quercetin or a mixture thereof.
    Type: Application
    Filed: March 13, 2001
    Publication date: August 16, 2001
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Ki-Hwan Bae, Yong-Bok Park, Myung-Sook Choi, Surk-Sik Moon, Yong-Kook Kwon, Eun-Sook Lee, Byung-Hwa Hyun, Yang-Kyu Choi, Chul-Ho Lee, Sae-Bom Lee, Young-Bae Park, Hyo-Soo Kim
  • Publication number: 20010006978
    Abstract: A compound of formula (I) treating or preventing an elevated blood lipid level-related disease and inhibiting the activities of acyl-CoA:cholesterol-O-acyltransferase(ACAT) and 3-hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase: 1
    Type: Application
    Filed: January 24, 2001
    Publication date: July 5, 2001
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Sang-Ku Lee, Ju-Ryong Kim, Surk-Sik Moon, Myung-Sook Choi, Byung-Hwa Hyun, Chul-Ho Lee, Yang-Kyu Choi
  • Publication number: 20010002264
    Abstract: Method for inhibiting the formation of fatty streak on the arterial endothelium in a mammal comprise administering a citrus peel extract or citrus peel powder thereto.
    Type: Application
    Filed: December 28, 2000
    Publication date: May 31, 2001
    Applicant: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Ki-Hwan Bae, Yong-Bok Park, Myung-Sook Choi, Surk-Sik Moon, Yong-Kook Kwon, Eun-Sook Lee, Byung-Hwa Hyun, Yang-Kyu Choi, Chul-Ho Lee, Jun-Sung Lee, Kwang-Hee Son, Byoung-Mog Kwon, Young-Kook Kim, Doil Choi, Sung-Uk Kim, Ingyu Hwang, Jung-Ah Ahn, Young-Bae Park, Hyo-Soo Kim, Seong-Choon Choe
  • Patent number: 6165984
    Abstract: Methods for inhibiting the activity of acyl CoA-cholesterol-o-acyltransferase, inhibiting the accumulation of macrophage-lipid complex on the arterial endothelium, and preventing or treating hepatic diseases in a mammal comprise administering naringin or naringenin thereto.
    Type: Grant
    Filed: October 28, 1998
    Date of Patent: December 26, 2000
    Assignee: Korea Institute of Science & Technology
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Ki-Hwan Bae, Yong-Bok Park, Myung-Sook Choi, Surk-Sik Moon, Yong-Kook Kwon, Eun-Sook Lee, Byung-Hwa Hyun, Yang-Kyu Choi, Chul-Ho Lee, Jun-Sung Lee, Kwang-Hee Son, Byoung-Mog Kwon, Young-Kook Kim, Doil Choi, Sung-Uk Kim, Ingyu Hwang, Jung-Ah Ahn, Young-Bae Park, Hyo-Soo Kim, Seong-Choon Choe
  • Patent number: 6133311
    Abstract: A method for treating or preventing an elevated blood lipid level-related diseases such as hyperlipidemia, arteriosclerosis, angina pectoris, stroke and hepatic diseases in a mammal, which comprises administering thereto an effective amount of tannin, gallic acid or ellagic acid.
    Type: Grant
    Filed: September 15, 1999
    Date of Patent: October 17, 2000
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Ki-Hwan Bae, Yong-Bok Park, Myung-Sook Choi, Surk-Sik Moon, Yong-Kook Kwon, Eun-Sook Lee, Byung-Hwa Hyun, Yang-Kyu Choi, Chul-Ho Lee, Sae-Bom Lee, Young-Bae Park, Hyo-Soo Kim
  • Patent number: 6133241
    Abstract: A method for increasing the plasma high density lipoprotein(HDL) level in a mammal comprises administering a bioflavonoid of formula(I) or plant extract containing same thereto: ##STR1## wherein, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5.sub.7 R.sup.6, R.sup.7, R.sup.8 and R.sup.9 are each independently hydrogen; a hydroxy group; a C.sub.1-9 alkoxy group optionally substituted with one or more substituents selected from the group consisting of a hydroxy, C.sub.1-5 alkoxy, aryloxy, and phenyl group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen, nitro and amido group; a C.sub.5-9 cycloalkyloxy group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen, nitro and amido group; a C.sub.5-9 cycloalkylcarbonyloxy group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen, nitro and amido group; a C.sub.2-10 or C.sub.
    Type: Grant
    Filed: October 22, 1998
    Date of Patent: October 17, 2000
    Assignee: Korea Institute of Science & Technology
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Surk-Sik Moon, Yong-Kook Kwon, Byung-Hwa Hyun, Chul-Ho Lee, Yang-Kyu Choi, Myung-Sook Choi, Sung-Gyu Kim, Og-Sung Moon, Sae-Bom Lee, Eun-Sook Lee, Byung-Tae Ahn
  • Patent number: 6096364
    Abstract: A method for lowering the blood glucose level in a mammal comprises administering an effective amount of a hesperetin or naringenin bioflavonoid.
    Type: Grant
    Filed: October 22, 1998
    Date of Patent: August 1, 2000
    Assignee: Korea Institute of Science & Technology
    Inventors: Song-Hae Bok, Tae-Sook Jeong, Ki-Hwan Bae, Yong-Bok Park, Myung-Sook Choi, Surk-Sik Moon, Yong-Kook Kwon, Eun-Sook Lee, Byung-Hwa Hyun, Yang-Kyu Choi, Chul-Ho Lee, Byung-Tae Ahn, Sae-Bom Lee