Patents by Inventor Carl M. Blumenfeld

Carl M. Blumenfeld has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR SYNTHESIS OF THERAPEUTIC NANOPARTICLES
    Publication number: 20230355800
    Abstract: Improved methods and reactants for the chemical synthesis of therapeutic nanoparticles are provided. The nanoparticles comprise a polymeric core, to which is attached one or more homing molecules and one or more therapeutic agents. Improvements in speed, yield and purity are attained using the methods disclosed herein.
    Type: Application
    Filed: June 28, 2023
    Publication date: November 9, 2023
    Inventors: Emily A. Wyent, Carl M. Blumenfeld, Robert J. Lamm
  • Methods and compositions for synthesis of therapeutic nanoparticles
    Patent number: 11738092
    Abstract: Improved methods and reactants for the chemical synthesis of therapeutic nanoparticles are provided. The nanoparticles comprise a polymeric core, to which is attached one or more homing molecules and one or more therapeutic agents. Improvements in speed, yield and purity are attained using the methods disclosed herein.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: August 29, 2023
    Assignee: Dantari, Inc.
    Inventors: Emily A. Wyent, Carl M. Blumenfeld, Robert J. Lamm
  • PHOTOCATALYTIC GENERATION OF SINGLET OXYGEN FOR AIR PURIFICATION
    Publication number: 20220211894
    Abstract: Aspects disclosed herein include a system for generating singlet oxygen in a gas, the system comprising: a substrate; and hexanuclear clusters operably immobilized on at least a portion of the substrate; wherein each hexanuclear cluster comprises a photosensitive octahedral core complex characterized by formula FX1a: M6X8 (FX1a); wherein each M is independently Mo, W, or Re; wherein each X is independently a halide anion ligand; wherein the clusters are exposed to the gas and the gas comprises O2 gas; wherein the clusters are exposed to a light; and wherein each hexanuclear cluster is a photosensitizer configured to generate the gaseous singlet oxygen when irradiated by the light in the presence of the O2 gas.
    Type: Application
    Filed: November 11, 2021
    Publication date: July 7, 2022
    Applicant: California Institute of Technology
    Inventors: Robert H. GRUBBS, Carl M. BLUMENFELD, Harry B. GRAY, George R. ROSSMAN
  • METHODS AND COMPOSITIONS FOR SYNTHESIS OF THERAPEUTIC NANOPARTICLES
    Publication number: 20210170049
    Abstract: Improved methods and reactants for the chemical synthesis of therapeutic nanoparticles are provided. The nanoparticles comprise a polymeric core, to which is attached one or more homing molecules and one or more therapeutic agents. Improvements in speed, yield and purity are attained using the methods disclosed herein.
    Type: Application
    Filed: December 4, 2020
    Publication date: June 10, 2021
    Inventors: Emily A. Wyatt, Carl M. Blumenfeld, Robert J. Lamm
  • DNA-functionalized scaffolds for drug capture applications
    Patent number: 10646505
    Abstract: This disclosure is directed to structured compositions, including DNA-functionalized scaffolds, for drug capture, and methods and devices for sequestering chemotherapeutics from physiological fluids using the functionalized scaffolds.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: May 12, 2020
    Assignee: California Institute of Technology
    Inventors: Michael D. Schulz, Carl M. Blumenfeld, Robert H. Grubbs, Julia R. Greer, Daryl Wei Liang Yee
  • DNA-FUNCTIONALIZED SCAFFOLDS FOR DRUG CAPTURE APPLICATIONS
    Publication number: 20180064747
    Abstract: This disclosure is directed to structured compositions, including DNA-functionalized scaffolds, for drug capture, and methods and devices for sequestering chemotherapeutics from physiological fluids using the functionalized scaffolds.
    Type: Application
    Filed: September 6, 2017
    Publication date: March 8, 2018
    Inventors: MICHAEL D. SCHULZ, CARL M. BLUMENFELD, ROBERT H. GRUBBS, JULIA R. GREER, DARYL WEI LIANG YEE
  • Sulfonic esters of metal oxides and methods of their use
    Patent number: 9636428
    Abstract: The present disclosure is directed to sulfonic esters of metal oxides including those of formulas I and II:
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: May 2, 2017
    Assignees: California Institute of Technology, Children's Hospital of Los Angeles
    Inventors: Carl M. Blumenfeld, Karn Sorasaenee, Harry B. Gray, Robert H. Grubbs
  • Sulfonic esters of metal oxides and methods of their use
    Patent number: 9580451
    Abstract: The present invention is directed to sulfonic esters of metal oxides including those of formulas I and II:
    Type: Grant
    Filed: January 26, 2015
    Date of Patent: February 28, 2017
    Assignees: California Institute of Technology, Children's Hospital of Los Angeles
    Inventors: Carl M. Blumenfeld, Harry B. Gray, Robert H. Grubbs, Karn Sorasaenee
  • Sulfonic Esters of Metal Oxides and Methods of Their Use
    Publication number: 20150202331
    Abstract: The present disclosure is directed to sulfonic esters of metal oxides including those of formulas I and II:
    Type: Application
    Filed: September 22, 2014
    Publication date: July 23, 2015
    Inventors: Carl M. Blumenfeld, Karn Sorasaenee, Harry B. Gray, Robert H. Grubbs
  • Sulfonic Esters Of Metal Oxides And Methods Of Their Use
    Publication number: 20150141640
    Abstract: The present invention is directed to sulfonic esters of metal oxides including those of formulas I and II:
    Type: Application
    Filed: January 26, 2015
    Publication date: May 21, 2015
    Inventors: Carl M. Blumenfeld, Harry B. Gray, Robert H. Grubbs, Karn Sorasaenee
  • Sulfonic esters of metal oxides and methods of their use
    Patent number: 8968789
    Abstract: The present invention is directed to sulfonic esters of metal oxides including those of formulas I and II:
    Type: Grant
    Filed: February 12, 2014
    Date of Patent: March 3, 2015
    Assignees: California Institute of Technology, Children's Hospital of Los Angeles
    Inventors: Carl M. Blumenfeld, Harry B. Gray, Robert H. Grubbs, Karn Sorasaenee
  • Sulfonic Esters Of Metal Oxides And Methods Of Their Use
    Publication number: 20140227187
    Abstract: The present invention is directed to sulfonic esters of metal oxides including those of formulas I and II:
    Type: Application
    Filed: February 12, 2014
    Publication date: August 14, 2014
    Applicants: Children's Hospital Of Los Angeles, California Institute of Technology
    Inventors: Carl M. Blumenfeld, Harry B. Gray, Robert H. Grubbs, Karn Sorasaenee