Patents by Inventor CANDACE BICHSEL

CANDACE BICHSEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bacterial mediated delivery of nuclear protein into pluripotent and differentiated cells
    Patent number: 8617888
    Abstract: A modified P. aeruginosa type III secretion system has been developed that efficiently delivers selected proteins into a host cell. In one example, a functional nuclear Cre Recombinase is injected into embryonic stem (ES) cells and can be used to induce pluripotent stem (iPS) cells. This method of in vitro lineage directed differentiation prevents insertional mutagenesis and provides a route to selected stem cell renewal and cell-based therapies.
    Type: Grant
    Filed: July 23, 2010
    Date of Patent: December 31, 2013
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Shouguang Jin, Candace Bichsel
  • Bacterial Mediated Delivery of Nuclear Protein Into Pluripotent and Differentiated Cells
    Publication number: 20120021517
    Abstract: A modified P. aeruginosa type III secretion system has been developed that efficiently delivers selected proteins into a host cell. In one example, a functional nuclear Cre Recombinase is injected into embryonic stem (ES) cells and can be used to induce pluripotent stem (iPS) cells. This method of in vitro lineage directed differentiation prevents insertional mutagenesis and provides a route to selected stem cell renewal and cell-based therapies.
    Type: Application
    Filed: July 23, 2010
    Publication date: January 26, 2012
    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: SHOUGUANG JIN, CANDACE BICHSEL