Patents by Inventor Camilo Ayala Breton

Camilo Ayala Breton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REPLICATION-COMPETENT VESICULAR STOMATITIS VIRUSES
    Publication number: 20240000873
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.
    Type: Application
    Filed: June 20, 2023
    Publication date: January 4, 2024
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Kah-Whye Peng, Stephen James Russell, Camilo Ayala Breton
  • DNA COMPOSITIONS AND RELATED METHODS
    Publication number: 20230255999
    Abstract: The disclosure provides, for example, single stranded, covalently closed DNA that does not form a double stranded structure longer than 100 base pairs. The ssDNA may encode an effector sequence, for instance a therapeutic protein. The ssDNA may comprise a nuclear targeting sequence (NTS). In some embodiments, the ssDNA shows decreased activation of the innate immune system compared to an otherwise similar dsDNA.
    Type: Application
    Filed: November 11, 2022
    Publication date: August 17, 2023
    Inventors: Alexandra Rachael Sneider, Jacob Rosenblum Rubens, Narahari Subbanna Pujar, Molly Krisann Gibson, Benjamin Andrew Portney, Geoffrey A. Von Maltzahn, Camilo Ayala Breton
  • Replication-competent vesicular stomatitis viruses
    Patent number: 11723937
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.
    Type: Grant
    Filed: March 3, 2020
    Date of Patent: August 15, 2023
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Kah-Whye Peng, Stephen James Russell, Camilo Ayala Breton
  • TARGETING PD-L1 ON TUMOR CELLS
    Publication number: 20220396625
    Abstract: This document relates to materials and methods for treating cancer. For example, this document provides materials and methods for using PD-L1 targeting domains in bispecific chimeric polypeptides, chimeric transmembrane polypeptides, genetically modified viruses, nucleic acid vectors, and/or fusion-inducing cells to treat cancer.
    Type: Application
    Filed: July 7, 2022
    Publication date: December 15, 2022
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Autumn J. Schulze, Arun Ammayappan, Kah-Whye Peng, Camilo Ayala Breton
  • Targeting PD-L1 on tumor cells
    Patent number: 11414491
    Abstract: This document relates to materials and methods for treating cancer. For example, this document provides materials and methods for using PD-L1 targeting domains in bispecific chimeric polypeptides, chimeric transmembrane polypeptides, genetically modified viruses, nucleic acid vectors, and/or fusion-inducing cells to treat cancer.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: August 16, 2022
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James Russell, Autumn J. Schulze, Arun Ammayappan, Kah-Whye Peng, Camilo Ayala Breton
  • REPLICATION-COMPETENT VESICULAR STOMATITIS VIRUSES
    Publication number: 20200206286
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.
    Type: Application
    Filed: March 3, 2020
    Publication date: July 2, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Kah-Whye Peng, Stephen James Russell, Camilo Ayala Breton
  • Replication-competent vesicular stomatitis viruses
    Patent number: 10610553
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: April 7, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Kah-Whye Peng, Stephen James Russell, Camilo Ayala Breton
  • TARGETING PD-L1 ON TUMOR CELLS
    Publication number: 20190169296
    Abstract: This document relates to materials and methods for treating cancer. For example, this document provides materials and methods for using PD-L1 targeting domains in bispecific chimeric polypeptides, chimeric transmembrane polypeptides, genetically modified viruses, nucleic acid vectors, and/or fusion-inducing cells to treat cancer.
    Type: Application
    Filed: May 18, 2017
    Publication date: June 6, 2019
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Stephen James RUSSELL, Autumn J. RUIZ, Arun AMMAYAPPAN, Kah-Whye PENG, Camilo Ayala BRETON
  • REPLICATION-COMPETENT VESICULAR STOMATITIS VIRUSES
    Publication number: 20180214497
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.
    Type: Application
    Filed: January 8, 2018
    Publication date: August 2, 2018
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Kah-Whye Peng, Stephen James Russell, Camilo Ayala Breton
  • Replication-competent vesicular stomatitis viruses
    Patent number: 9861668
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: January 9, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Kah-Whye Peng, Stephen James Russell, Camilo Ayala Breton
  • REPLICATION-COMPETENT VESICULAR STOMATITIS VIRUSES
    Publication number: 20170157187
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.
    Type: Application
    Filed: December 15, 2016
    Publication date: June 8, 2017
    Inventors: Kah-Whye Peng, Stephen James Russell, Camilo Ayala Breton
  • Replication-competent vesicular stomatitis viruses
    Patent number: 9555067
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: January 31, 2017
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Kah-Whye Peng, Stephen James Russell, Camilo Ayala Breton
  • REPLICATION-COMPETENT VESICULAR STOMATITIS VIRUSES
    Publication number: 20150079037
    Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, replication-competent vesicular stomatitis viruses, nucleic acid molecules encoding replication-competent vesicular stomatitis viruses, methods for making replication-competent vesicular stomatitis viruses, and methods for using replication-competent vesicular stomatitis viruses to treat cancer or infectious diseases are provided.
    Type: Application
    Filed: March 13, 2013
    Publication date: March 19, 2015
    Inventors: Kah-Whye Peng, Stephen James Russell, Camilo Ayala Breton