Abstract: The methods of the present invention are useful for determining whether an individual has or is at risk of developing a neuroimmune-based psychiatric disorder by detecting the expression level of one or more cytokine receptors in a biological sample. The methods of the present invention are also useful for the in vivo imaging of brain tissue by detecting one or more imaging agents such as ligands (e.g., cytokines) that bind to one or more cytokine receptors. In addition, the methods of the present invention are useful for identifying compounds that modulate (e.g., increase) the expression level or activity of one or more cytokine receptors. The present invention further provides therapeutic methods that target one or more cytokine receptors for the treatment of a neuroimmune-based psychiatric disorder.

Abstract: Disclosed is a mattress cover. The mattress cover includes a top panel and a bottom panel, and a covering member. The top panel and the bottom panel are coupled to configure an enclosure having a side opening. Further, the covering member extends from at least one of the top panel and the bottom panel. The covering member is capable of being folded inwardly to releasably close the side opening of the enclosure.