Patents by Inventor Carl Hulle

Carl Hulle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conjugation of multiple vancomycin molecules on a polyvinyl alcohol backbone for the capture of microorganisms
    Patent number: 9910037
    Abstract: The present disclosure relates to compositions, methods, and kits for the rapid detection, separation and/or isolation of microorganisms. Specifically, the disclosure relates to compositions, methods, and kits for using vancomycin—PVA backbone complexes to capture and/or concentrate microorganisms in an aqueous sample, such as gram positive and/or gram negative bacteria in solution.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: March 6, 2018
    Assignee: Iris International, Inc.
    Inventors: Edward Jablonski, Carl Hulle
  • Method of capturing bacteria on polylysine-coated microspheres
    Patent number: 9766237
    Abstract: The present disclosure relates to compositions, methods, and kits for the detection, separation and/or isolation of microorganisms. Specifically, the disclosure relates to compositions, methods, and kits for using polylysine-coated particles to capture microorganisms such as bacteria.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 19, 2017
    Assignee: Iris International, Inc.
    Inventors: Edward Jablonski, Carl Hulle
  • CONJUGATION OF MULTIPLE VANCOMYCIN MOLECULES ON A POLYVINYL ALCOHOL BACKBONE FOR THE CAPTURE OF MICROORGANISMS
    Publication number: 20160041166
    Abstract: The present disclosure relates to compositions, methods, and kits for the rapid detection, eparation and/or isolation of microorganisms. Specifically, the disclosure relates to compositions, methods, and kits for using vancomycin—PVA backbone complexes to capture and/or concentrate microorganisms in an aqueous sample, such as gram positive and/or gram negative bacteria in solution.
    Type: Application
    Filed: March 13, 2014
    Publication date: February 11, 2016
    Inventors: Edward Jablonski, Carl Hulle
  • METHOD OF CAPTURING BACTERIA ON POLYLYSINE-COATED MICROSPHERES
    Publication number: 20160033503
    Abstract: The present disclosure relates to compositions, methods, and kits for the detection, separation and/or isolation of microorganisms. Specifically, the disclosure relates to compositions, methods, and kits for using polylysine-coated particles to capture microorganisms such as bacteria.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: Edward Jablonski, Carl Hulle
  • Method for making encapsulated gas microspheres from heat denatured protein in the absence of oxygen gas
    Patent number: 5855865
    Abstract: Elastic protein microspheres, filled with water insoluble gases, have been produced by ultrasound and mechanical cavitation without the present of oxygen. The microspheres are highly echogenic. The microspheres exhibit greatly enhanced static pressure stability, up to 40 psig. The microspheres are resistant to coalescence and to expansion due to differential gas diffusion. The microspheres are resistant to collapse when suspended in a gas-depleted aqueous solution.
    Type: Grant
    Filed: July 2, 1997
    Date of Patent: January 5, 1999
    Assignee: Molecular Biosystems, Inc.
    Inventors: Karel J. Lambert, Sheila Benay Podell, Edward G. Jablonski, Carl Hulle, Kenneth Hamilton, Rolf Lohrmann
  • Method of making encapsulated gas microspheres useful as an ultrasonic imaging agent
    Patent number: 5552133
    Abstract: Encapsulated gas microspheres useful as an ultrasonic imaging agent are made by: mixing an aqueous solution of a heat-denaturable protein with a gas, and passing the gas-solution mixture through a mill whereby the mixture is emulsified near the denaturation temperature of the protein and subjected to mechanical shearing and cavitation which causes the formation of gas bubbles in the 0.1 to 10 micron range, and the protein to locally denature and deposit at the gas-liquid interface to form the encapsulated microspheres.
    Type: Grant
    Filed: August 12, 1994
    Date of Patent: September 3, 1996
    Assignee: Molecular Biosystems, Inc.
    Inventors: Karel J. Lambert, Edward G. Jablonski, Carl Hulle