Patents by Inventor C. Casey Cunningham

C. Casey Cunningham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS OF USE FOR POST-RADIATION PROTECTION
    Publication number: 20110020432
    Abstract: The present disclosure is directed to methods of administering RL1P76 or an active fragment thereof more than 24 hours after radiation exposure, wherein administration is effective for the protection and treatment of mammals exposed to radiation. In addition, compositions are disclosed including RLIP76 and other radioprotective agents, for example antioxidants.
    Type: Application
    Filed: July 23, 2010
    Publication date: January 27, 2011
    Applicant: TERAPIO CORPORATION
    Inventor: C. Casey Cunningham
  • COMPOSITIONS FOR DELIVERY OF CARGO SUCH AS DRUGS PROTEINS AND/OR GENETIC MATERIALS
    Publication number: 20110020433
    Abstract: Compositions and methods for delivery of cargo molecules to a patient or subject in need thereof include a proteoliposome carrier vehicle that incorporates an RLIP76 protein and contains the cargo molecule. The vehicle effectively delivers the cargo molecule systemically throughout the tissues of the body including into the central nervous system.
    Type: Application
    Filed: February 9, 2009
    Publication date: January 27, 2011
    Inventor: C. Casey Cunningham
  • Polyphoshoinositide binding peptides for intracellular drug delivery
    Patent number: 5846743
    Abstract: Methods and compositions for facilitating the transport of a membrane-impermeable extracellular agent having an intracellular activity across the membrane of a cell are provided. The methods involve covalently coupling an amino terminal blocking group to a transport-mediating peptide to form a carrier molecule. The carrier molecule is covalently coupled to the extracellular agent to form a membrane-permeable prodrug. The transport-mediating peptides are highly basic and bind to polyphosphoinositides.
    Type: Grant
    Filed: November 22, 1996
    Date of Patent: December 8, 1998
    Assignee: Brigham and Women's Hospital, Inc.
    Inventors: Paul A. Janmey, C. Casey Cunningham, John H. Hartwig, Thomas P. Stossel, Roland Vegner
  • Polyphosphoinsitide binding peptides for intracellular drug delivery
    Patent number: 5783662
    Abstract: Methods and compositions for facilitating the transport of a membrane-impermeable extracellular agent having an intracellular activity across the membrane of a cell are provided. The methods involve covalently coupling an amino terminal blocking group to a transport-mediating peptide to form a carrier molecule. The carrier molecule is covalently coupled to the extracellular agent to form a membrane-permeable prodrug. The transport-mediating peptides are highly basic and bind to polyphosphoinositides.
    Type: Grant
    Filed: April 11, 1997
    Date of Patent: July 21, 1998
    Assignee: Brigham & Women's Hospital, Inc.
    Inventors: Paul A. Janmey, C. Casey Cunningham, John H. Hartwig, Thomas P. Stossel, Roland Vegner