Patents by Inventor Candace Y. W. Lee
Candace Y. W. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10344068Abstract: This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal conditions. For example, chimeric polypeptides having at least one amino acid segment (e.g., N-terminus tail, ring structure, C-terminus tail, or a combination thereof) of a natriuretic peptide (e.g., ANP, BNP, CNP, URO, or DNP) and an amino acid segment of an angiotensin polypeptide (e.g., Ang-(1-7)) are provided.Type: GrantFiled: January 20, 2017Date of Patent: July 9, 2019Assignee: Mayo Foundation for Medical Education and ResearchInventors: Candace Y. W. Lee, John C. Burnett, Jr.
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Patent number: 9771405Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.Type: GrantFiled: May 13, 2016Date of Patent: September 26, 2017Assignee: Mayo Foundation for Medical Education and ResearchInventors: John C. Burnett, Jr., Candace Y. W. Lee
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Publication number: 20170129934Abstract: This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal conditions. For example, chimeric polypeptides having at least one amino acid segment (e.g., N-terminus tail, ring structure, C-terminus tail, or a combination thereof) of a natriuretic peptide (e.g., ANP, BNP, CNP, URO, or DNP) and an amino acid segment of an angiotensin polypeptide (e.g., Ang-(1-7)) are provided.Type: ApplicationFiled: January 20, 2017Publication date: May 11, 2017Inventors: Candace Y.W. Lee, John C. Burnett, JR.
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Patent number: 9587004Abstract: This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal conditions. For example, chimeric polypeptides having at least one amino acid segment (e.g., N-terminus tail, ring structure, C-terminus tail, or a combination thereof) of a natriuretic peptide (e.g., ANP, BNP, CNP, URO, or DNP) and an amino acid segment of an angiotensin polypeptide (e.g., Ang-(1-7)) are provided.Type: GrantFiled: August 9, 2016Date of Patent: March 7, 2017Assignee: Mayo Foundation for Medical Education and ResearchInventors: Candace Y. W. Lee, John C. Burnett, Jr.
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Publication number: 20160362468Abstract: This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal conditions. For example, chimeric polypeptides having at least one amino acid segment (e.g., N-terminus tail, ring structure, C-terminus tail, or a combination thereof) of a natriuretic peptide (e.g., ANP, BNP, CNP, URO, or DNP) and an amino acid segment of an angiotensin polypeptide (e.g., Ang-(1-7)) are provided.Type: ApplicationFiled: August 9, 2016Publication date: December 15, 2016Inventors: Candace Y.W. Lee, John C. Burnett, Jr.
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Patent number: 9441027Abstract: This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal conditions. For example, chimeric polypeptides having at least one amino acid segment (e.g., N-terminus tail, ring structure, C-terminus tail, or a combination thereof) of a natriuretic peptide (e.g., ANP, BNP, CNP, URO, or DNP) and an amino acid segment of an angiotensin polypeptide (e.g., Ang-(1-7)) are provided.Type: GrantFiled: July 2, 2015Date of Patent: September 13, 2016Assignee: Mayo Foundation for Medical Education and ResearchInventors: Candace Y.W. Lee, John C. Burnett, Jr.
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Publication number: 20160244500Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.Type: ApplicationFiled: May 13, 2016Publication date: August 25, 2016Inventors: John C. Burnett, JR., Candace Y.W. Lee
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Patent number: 9365631Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.Type: GrantFiled: July 28, 2015Date of Patent: June 14, 2016Assignee: Mayo Foundation for Medical Education and ResearchInventors: John C. Burnett, Jr., Candace Y. W. Lee
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Publication number: 20150322127Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.Type: ApplicationFiled: July 28, 2015Publication date: November 12, 2015Inventors: John C. Burnett, Jr., Candace Y.W. Lee
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Publication number: 20150299284Abstract: This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal conditions. For example, chimeric polypeptides having at least one amino acid segment (e.g., N-terminus tail, ring structure, C-terminus tail, or a combination thereof) of a natriuretic peptide (e.g., ANP, BNP, CNP, URO, or DNP) and an amino acid segment of an angiotensin polypeptide (e.g., Ang-(1-7)) are provided.Type: ApplicationFiled: July 2, 2015Publication date: October 22, 2015Inventors: Candace Y.W. Lee, John C. Burnett, JR.
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Patent number: 9115209Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.Type: GrantFiled: April 21, 2014Date of Patent: August 25, 2015Assignee: Mayo Foundation for Medical Education and ResearchInventors: John C. Burnett, Jr., Candace Y. W. Lee
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Patent number: 9102707Abstract: This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal conditions. For example, chimeric polypeptides having at least one amino acid segment (e.g., N-terminus tail, ring structure, C-terminus tail, or a combination thereof) of a natriuretic peptide (e.g., ANP, BNP, CNP, URO, or DNP) and an amino acid segment of an angiotensin polypeptide (e.g., Ang-(1-7)) are provided.Type: GrantFiled: August 21, 2012Date of Patent: August 11, 2015Assignee: Mayo Foundation for Medical Education and ResearchInventors: Candace Y. W. Lee, John C. Burnett, Jr.
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Publication number: 20140228294Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.Type: ApplicationFiled: April 21, 2014Publication date: August 14, 2014Applicant: Mayo Foundation for Medical Education and ResearchInventors: John C. Burnett, JR., Candace Y.W. Lee
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Patent number: 8741842Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.Type: GrantFiled: June 16, 2009Date of Patent: June 3, 2014Assignee: Mayo Foundation for Medical Education and ResearchInventors: John C. Burnett, Jr., Candace Y. W. Lee
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Publication number: 20140005358Abstract: This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal conditions. For example, chimeric polypeptides having at least one amino acid segment (e.g., N-terminus tail, ring structure, C-terminus tail, or a combination thereof) of a natriuretic peptide (e.g., ANP, BNP, CNP, URO, or DNP) and an amino acid segment of an angiotensin polypeptide (e.g., Ang-(1-7)) are provided.Type: ApplicationFiled: August 21, 2012Publication date: January 2, 2014Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCHInventors: Candace Y.W. Lee, John C. Burnett, Jr.
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Publication number: 20110152191Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.Type: ApplicationFiled: June 16, 2009Publication date: June 23, 2011Applicant: National Institutes of Health (NIH)Inventors: John C. Burnett, Jr., Candace Y.W. Lee
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Patent number: 7754852Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing natriuretic activities within a mammal.Type: GrantFiled: July 18, 2008Date of Patent: July 13, 2010Assignee: Mayo Foundation for Medical Education and ResearchInventors: John C. Burnett, Jr., Candace Y. W. Lee
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Publication number: 20090054337Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing natriuretic activities within a mammal.Type: ApplicationFiled: July 18, 2008Publication date: February 26, 2009Inventors: John C. Burnett, JR., Candace Y.W. Lee