Abstract: Medical waste, i.e., infectious material such as needles and sharps, are contained in a system that meets Federal Regulations concerning the storage and disposal of medical waste, while also meeting Federal Regulations concerning transportation of such medical waste, yet also is environmental friendly upon disposal. The system includes a one-piece, monolithic plastic bottle contained in a unitary metal outer container, with a one-way plug located in a neck of the bottle to permit items to enter the bottle but to prevent those items from leaving the bottle via the neck. A closure is attached to the neck, with a lid and an overcap ring covering the closed bottle for shipping. Adhesive material can be used to further seal the system, with the container being placed in a corrugated carton that is then sealed with further adhesive for transportation.